PDB: 26577 resultsInfo pagesStatus searchChemie searchBIRD

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3G69	The crystal structure of Streptococcus pneumoniae Sortase C provides novel insights into catalysis as well as pilin substrate specificity Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, Sortase C Authors: Neiers, F, Madhurantakam, C, Falker, S, Manzano, C, Dessen, A, Normark, S, Henriques-Normark, B, Achour, A. Deposit date: 2009-02-06 Release date: 2009-09-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity. J.Mol.Biol., 393, 2009
3I0Z	Crystal structure of putative putative tagatose-6-phosphate ketose/aldose isomerase (NP_344614.1) from STREPTOCOCCUS PNEUMONIAE TIGR4 at 1.70 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2009-06-25 Release date: 2009-07-14 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of putative putative tagatose-6-phosphate ketose/aldose isomerase (NP_344614.1) from STREPTOCOCCUS PNEUMONIAE TIGR4 at 1.70 A resolution To be published
4A34	Crystal structure of the fucose mutarotase in complex with L-fucose from Streptococcus pneumoniae Descriptor: POTASSIUM ION, RBSD/FUCU TRANSPORT PROTEIN FAMILY PROTEIN, beta-L-fucopyranose Authors: Higgins, M.A, Boraston, A.B. Deposit date: 2011-09-29 Release date: 2011-10-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the Fucose Mutarotase from Streptococcus Pneumoniae in Complex with L-Fucose Acta Crystallogr.,Sect.F, 67, 2011
4YW2	Crystal Structure of Streptococcus pneumoniae NanC, complex 6'SL Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... Authors: Owen, C.D, Lukacik, P, Potter, J.A, Walsh, M, Taylor, G.L. Deposit date: 2015-03-20 Release date: 2015-09-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YZ5	Crystal Structure of Streptococcus pneumoniae NanC, in complex with 3-Sialyllactose Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, Putative neuraminidase, ... Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2015-09-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
4YZ4	Crystal Structure of Streptococcus pneumoniae NanC, in complex with N-Acetylneuraminic acid. Descriptor: N-acetyl-alpha-neuraminic acid, SULFATE ION, Sialidase, ... Authors: Lukacik, P, Owen, C.D, Potter, J.A, Taylor, G.L, Walsh, M.A. Deposit date: 2015-03-24 Release date: 2015-09-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Streptococcus pneumoniae NanC: STRUCTURAL INSIGHTS INTO THE SPECIFICITY AND MECHANISM OF A SIALIDASE THAT PRODUCES A SIALIDASE INHIBITOR. J.Biol.Chem., 290, 2015
6UZ4	Solution structure of AGL55-Kringle 2 complex Descriptor: M protein, Plasminogen Authors: Qiu, C, Yuan, Y, Castellino, F.J. Deposit date: 2019-11-14 Release date: 2020-12-09 Method: SOLUTION NMR Cite: Structural evolution of the A-domain in plasminogen-binding Group A streptococcal M-protein reflects improved adaptability of the pathogen to the host To Be Published
6S5Z	Structure of Rib R28N from Streptococcus pyogenes Descriptor: SODIUM ION, Surface protein R28 Authors: Whelan, F, Griffiths, S.C, Whittingham, J.L, Bateman, A, Potts, J.R. Deposit date: 2019-07-02 Release date: 2019-12-11 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection. Proc.Natl.Acad.Sci.USA, 116, 2019
5XBL	Structure of nuclease in complex with associated protein Descriptor: Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER) Authors: Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z. Deposit date: 2017-03-20 Release date: 2017-06-14 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.052 Å) Cite: Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein Nature, 546, 2017
1NSJ	CRYSTAL STRUCTURE OF PHOSPHORIBOSYL ANTHRANILATE ISOMERASE FROM THERMOTOGA MARITIMA Descriptor: PHOSPHATE ION, PHOSPHORIBOSYL ANTHRANILATE ISOMERASE Authors: Hennig, M, Jansonius, J.N.J. Deposit date: 1996-09-13 Release date: 1997-03-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure at 2.0 A resolution of phosphoribosyl anthranilate isomerase from the hyperthermophile Thermotoga maritima: possible determinants of protein stability. Biochemistry, 36, 1997
4ZT9	Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA Authors: Jiang, F, Doudna, J.A. Deposit date: 2015-05-14 Release date: 2015-07-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: A Cas9-guide RNA complex preorganized for target DNA recognition. Science, 348, 2015
4ZT0	Crystal structure of catalytically-active Streptococcus pyogenes Cas9 in complex with single-guide RNA at 2.9 Angstrom resolution Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA Authors: Jiang, F, Doudna, J.A. Deposit date: 2015-05-14 Release date: 2015-07-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Cas9-guide RNA complex preorganized for target DNA recognition. Science, 348, 2015
