PDB: 45118 resultsInfo pagesStatus searchChemie searchBIRD

---

378D	STRUCTURE OF THE SIDE-BY-SIDE BINDING OF DISTAMYCIN TO DNA Descriptor: DISTAMYCIN A, DNA (5'-D(*GP*TP*AP*TP*AP*TP*AP*C)-3'), SODIUM ION Authors: Mitra, S.N, Wahl, M.C, Sundaralingam, M. Deposit date: 1998-01-28 Release date: 1999-03-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of the side-by-side binding of distamycin to d(GTATATAC)2. Acta Crystallogr.,Sect.D, 55, 1999
6IFF	Crystal structure of M1 zinc metallopeptidase E323A mutant from Deinococcus radiodurans Descriptor: SODIUM ION, TYROSINE, ZINC ION, ... Authors: Agrawal, R, Kumar, A, Kumar, A, Gaur, N.K, Makde, R.D. Deposit date: 2018-09-20 Release date: 2019-09-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase. Int.J.Biol.Macromol., 147, 2020
6ILR	Structure of Arabidopsis thaliana Ribokinase in unligand form Descriptor: Ribokinase, SODIUM ION, TETRAETHYLENE GLYCOL Authors: Kang, P, Oh, J, Rhee, S. Deposit date: 2018-10-19 Release date: 2019-03-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.972 Å) Cite: Crystal structure and mutational analyses of ribokinase from Arabidopsis thaliana. J. Struct. Biol., 206, 2019
6IPF	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mn-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
3A07	Crystal Structure of Actinohivin; Potent anti-HIV Protein Descriptor: Actinohivin, SODIUM ION Authors: Tsunoda, M, Suzuki, K, Sagara, T, Takenaka, A. Deposit date: 2009-03-04 Release date: 2009-08-25 Last modified: 2017-10-11 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Mechanism by which the lectin actinohivin blocks HIV infection of target cells Proc.Natl.Acad.Sci.USA, 106, 2009
6IPD	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
4BDR	Crystal structure of the GluK2 R775A LBD dimer in complex with kainate Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... Authors: Nayeem, N, Mayans, O, Green, T. Deposit date: 2012-10-05 Release date: 2013-04-10 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Correlating Efficacy and Desensitization with Gluk2 Ligand-Binding Domain Movements. Open Biol., 3, 2013
4AW1	Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the PIF-Pocket Descriptor: 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... Authors: Schulze, J.O, Busschots, K, Lopez-Garcia, L.A, Lammi, C, Stroba, A, Zeuzem, S, Piiper, A, Alzari, P.M, Neimanis, S, Arencibia, J.M, Engel, M, Biondi, R.M. Deposit date: 2012-05-30 Release date: 2012-10-03 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Substrate-Selective Inhibition of Protein Kinase Pdk1 by Small Compounds that Bind to the Pif-Pocket Allosteric Docking Site. Chem.Biol., 19, 2012
4DOB	Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate: Stereoselective binding of R-isomer Descriptor: 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... Authors: Batra, V.K. Deposit date: 2012-02-09 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Beta,Gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases J.Am.Chem.Soc., 134, 2012
6H7L	ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST DOBUTAMINE AND NANOBODY Nb6B9 Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, DOBUTAMINE, ... Authors: Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. Deposit date: 2018-07-31 Release date: 2018-10-17 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular basis for high-affinity agonist binding in GPCRs. Science, 364, 2019
6H7O	ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND WEAK PARTIAL AGONIST CYANOPINDOLOL AND NANOBODY Nb6B9 Descriptor: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, ... Authors: Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. Deposit date: 2018-07-31 Release date: 2018-10-17 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Molecular basis for high-affinity agonist binding in GPCRs. Science, 364, 2019
6GW1	GII.10 human norovirus protruding domain in complex with glycochenodeoxycholate (GCDCA) Descriptor: Capsid protein, GLYCOCHENODEOXYCHOLIC ACID, SODIUM ION Authors: Kilic, T, Hansman, G.S. Deposit date: 2018-06-21 Release date: 2018-10-17 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for Human Norovirus Capsid Binding to Bile Acids. J. Virol., 93, 2019
4DOA	Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: non-interactive binding of s-isomer Descriptor: 2'-deoxy-5'-O-[(R)-{[(R)-[(S)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]guanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... Authors: Batra, V.K. Deposit date: 2012-02-09 Release date: 2012-06-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.051 Å) Cite: Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases J.Am.Chem.Soc., 134, 2012
