8DJK
 
 | | HMGCR-UBIAD1 Complex State 2 | | Descriptor: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, CHOLESTEROL HEMISUCCINATE, Digitonin, ... | | Authors: | Chen, H, Qi, X, Li, X. | | Deposit date: | 2022-06-30 | | Release date: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain.
Nat Commun, 13, 2022
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5OM9
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with a thiirane mechanism-based inhibitor | | Descriptor: | (2~{R})-4-methyl-2-[(1~{S})-1-sulfanylethyl]pentanoic acid, Carboxypeptidase A1, ZINC ION | | Authors: | Gallego, P, Granados, C, Fernandez, D, Pallares, I, Covaleda, G, Aviles, F.X, Vendrell, J, Reverter, D. | | Deposit date: | 2017-07-28 | | Release date: | 2017-08-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.
ACS Med Chem Lett, 8, 2017
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3ZO1
 | | The Synthesis and Evaluation of Diazaspirocyclic Protein Kinase Inhibitors | | Descriptor: | 6-(1,9-DIAZASPIRO[5.5]UNDECAN-9-YL)-9H-PURINE, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ... | | Authors: | Allen, C.E, Chow, C.L, Caldwell, J.J, Westwood, I.M, van Montfort, R.L, Collins, I. | | Deposit date: | 2013-02-20 | | Release date: | 2013-03-06 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Synthesis and evaluation of heteroaryl substituted diazaspirocycles as scaffolds to probe the ATP-binding site of protein kinases.
Bioorg. Med. Chem., 21, 2013
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7U97
 | | SAAV pH 4.0 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.66 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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7U95
 | | SAAV pH 6.0 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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7U96
 | | SAAV pH 5.5 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.14 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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7U94
 | | SAAV pH 7.4 capsid structure | | Descriptor: | Capsid protein | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2022-03-10 | | Release date: | 2022-04-13 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
J.Virol., 96, 2022
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2AZD
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4K3H
 | | Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green | | Descriptor: | 4-{bis[4-(dimethylamino)phenyl]methyl}phenol, GLYCEROL, Immunoglobulin lambda variable domain L5(L89S), ... | | Authors: | Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A. | | Deposit date: | 2013-04-10 | | Release date: | 2013-10-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
J.Mol.Biol., 425, 2013
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7VAX
 | | V1EG of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state1-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAI
 | | V1EG of V/A-ATPase from Thermus thermophilus, state1-1 | | Descriptor: | V-type ATP synthase alpha chain, V-type ATP synthase beta chain, V-type ATP synthase subunit D, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAP
 | | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state2-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAL
 | | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state1-1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAT
 | | V1EG of V/A-ATPase from Thermus thermophilus at low ATP concentration, state2-1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAW
 | | V1EG domain of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state1-1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAK
 | | Nucleotide-free V1EG domain of V/A-ATPase from Thermus thermophilus, state2 | | Descriptor: | V-type ATP synthase alpha chain, V-type ATP synthase beta chain, V-type ATP synthase subunit D, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAJ
 | | Nucleotide-free V1EG domain of V/A-ATPase from Thermus thermophilus, state1-2 | | Descriptor: | V-type ATP synthase alpha chain, V-type ATP synthase beta chain, V-type ATP synthase subunit D, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAM
 | | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state1-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAN
 | | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state2-1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAQ
 | | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state3-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAS
 | | V1EG domain of V/A-ATPase from Thermus thermophilus at low ATP concentration, state1-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VB0
 | | V1EG domain of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAV
 | | V1EG of V/A-ATPase from Thermus thermophilus at low ATP concentration, state3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAO
 | | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state2-2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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7VAR
 | | V1EG domain of V/A-ATPase from Thermus thermophilus at low ATP concentration, state1-1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | | Deposit date: | 2021-08-30 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
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