5XJ1	Crystal structure of spRlmCD Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HEXAETHYLENE GLYCOL, ... Authors: Jiang, Y, Gong, Q. Deposit date: 2017-04-28 Release date: 2017-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.753 Å) Cite: Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD PLoS ONE, 12, 2017
4AZ6	Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH Descriptor: 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, BETA-N-ACETYLHEXOSAMINIDASE, ... Authors: Pluvinage, B, Stubbs, K.A, Vocadlo, D.J, Boraston, A.B. Deposit date: 2012-06-23 Release date: 2013-07-10 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11, 2013
3O92	High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes Descriptor: ZINC ION, nicotinamidase Authors: French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E. Deposit date: 2010-08-03 Release date: 2011-01-12 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes . Biochemistry, 49, 2010
4AZ7	Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH Descriptor: 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, BETA-N-ACETYLHEXOSAMINIDASE, ... Authors: Pluvinage, B, Stubbs, K.A, Vocadlo, D.J, Boraston, A.B. Deposit date: 2012-06-23 Release date: 2013-07-10 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11, 2013
4AZH	Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH Descriptor: 1,2-ETHANEDIOL, BETA-N-ACETYLHEXOSAMINIDASE, N-acetylglucosaminono-1,5-lactone (Z)-oxime Authors: Pluvinage, B, Stubbs, K.A, Vocadlo, D.J, Boraston, A.B. Deposit date: 2012-06-26 Release date: 2013-07-10 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11, 2013
4AZG	Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH Descriptor: 1,2-ETHANEDIOL, ACETATE ION, BETA-N-ACETYLHEXOSAMINIDASE, ... Authors: Pluvinage, B, Stubbs, K.A, Vocadlo, D.J, Boraston, A.B. Deposit date: 2012-06-25 Release date: 2013-07-10 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11, 2013
4B3L	Family 1 6-phospho-beta-D glycosidase from Streptococcus pyogenes Descriptor: BETA-GLUCOSIDASE Authors: Stepper, J, Dabin, J, Ekloef, J.M, Thongpoo, P, Kongsaeree, P.T, Taylor, E.J, Turkenburg, J.P, Brumer, H, Davies, G.J. Deposit date: 2012-07-24 Release date: 2013-01-09 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Structure and Activity of the Streptococcus Pyogenes Family Gh1 6-Phospho Beta-Glycosidase Spy1599 Acta Crystallogr.,Sect.D, 69, 2013
3GE2	Crystal structure of putative lipoprotein SP_0198 from Streptococcus pneumoniae Descriptor: CHLORIDE ION, GLYCEROL, Lipoprotein, ... Authors: Kim, Y, Zhang, R, Joachimiak, G, Gornicki, P, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2009-02-24 Release date: 2009-03-17 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (2.203 Å) Cite: Crystal Structure of Putative Lipoprotein SP_0198 from Streptococcus pneumoniae To be Published
5HUO	Crystal Structure of NadC Deletion Mutant in C2221 Space Group Descriptor: Nicotinate-nucleotide diphosphorylase (Carboxylating), SULFATE ION Authors: Booth, W.T, Chruszcz, M. Deposit date: 2016-01-27 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD(+) synthetase. FEBS J., 284, 2017
3GO5	Crystal structure of a multidomain protein with nucleic acid binding domains (sp_0946) from streptococcus pneumoniae tigr4 at 1.40 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Multidomain protein with S1 RNA-binding domains Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2009-03-18 Release date: 2009-04-07 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module. Structure, 18, 2010
5XJ2	Structure of spRlmCD with U747 RNA Descriptor: RNA (5'-R(*GP*GP*CP*AP*CP*GP*UP*GP*CP*U)-3'), S-ADENOSYL-L-HOMOCYSTEINE, Uncharacterized RNA methyltransferase SP_1029, ... Authors: Jiang, Y, Gong, Q. Deposit date: 2017-04-28 Release date: 2017-11-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.84 Å) Cite: Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD PLoS ONE, 12, 2017
3OP1	Crystal Structure of Macrolide-efflux Protein SP_1110 from Streptococcus pneumoniae Descriptor: ACETIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Kim, Y, Li, H, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2010-08-31 Release date: 2010-09-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.488 Å) Cite: Crystal Structure of Macrolide-efflux Protein SP_1110 from Streptococcus pneumoniae TO BE PUBLISHED
4Z9X	Crystal structure of 2-keto-3-deoxy-D-gluconate dehydrogenase from Streptococcus pyogenes Descriptor: Gluconate 5-dehydrogenase Authors: Maruyama, Y, Takase, R, Oiki, S, Mikami, B, Murata, K, Hashimoto, W. Deposit date: 2015-04-13 Release date: 2015-04-29 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural determinants in bacterial 2-keto-3-deoxy-D-gluconate dehydrogenase KduD for dual-coenzyme specificity Proteins, 84, 2016

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