8SCH
 
 | | TCEI_III NMR Structure | | Descriptor: | RNA (68-MER) | | Authors: | Warden, M.S, Mueller, G.A, Hall, T.M.T. | | Deposit date: | 2023-04-05 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos.
Nucleic Acids Res., 51, 2023
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8SCF
 | | TCEIII NMR Structure | | Descriptor: | RNA (30-MER) | | Authors: | Warden, M.S, Mueller, G.A, Hall, T.M.T. | | Deposit date: | 2023-04-05 | | Release date: | 2023-07-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos.
Nucleic Acids Res., 51, 2023
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8SW7
 | | BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ... | | Authors: | Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. | | Deposit date: | 2023-05-17 | | Release date: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Focusing antibody responses to the fusion peptide in rhesus macaques.
Biorxiv, 2023
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5VVL
 | | Cas1-Cas2 bound to full-site mimic with Ni | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (11-MER), ... | | Authors: | Wright, A.V, Knott, G.J, Doxzen, K.D, Doudna, J.A. | | Deposit date: | 2017-05-19 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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5W0Q
 | | CREBBP Bromodomain in complex with Cpd17 (N,2,7-trimethyl-2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxamide) | | Descriptor: | (2R)-N,2,7-trimethyl-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide, CREB-binding protein, SULFATE ION | | Authors: | Murray, J.M. | | Deposit date: | 2017-05-31 | | Release date: | 2018-03-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
J. Med. Chem., 60, 2017
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1HTY
 | | GOLGI ALPHA-MANNOSIDASE II | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R. | | Deposit date: | 2001-01-02 | | Release date: | 2002-01-02 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
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1HXK
 | | GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R. | | Deposit date: | 2001-01-16 | | Release date: | 2002-01-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
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5W0F
 | | CREBBP Bromodomain in complex with Cpd3 ((S)-1-(3-(6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one) | | Descriptor: | 1-{3-[6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-1-[(3S)-oxolan-3-yl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one, CREB-binding protein | | Authors: | Murray, J.M. | | Deposit date: | 2017-05-30 | | Release date: | 2018-03-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
J. Med. Chem., 60, 2017
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5W0L
 | | CREBBP Bromodomain in complex with Cpd10 (1-(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one) | | Descriptor: | 1-{3-[7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-1-(oxan-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one, CREB-binding protein | | Authors: | Murray, J.M. | | Deposit date: | 2017-05-31 | | Release date: | 2018-03-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.549 Å) | | Cite: | GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
J. Med. Chem., 60, 2017
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3IE4
 | | b-glucan binding domain of Drosophila GNBP3 defines a novel family of pattern recognition receptor | | Descriptor: | 1,2-ETHANEDIOL, Gram-Negative Binding Protein 3, ZINC ION | | Authors: | Mishima, Y, Coste, F, Kellenberger, C, Roussel, A. | | Deposit date: | 2009-07-22 | | Release date: | 2009-08-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The N-terminal domain of drosophila gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors
To be Published
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5CHL
 | | Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin remodeling complex | | Descriptor: | Histone H2A.Z, Vacuolar protein sorting-associated protein 72 homolog | | Authors: | Shan, S, Liang, X, Pan, L, Wu, C, Zhou, Z. | | Deposit date: | 2015-07-10 | | Release date: | 2016-03-09 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (1.892 Å) | | Cite: | Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
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6NQZ
 | | Flagellar protein FcpB from Leptospira interrogans | | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Flagellar coiling protein B, GLYCEROL, ... | | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | Deposit date: | 2019-01-22 | | Release date: | 2020-01-29 | | Last modified: | 2020-03-18 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | An asymmetric sheath controls flagellar supercoiling and motility in the Leptospira spirochete.
Elife, 9, 2020
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3PXN
 | | Crystal structure of the Drosophila kinesin family member Kin10/NOD in complex with divalent manganese and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein Nod, MANGANESE (II) ION | | Authors: | Cochran, J.C, Zhao, Y.C, Wilcox, D.E, Kull, F.J. | | Deposit date: | 2010-12-10 | | Release date: | 2011-12-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A metal switch for controlling the activity of molecular motor proteins.
Nat.Struct.Mol.Biol., 19, 2012
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5VWS
 | | Ligand free structure of Cytochrome P450 TbtJ1 | | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Gober, J.G, Ghodge, S.V, Brustad, E.M, Bowers, A.A. | | Deposit date: | 2017-05-22 | | Release date: | 2017-06-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.411 Å) | | Cite: | P450-Mediated Non-natural Cyclopropanation of Dehydroalanine-Containing Thiopeptides.
ACS Chem. Biol., 12, 2017
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5VVK
 | | Cas1-Cas2 bound to full-site mimic | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*CP*CP*AP*CP*CP*AP*GP*TP*G)-3'), ... | | Authors: | Wright, A.V, Knott, G.J, Doxzen, K.D, Doudna, J.A. | | Deposit date: | 2017-05-19 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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5W0I
 | | CREBBP Bromodomain in complex with Cpd8 (1-(3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one) | | Descriptor: | 1-{3-[7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-1-[(3S)-oxolan-3-yl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one, CREB-binding protein, DIMETHYL SULFOXIDE, ... | | Authors: | Murray, J.M. | | Deposit date: | 2017-05-30 | | Release date: | 2018-03-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
J. Med. Chem., 60, 2017
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5VVJ
 | | Cas1-Cas2 bound to half-site intermediate | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (112-MER), ... | | Authors: | Wright, A.V, Knott, G.J, Doxzen, K.W, Doudna, J.A. | | Deposit date: | 2017-05-19 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.89 Å) | | Cite: | Structures of the CRISPR genome integration complex.
Science, 357, 2017
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4GEL
 | | Crystal structure of Zucchini | | Descriptor: | 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, PHOSPHATE ION, ... | | Authors: | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | | Deposit date: | 2012-08-02 | | Release date: | 2012-10-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.756 Å) | | Cite: | Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
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4G6W
 | | Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol | | Descriptor: | 4-bromobenzene-1,2,3-triol, SULFATE ION, Thymidylate synthase | | Authors: | Celeste, L.R, Lebioda, L. | | Deposit date: | 2012-07-19 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin
To be Published, 2012
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6RAZ
 | | D. melanogaster CMG-DNA, State 2B | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | | Authors: | Eickhoff, P, Martino, F, Costa, A. | | Deposit date: | 2019-04-08 | | Release date: | 2019-09-18 | | Last modified: | 2021-01-20 | | Method: | ELECTRON MICROSCOPY (4.46 Å) | | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.
Cell Rep, 28, 2019
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4GEN
 | | Crystal structure of Zucchini (monomer) | | Descriptor: | CHLORIDE ION, Mitochondrial cardiolipin hydrolase | | Authors: | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | | Deposit date: | 2012-08-02 | | Release date: | 2012-10-17 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
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6OVG
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4GEM
 | | Crystal structure of Zucchini (K171A) | | Descriptor: | 1,2-ETHANEDIOL, Mitochondrial cardiolipin hydrolase, ZINC ION | | Authors: | Nishimasu, H, Fukuhara, S, Ishitani, R, Nureki, O. | | Deposit date: | 2012-08-02 | | Release date: | 2012-10-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.206 Å) | | Cite: | Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
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6P4V
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6P07
 | | Spastin hexamer in complex with substrate | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Sandate, C.R, Szyk, A, Zehr, E, Roll-Mecak, A, Lander, G.C. | | Deposit date: | 2019-05-16 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | An allosteric network in spastin couples multiple activities required for microtubule severing.
Nat.Struct.Mol.Biol., 26, 2019
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