7NKC
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207 | Descriptor: | Nb8207, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-17 | Release date: | 2021-12-01 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (4.46 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NHC
| 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-10 | Release date: | 2021-12-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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5HJB
| AF9 YEATS in complex with histone H3 Crotonylation at K9 | Descriptor: | Protein AF-9, peptide of Histone H3.1 | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-12 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain Mol.Cell, 62, 2016
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7NIL
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core | Descriptor: | Nanobody8190 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | Authors: | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | Deposit date: | 2021-02-12 | Release date: | 2021-12-01 | Last modified: | 2022-02-09 | Method: | ELECTRON MICROSCOPY (5.01 Å) | Cite: | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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5HJD
| AF9 YEATS in complex with histone H3 Crotonylation at K18 | Descriptor: | COPPER (II) ION, Protein AF-9, SULFATE ION, ... | Authors: | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | Deposit date: | 2016-01-13 | Release date: | 2016-04-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Mol.Cell, 62, 2016
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8RH3
| Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT bound to Gemcitabine | Descriptor: | (2~{R},3~{R})-4,4-bis(fluoranyl)-2-(hydroxymethyl)oxolan-3-ol, Nucleoside 2-deoxyribosyltransferase | Authors: | Tang, P, Harding, C.J, Czekster, C.M. | Deposit date: | 2023-12-14 | Release date: | 2024-02-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis, 14, 2024
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5Y4U
| Crystal structure of Grx domain of Grx3 from Saccharomyces cerevisiae | Descriptor: | Monothiol glutaredoxin-3 | Authors: | Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2017-08-05 | Release date: | 2018-08-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3. J.Mol.Biol., 430, 2018
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6VDP
| Crystal structure of SfmD truncated variant | Descriptor: | 3-methyl-L-tyrosine peroxygenase, HEME C | Authors: | Shin, I, Liu, A. | Deposit date: | 2019-12-27 | Release date: | 2021-03-10 | Last modified: | 2021-07-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis -His ligand set revealed by a de novo crystal structural and spectroscopic study. Chem Sci, 12, 2021
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6VDZ
| Crystal structure of reduced SfmD by soaking with sodium hydrosulfite | Descriptor: | 3-methyl-L-tyrosine peroxygenase, HEME C | Authors: | Shin, I, Liu, A. | Deposit date: | 2019-12-27 | Release date: | 2021-03-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis -His ligand set revealed by a de novo crystal structural and spectroscopic study. Chem Sci, 12, 2021
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5IZS
| De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | Descriptor: | Designed protein 5L6HC3_1 | Authors: | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Oberdorfer, G. | Deposit date: | 2016-03-25 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
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6VE0
| Crystal structure of reduced SfmD by soaking with sodium hydrosulfite | Descriptor: | 3-methyl-L-tyrosine peroxygenase, HEME C | Authors: | Shin, I, Liu, A. | Deposit date: | 2019-12-27 | Release date: | 2021-03-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis -His ligand set revealed by a de novo crystal structural and spectroscopic study. Chem Sci, 12, 2021
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6WDR
| Subunit joining exposes nascent pre-40S rRNA for processing and quality control | Descriptor: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S10-A, ... | Authors: | Rai, J, Parker, M.D, Huang, H, Choy, S, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E. | Deposit date: | 2020-04-01 | Release date: | 2020-09-30 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7. Rna, 27, 2021
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6VDQ
| Crystal structure of SfmD | Descriptor: | 3-methyl-L-tyrosine peroxygenase, HEME C | Authors: | Shin, I, Liu, A. | Deposit date: | 2019-12-27 | Release date: | 2021-03-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis -His ligand set revealed by a de novo crystal structural and spectroscopic study. Chem Sci, 12, 2021
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5J0K
| De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity | Descriptor: | designed protein 2L4HC2_23 | Authors: | Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. | Deposit date: | 2016-03-28 | Release date: | 2016-05-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
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8E1K
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8DZX
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6ZQE
| Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | Deposit date: | 2020-07-09 | Release date: | 2020-09-23 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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8E3H
| Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, Mg-ADP-BeF3, and NusG; Rho hexamer part | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Molodtsov, V, Wang, C. | Deposit date: | 2022-08-17 | Release date: | 2022-09-07 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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5Y2W
| Structure of Synechocystis PCC6803 CcmR regulatory domain in complex with 2-PG | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, Rubisco operon transcriptional regulator | Authors: | Jiang, Y.L, Wang, X.P, Sun, H, Cheng, W, Cao, D.D, Han, S.J, Li, W.F, Chen, Y, Zhou, C.Z. | Deposit date: | 2017-07-27 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Coordinating carbon and nitrogen metabolic signaling through the cyanobacterial global repressor NdhR. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8E09
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8DZY
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7M0X
| Crystal structure of the BRAF:MEK1 kinases in complex with AMPPNP and PD0325901 | Descriptor: | CHLORIDE ION, Dual specificity mitogen-activated protein kinase kinase 1, GLYCEROL, ... | Authors: | Li, K, Gonzalez Del-Pino, G, Ha, B.H, Park, E, Eck, M.J. | Deposit date: | 2021-03-11 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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5HLY
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8E03
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5F8G
| Enterovirus 71 Polymerase Elongation Complex (C1S1 Form) | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... | Authors: | Shu, B, Gong, P. | Deposit date: | 2015-12-09 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016
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