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8OUW
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BU of 8ouw by Molmil
Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans)
Descriptor: Cell division control protein 45 homolog, DNA Lagging Strand Template, DNA Leading Strand Template, ...
Authors:Jenkyn-Bedford, M, Yeeles, J.T.P, Labib, K.P.M.
Deposit date:2023-04-25
Release date:2023-08-16
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans.
Science, 381, 2023
4KHN
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BU of 4khn by Molmil
Crystal structure of the ternary complex of the D714A mutant of RB69 DNA polymerase
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ...
Authors:Guja, K.E, Jacewicz, A, Trzemecka, A, Plochocka, D, Yakubovskaya, E, Bebenek, A, Garcia-Diaz, M.
Deposit date:2013-04-30
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Remote Palm Domain Residue of RB69 DNA Polymerase Is Critical for Enzyme Activity and Influences the Conformation of the Active Site.
Plos One, 8, 2013
8TLL
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BU of 8tll by Molmil
CDCA7 (Mouse) Binds Non-B-form 26-mer DNA oligo
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (26-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLJ
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BU of 8tlj by Molmil
CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo Containing a 5mC
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLK
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BU of 8tlk by Molmil
CDCA7 (Human) Binds Non-B-form 32-mer DNA oligo Containing a 5mC
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLH
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BU of 8tlh by Molmil
CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLG
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BU of 8tlg by Molmil
CDCA7 (Mouse) Binds Non-B-form 34-mer DNA oligo
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (34-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
1RAM
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BU of 1ram by Molmil
A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65)
Authors:Chen, Y.-Q, Ghosh, S, Ghosh, G.
Deposit date:1997-11-22
Release date:1998-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel DNA recognition mode by the NF-kappa B p65 homodimer.
Nat.Struct.Biol., 5, 1998
4M3W
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BU of 4m3w by Molmil
RB69 DNA polymerase ternary complex with dT/dG at position n-4 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M3Z
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BU of 4m3z by Molmil
RB69 DNA polymerase ternary complex with dG/dT at position n-2 of primer/tempLate duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M41
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BU of 4m41 by Molmil
RB69 DNA polymerase ternary complex with dG/dT at position n-3 of primer/tempLate duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M3X
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BU of 4m3x by Molmil
RB69 DNA polymerase ternary complex with dT/dG at position n-5 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M42
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BU of 4m42 by Molmil
RB69 DNA polymerase ternary complex with dG/dT at position n-4 of primer/tempLate duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
2ITL
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BU of 2itl by Molmil
The origin binding domain of the SV40 large T antigen bound to the functional pen palindrome DNA (23 bp)
Descriptor: 24-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Bochkareva, E, Seitova, A, Bochkarev, A.
Deposit date:2006-10-19
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
Embo J., 25, 2006
3CFR
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BU of 3cfr by Molmil
Structure of the replicating complex of a POL Alpha family DNA Polymerase, ternary complex 2
Descriptor: CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*(DOC))-3'), ...
Authors:Wang, J, Klimenko, D, Wang, M, Steitz, T.A, Konigsberg, W.H.
Deposit date:2008-03-04
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into base selectivity from the structures of an RB69 DNA Polymerase triple mutant
To be Published
4M3R
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BU of 4m3r by Molmil
RB69 DNA polymerase ternary complex with dT/dG at position n-1 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M45
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BU of 4m45 by Molmil
RB69 DNA polymerase ternary complex with dG/dT at position n-5 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M3U
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BU of 4m3u by Molmil
RB69 DNA polymerase ternary complex with dT/dG at position n-3 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M3T
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BU of 4m3t by Molmil
RB69 DNA polymerase ternary complex with dT/dG at position n-2 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
4M3Y
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BU of 4m3y by Molmil
RB69 DNA polymerase ternary complex with dG/dT at position n-1 of primer/template duplex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ...
Authors:Xia, S, Konigsberg, W.H.
Deposit date:2013-08-06
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.
Protein Sci., 23, 2014
3EYZ
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BU of 3eyz by Molmil
Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA (open form)
Descriptor: 5'-D(*DAP*DTP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DAP*DGP*DGP*DA)-3', 5'-D(*DCP*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DGP*DC)-3', DNA polymerase I, ...
Authors:Warren, J.J, Wu, E.Y, Golosov, A.A, Karplus, M, Beese, L.S.
Deposit date:2008-10-22
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis.
Structure, 18, 2010
5MGA
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BU of 5mga by Molmil
Structure of the Cpf1 endonuclease R-loop complex after DNA cleavage
Descriptor: CRISPR-associated endonuclease Cpf1, DNA (26-MER), DNA (5'-D(P*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), ...
Authors:Montoya, G, Stella, S.
Deposit date:2016-11-21
Release date:2017-06-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.
Nature, 546, 2017
1WYW
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BU of 1wyw by Molmil
Crystal Structure of SUMO1-conjugated thymine DNA glycosylase
Descriptor: CHLORIDE ION, G/T mismatch-specific thymine DNA glycosylase, MAGNESIUM ION, ...
Authors:Baba, D, Maita, N, Jee, J.G, Uchimura, Y, Saitoh, H, Sugasawa, K, Hanaoka, F, Tochio, H, Hiroaki, H, Shirakawa, M.
Deposit date:2005-02-17
Release date:2005-06-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of thymine DNA glycosylase conjugated to SUMO-1.
Nature, 435, 2005
1C0W
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BU of 1c0w by Molmil
CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
Descriptor: COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), ...
Authors:Pohl, E, Holmes, R.K, Hol, W.G.
Deposit date:1999-07-22
Release date:2000-07-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
J.Mol.Biol., 292, 1999
4FLT
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BU of 4flt by Molmil
Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, GLYCEROL, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2012-06-15
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
J.Mol.Biol., 423, 2012

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