8Q8X
 
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2M58
 | | Structure of 2'-5' AG1 lariat forming ribozyme in its inactive state | | Descriptor: | RNA (59-MER) | | Authors: | Carlomagno, T, Amata, I, Codutti, L, Falb, M, Fohrer, J, Simon, B. | | Deposit date: | 2013-02-18 | | Release date: | 2013-04-03 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme.
J.Am.Chem.Soc., 135, 2013
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7QJW
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7L1S
 | | PS3 F1-ATPase Pi-bound Dwell | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ATP synthase subunit alpha, ... | | Authors: | Sobti, M, Ueno, H, Noji, H, Stewart, A.G. | | Deposit date: | 2020-12-15 | | Release date: | 2021-07-21 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The six steps of the complete F 1 -ATPase rotary catalytic cycle.
Nat Commun, 12, 2021
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7TCP
 | | Structure of Xenopus KCNQ1-CaM | | Descriptor: | CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1 | | Authors: | Willegems, K, Kyriakis, E, Van Petegem, F, Eldstrom, J, Fedida, D. | | Deposit date: | 2021-12-27 | | Release date: | 2022-07-06 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Structural and electrophysiological basis for the modulation of KCNQ1 channel currents by ML277.
Nat Commun, 13, 2022
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8Q9B
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7B62
 | | Crystal structure of SARS-CoV-2 spike protein N-terminal domain in complex with biliverdin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Pye, V.E, Rosa, A, Roustan, C, Cherepanov, P. | | Deposit date: | 2020-12-07 | | Release date: | 2021-04-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Sci Adv, 7, 2021
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7EN3
 | | Crystal structure of tubulin in complex with Tubulysin analogue TGL | | Descriptor: | (2S,4R)-5-(4-fluorophenyl)-2-methyl-4-[[2-[(1R,3R)-4-methyl-3-[5-methylhexyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-1-oxidanyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Wang, Y, Li, W. | | Deposit date: | 2021-04-15 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.643 Å) | | Cite: | The X-ray structure of tubulysin analogue TGL in complex with tubulin and three possible routes for the development of next-generation tubulysin analogues.
Biochem.Biophys.Res.Commun., 565, 2021
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7L1Q
 | | PS3 F1-ATPase Binding/TS Dwell | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Sobti, M, Ueno, H, Noji, H, Stewart, A.G. | | Deposit date: | 2020-12-15 | | Release date: | 2021-07-21 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | The six steps of the complete F 1 -ATPase rotary catalytic cycle.
Nat Commun, 12, 2021
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5KLU
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7AYG
 | | oxalyl-CoA decarboxylase from Methylorubrum extorquens with bound TPP and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative oxalyl-CoA decarboxylase (Oxc, ... | | Authors: | Pfister, P, Burgener, S, Nattermann, M, Zarzycki, J, Erb, T.J. | | Deposit date: | 2020-11-12 | | Release date: | 2021-04-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism.
Acs Catalysis, 11, 2021
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7EA1
 | | Crystal Structure of Spindlin1 bound to SPINDOC Docpep2 | | Descriptor: | Peptide from Spindlin interactor and repressor of chromatin-binding protein, Spindlin-1 | | Authors: | Zhao, F, Li, H. | | Deposit date: | 2021-03-05 | | Release date: | 2022-06-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular basis for SPINDOC-Spindlin1 engagement and its role in transcriptional inhibition
to be published
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2M1L
 | | Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2, DOC-1R) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8910C | | Descriptor: | Cyclin-dependent kinase 2-associated protein 2 | | Authors: | Ertekin, A, Janjua, H, Kohan, E, Shastry, R, Pederson, K, Prestegard, J.H, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-11-30 | | Release date: | 2013-01-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of CDK2-associated protein 2 (CDK2AP2, Deleted in Oral Cancer 1 Related protein, DOC-1R)
To be Published
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7AUE
 | | Melanocortin receptor 4 (MC4R) Gs protein complex | | Descriptor: | AMINOSERINE, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Degtjarik, O, Israeli, H, Prabahar, V, Shalev-Benami, M. | | Deposit date: | 2020-11-02 | | Release date: | 2021-04-28 | | Last modified: | 2023-03-15 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.
Science, 372, 2021
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7B2E
 | | quadruple mutant of oxalyl-CoA decarboxylase from Methylorubrum extorquens with bound TPP and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative oxalyl-CoA decarboxylase (Oxc, ... | | Authors: | Pfister, P, Burgener, S, Nattermann, M, Zarzycki, J, Erb, T.J. | | Deposit date: | 2020-11-26 | | Release date: | 2021-04-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism.
Acs Catalysis, 11, 2021
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2M6V
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7L1R
 | | PS3 F1-ATPase Hydrolysis Dwell | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | | Authors: | Sobti, M, Ueno, H, Noji, H, Stewart, A.G. | | Deposit date: | 2020-12-15 | | Release date: | 2021-07-21 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The six steps of the complete F 1 -ATPase rotary catalytic cycle.
Nat Commun, 12, 2021
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8Q3N
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8Q3P
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3IUC
 | | Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 5 (Glucose-regulated protein, ... | | Authors: | Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-08-31 | | Release date: | 2009-09-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
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8PEJ
 | | CjGH35 with a Galactosidase Activity-Based Probe | | Descriptor: | (1~{S},2~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, ACETATE ION, Beta-galactosidase, ... | | Authors: | Offen, W.A, Davies, G.J. | | Deposit date: | 2023-06-14 | | Release date: | 2023-10-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The development of a broad-spectrum retaining beta-exo-galactosidase activity-based probe.
Org.Biomol.Chem., 21, 2023
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7E9F
 | | Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome | | Descriptor: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | | Authors: | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | | Deposit date: | 2021-03-04 | | Release date: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
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8PO9
 | | Polyethylene oxidation hexamerin PEase Cibeles (XP_026756460) from Galleria mellonella | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Arylphorin, ... | | Authors: | Illanes-Vicioso, R, Ruiz-Lopez, E, Sola, M, Bertocchini, F, Palomo, E.A. | | Deposit date: | 2023-07-03 | | Release date: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Plastic degradation by insect hexamerins: Near-atomic resolution structures of the polyethylene-degrading proteins from the wax worm saliva.
Sci Adv, 9, 2023
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2M3M
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7Q5R
 | | Protein community member pyruvate dehydrogenase complex E2 core from C. thermophilum | | Descriptor: | Acetyltransferase component of pyruvate dehydrogenase complex | | Authors: | Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. | | Deposit date: | 2021-11-04 | | Release date: | 2022-02-02 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Cryo-EM and artificial intelligence visualize endogenous protein community members.
Structure, 30, 2022
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