8XCQ
 
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8XD0
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8XCU
 | | Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH, AKG and GLU in the steady stage of reaction | | Descriptor: | 2-OXOGLUTARIC ACID, GAMMA-L-GLUTAMIC ACID, Glutamate dehydrogenase, ... | | Authors: | Wakabayashi, T, Oide, M, Nakasako, M. | | Deposit date: | 2023-12-10 | | Release date: | 2023-12-27 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
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8XD1
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8XD5
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8XD2
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8XCP
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8XCO
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8XCS
 | | Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus in complex with NADPH, AKG and NH4 in the initial stage of reaction | | Descriptor: | 2-OXOGLUTARIC ACID, AMMONIUM ION, Glutamate dehydrogenase, ... | | Authors: | Wakabayashi, T, Oide, M, Nakasako, M. | | Deposit date: | 2023-12-10 | | Release date: | 2023-12-27 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
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8XCT
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8XCY
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7SG4
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8XCZ
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8XD3
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8XD6
 | | Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus in complex with NADPH, AKG and NH4 in the steady stage of reaction | | Descriptor: | 2-OXOGLUTARIC ACID, AMMONIUM ION, Glutamate dehydrogenase, ... | | Authors: | Wakabayashi, T, Oide, M, Nakasako, M. | | Deposit date: | 2023-12-10 | | Release date: | 2023-12-27 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
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8WA9
 | | Human transketolase soaked with donor ketose D-fructose | | Descriptor: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Liu, Z, Tittmann, K, Dai, S. | | Deposit date: | 2023-09-07 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024
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8WRK
 | | glycosyltransferase UGT74AN3 | | Descriptor: | Glycosyltransferase, PICEATANNOL, URIDINE-5'-DIPHOSPHATE | | Authors: | Huang, W, Long, F. | | Deposit date: | 2023-10-15 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Substrate Promiscuity, Crystal Structure, and Application of a Plant UDP-Glycosyltransferase UGT74AN3
Acs Catalysis, 14, 2024
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8WA7
 | | E.coli transketolase soaked with donor ketose D-fructose | | Descriptor: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, ... | | Authors: | Liu, Z, Dai, S, Tittmann, K. | | Deposit date: | 2023-09-07 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024
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7RZ3
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8WAA
 | | Human transketolase soaked with donor ketose D-xylulose | | Descriptor: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Liu, Z, Dai, S, Tittmann, K. | | Deposit date: | 2023-09-07 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024
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8TYL
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7S84
 | | Crystal structure of CDK2 liganded with compound TW8972 | | Descriptor: | 2-{[2-(1H-indol-3-yl)ethyl]amino}-5-(trifluoromethyl)benzoic acid, Cyclin-dependent kinase 2 | | Authors: | Sun, L, Schonbrunn, E. | | Deposit date: | 2021-09-17 | | Release date: | 2022-09-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.
Nat Commun, 14, 2023
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8UH1
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8WSM
 | | NLRP3 NACHT domain in complex with compound 32 | | Descriptor: | 2-[[2-methyl-5-(trifluoromethyl)phenyl]amino]-~{N}-(1,4-oxazepan-4-ylsulfonyl)-1,3-oxazole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Akai, S, Orita, T, Adachi, T. | | Deposit date: | 2023-10-17 | | Release date: | 2023-11-22 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Discovery of Novel NLRP3 Inflammasome Inhibitors Composed of an Oxazole Scaffold Bearing an Acylsulfamide.
Acs Med.Chem.Lett., 14, 2023
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7SJS
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