1Y2E
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![BU of 1y2e by Molmil](/molmil-images/mine/1y2e) | Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 1-(4-amino-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester | Descriptor: | 1,2-ETHANEDIOL, 1-(4-AMINOPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ... | Authors: | Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design Nat.Biotechnol., 23, 2005
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1Y2F
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![BU of 1y2f by Molmil](/molmil-images/mine/1y2f) | Crystal Structure of ZipA with an inhibitor | Descriptor: | 4-{2-[4-(2-AMINOETHYL)PIPERAZIN-1-YL]PYRIDIN-4-YL}-N-(3-CHLORO-4-METHYLPHENYL)PYRIMIDIN-2-AMINE, Cell division protein zipA | Authors: | Mosyak, L, Rush, T.S. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction J.Med.Chem., 48, 2005
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1Y2G
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![BU of 1y2g by Molmil](/molmil-images/mine/1y2g) | Crystal STructure of ZipA in complex with an inhibitor | Descriptor: | Cell division protein zipA, N-METHYL-N-[3-(6-PHENYL[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-3-YL)PHENYL]ACETAMIDE | Authors: | Mosyak, L, Rush, T.S. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction J.Med.Chem., 48, 2005
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1Y2H
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![BU of 1y2h by Molmil](/molmil-images/mine/1y2h) | Catalytic Domain Of Human Phosphodiesterase 4B In Complex With 1-(2-chloro-phenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester | Descriptor: | 1-(2-CHLOROPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ZINC ION, ... | Authors: | Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design Nat.Biotechnol., 23, 2005
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1Y2I
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![BU of 1y2i by Molmil](/molmil-images/mine/1y2i) | Crystal Structure of MCSG Target APC27401 from Shigella flexneri | Descriptor: | Hypothetical Protein S0862 | Authors: | Brunzelle, J.S, Minasov, G, Yang, X, Shuvalova, L, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-11-22 | Release date: | 2005-01-04 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of MCSG Target APC27401 from Shigella flexneri To be Published
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1Y2J
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![BU of 1y2j by Molmil](/molmil-images/mine/1y2j) | Catalytic Domain Of Human Phosphodiesterase 4B In Complex With 3,5-dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester | Descriptor: | 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ZINC ION, ... | Authors: | Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design Nat.Biotechnol., 23, 2005
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1Y2K
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![BU of 1y2k by Molmil](/molmil-images/mine/1y2k) | Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1-(3-nitro-phenyl)-1H-pyrazole-4-carboxylic acid ethyl ester | Descriptor: | 1,2-ETHANEDIOL, 3,5-DIMETHYL-1-(3-NITROPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER, MAGNESIUM ION, ... | Authors: | Card, G.L, Blasdel, L, England, B.P, Zhang, C, Suzuki, Y, Gillette, S, Fong, D, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-11-22 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design Nat.Biotechnol., 23, 2005
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1Y2M
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![BU of 1y2m by Molmil](/molmil-images/mine/1y2m) | Crystal structure of phenylalanine ammonia-lyase from yeast Rhododporidium toruloides | Descriptor: | Phenylalanine ammonia-lyase | Authors: | Wang, L, Gamez, A, Sarkissian, C.N, Straub, M, Patch, M.G, Han, G.W, Scriver, C.R, Stevens, R.C. | Deposit date: | 2004-11-22 | Release date: | 2005-11-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria. Mol.Genet.Metab., 86, 2005
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1Y2O
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![BU of 1y2o by Molmil](/molmil-images/mine/1y2o) | Structure of N-terminal domain IRSp53/BAIAP2 | Descriptor: | BAI1-associated protein 2 isoform 1 | Authors: | Millard, T.H, Bompard, G, Heung, M.-Y, Dafforn, T.R, Scott, D.J, Machesky, L.M, Futterer, K. | Deposit date: | 2004-11-23 | Release date: | 2005-02-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53 Embo J., 24, 2005
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1Y2P
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![BU of 1y2p by Molmil](/molmil-images/mine/1y2p) | |
1Y2Q
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![BU of 1y2q by Molmil](/molmil-images/mine/1y2q) | |
1Y2S
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![BU of 1y2s by Molmil](/molmil-images/mine/1y2s) | Ovine Prion Protein Variant R168 | Descriptor: | Major prion protein | Authors: | Christen, B, Lysek, D.A, Herrmann, T, Wuthrich, K. | Deposit date: | 2004-11-23 | Release date: | 2004-12-28 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Prion protein NMR structures of cats, dogs, pigs, and sheep Proc.Natl.Acad.Sci.USA, 102, 2005
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1Y2T