6J6V	Crystal structure of heat shock factor 4-DBD Descriptor: Heat shock factor protein 4, NITRATE ION, SODIUM ION Authors: Guo, L, Xiao, Z.Y, Wang, S, Liu, W. Deposit date: 2019-01-16 Release date: 2020-01-22 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Structure of heat shock factor 4-DBD at 1.20 Angstroms resolution. To Be Published
6IX5	The structure of LepI complex with SAM and its substrate analogue Descriptor: 1,2-ETHANEDIOL, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, CHLORIDE ION, ... Authors: Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. Deposit date: 2018-12-09 Release date: 2019-07-17 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat.Chem., 11, 2019
1O00	Human mitochondrial aldehyde dehydrogenase complexed with NAD+ and Mg2+ showing dual NAD(H) conformations Descriptor: Aldehyde dehydrogenase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Perez-Miller, S.J, Hurley, T.D. Deposit date: 2003-02-20 Release date: 2003-06-24 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase Biochemistry, 42, 2003
1OCO	BOVINE HEART CYTOCHROME C OXIDASE IN CARBON MONOXIDE-BOUND STATE Descriptor: CARBON MONOXIDE, COPPER (II) ION, CYTOCHROME C OXIDASE, ... Authors: Tsukihara, T, Yao, M. Deposit date: 1998-07-09 Release date: 1999-07-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science, 280, 1998
4B6C	Structure of the M. smegmatis GyrB ATPase domain in complex with an aminopyrazinamide Descriptor: 6-(3,4-dimethylphenyl)-3-[[4-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]amino]pyrazine-2-carboxamide, DNA gyrase subunit B,DNA gyrase subunit B,DNA gyrase subunit B, SODIUM ION Authors: Tucker, J.A, Shirude, P.S, Madhavapeddi, P, Hussein, S, Basu, R, Ghorpade, S. Deposit date: 2012-08-09 Release date: 2013-01-23 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis. ACS Chem. Biol., 8, 2013
6HBX	The structure of the G. violaceus guanidine II riboswitch P2 stem-loop with ethylguanidine Descriptor: N-ETHYLGUANIDINE, RNA (5'-R(*GP*GP*UP*GP*GP*GP*GP*AP*CP*GP*AP*CP*CP*CP*CP*AP*(CBV)P*C)-3'), SODIUM ION, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2018-08-13 Release date: 2019-02-20 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Structure-guided design of a high-affinity ligand for a riboswitch. Rna, 25, 2019
4D0P	Crystal structure of human CSN4 Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, COP9 SIGNALOSOME COMPLEX SUBUNIT 4, ... Authors: Bunker, R.D, Lingaraju, G.M, Thoma, N.H. Deposit date: 2014-04-29 Release date: 2014-07-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal Structure of the Cop9 Signalosome Nature, 512, 2014
6HDZ	Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine Descriptor: 1,2-ETHANEDIOL, 5'-O-(N-(L-seryl)-Sulfamoyl)uridine, SODIUM ION, ... Authors: Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. Deposit date: 2018-08-20 Release date: 2019-12-04 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
1OCZ	BOVINE HEART CYTOCHROME C OXIDASE IN AZIDE-BOUND STATE Descriptor: AZIDE ION, COPPER (II) ION, CYTOCHROME C OXIDASE, ... Authors: Tsukihara, T, Yao, M. Deposit date: 1998-07-13 Release date: 1999-07-22 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science, 280, 1998
3SJL	Crystal Structure of the P107S-MauG/pre-Methylamine Dehydrogenase Complex Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... Authors: Jensen, L.M.R, Wilmot, C.M. Deposit date: 2011-06-21 Release date: 2012-05-02 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Proline 107 is a major determinant in maintaining the structure of the distal pocket and reactivity of the high-spin heme of MauG. Biochemistry, 51, 2012
1OCR	BOVINE HEART CYTOCHROME C OXIDASE IN THE FULLY REDUCED STATE Descriptor: COPPER (II) ION, CYTOCHROME C OXIDASE, HEME-A, ... Authors: Tsukihara, T, Yao, M. Deposit date: 1998-07-07 Release date: 1999-07-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science, 280, 1998
6J3B	Crystal structure of human DHODH in complex with inhibitor 1289 Descriptor: (6R)-1-[3,5-bis(fluoranyl)-4-[2-fluoranyl-5-(hydroxymethyl)phenyl]phenyl]-6-propan-2-yl-6,7-dihydro-5H-benzotriazol-4-one, ACETATE ION, CHLORIDE ION, ... Authors: Yu, Y, Chen, Q. Deposit date: 2019-01-04 Release date: 2019-08-21 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode. Febs Open Bio, 9, 2019

<173174175176177178179180181182183184185186187188>