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![BU of 1y2t by Molmil](/molmil-images/mine/1y2t) | Crystal structure of the common edible mushroom (Agaricus bisporus) lectin | Descriptor: | lectin | Authors: | Carrizo, M.E, Capaldi, S, Perduca, M, Irazoqui, F.J, Nores, G.A, Monaco, H.L. | Deposit date: | 2004-11-23 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Antineoplastic Lectin of the Common Edible Mushroom (Agaricus bisporus) Has Two Binding Sites, Each Specific for a Different Configuration at a Single Epimeric Hydroxyl J.Biol.Chem., 280, 2005
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1Y2U
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![BU of 1y2u by Molmil](/molmil-images/mine/1y2u) | Crystal structure of the common edible mushroom (Agaricus bisporus) lectin in complex with Lacto-N-biose | Descriptor: | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, lectin | Authors: | Carrizo, M.E, Capaldi, S, Perduca, M, Irazoqui, F.J, Nores, G.A, Monaco, H.L. | Deposit date: | 2004-11-23 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Antineoplastic Lectin of the Common Edible Mushroom (Agaricus bisporus) Has Two Binding Sites, Each Specific for a Different Configuration at a Single Epimeric Hydroxyl J.Biol.Chem., 280, 2005
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1Y2V
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![BU of 1y2v by Molmil](/molmil-images/mine/1y2v) | Crystal structure of the common edible mushroom (Agaricus bisporus) lectin in complex with T-antigen | Descriptor: | SERINE, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, lectin | Authors: | Carrizo, M.E, Capaldi, S, Perduca, M, Irazoqui, F.J, Nores, G.A, Monaco, H.L. | Deposit date: | 2004-11-23 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Antineoplastic Lectin of the Common Edible Mushroom (Agaricus bisporus) Has Two Binding Sites, Each Specific for a Different Configuration at a Single Epimeric Hydroxyl J.Biol.Chem., 280, 2005
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1Y2W
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![BU of 1y2w by Molmil](/molmil-images/mine/1y2w) | Crystal structure of the orthorhombic form of the common edible mushroom (Agaricus bisporus) lectin in complex with T-antigen and N-acetylglucosamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SERINE, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | Authors: | Carrizo, M.E, Capaldi, S, Perduca, M, Irazoqui, F.J, Nores, G.A, Monaco, H.L. | Deposit date: | 2004-11-23 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The Antineoplastic Lectin of the Common Edible Mushroom (Agaricus bisporus) Has Two Binding Sites, Each Specific for a Different Configuration at a Single Epimeric Hydroxyl J.Biol.Chem., 280, 2005
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1Y2X
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![BU of 1y2x by Molmil](/molmil-images/mine/1y2x) | Crystal structure of the tetragonal form of the common edible mushroom (Agaricus bisporus) lectin in complex with T-antigen and N-acetylglucosamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SERINE, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | Authors: | Carrizo, M.E, Capaldi, S, Perduca, M, Irazoqui, F.J, Nores, G.A, Monaco, H.L. | Deposit date: | 2004-11-23 | Release date: | 2004-12-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | The Antineoplastic Lectin of the Common Edible Mushroom (Agaricus bisporus) Has Two Binding Sites, Each Specific for a Different Configuration at a Single Epimeric Hydroxyl J.Biol.Chem., 280, 2005
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1Y2Y
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![BU of 1y2y by Molmil](/molmil-images/mine/1y2y) | Structural Characterization of Nop10p using Nuclear Magnetic Resonance Spectroscopy | Descriptor: | Ribosome biogenesis protein Nop10 | Authors: | Khanna, M, Wu, H, Johansson, C, Caizergues-Ferrer, M, Feigon, J. | Deposit date: | 2004-11-23 | Release date: | 2005-12-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA RNA, 12, 2006
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1Y2Z
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![BU of 1y2z by Molmil](/molmil-images/mine/1y2z) | |
1Y30
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![BU of 1y30 by Molmil](/molmil-images/mine/1y30) | X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with flavin mononucleotide at 2.2 a resolution | Descriptor: | FLAVIN MONONUCLEOTIDE, hypothetical protein Rv1155 | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-11-23 | Release date: | 2005-08-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate. Acta Crystallogr.,Sect.D, 61, 2005
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1Y31
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![BU of 1y31 by Molmil](/molmil-images/mine/1y31) | |
1Y32
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![BU of 1y32 by Molmil](/molmil-images/mine/1y32) | NMR structure of humanin in 30% TFE solution | Descriptor: | Humanin | Authors: | Benaki, D, Zikos, C, Evangelou, A, Livaniou, E, Vlassi, M, Mikros, E, Pelecanou, M. | Deposit date: | 2004-11-23 | Release date: | 2005-02-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of humanin, a peptide against Alzheimer's disease-related neurotoxicity. Biochem.Biophys.Res.Commun., 329, 2005
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1Y33
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![BU of 1y33 by Molmil](/molmil-images/mine/1y33) | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 T58P mutant | Descriptor: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | Deposit date: | 2004-11-23 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
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1Y34
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![BU of 1y34 by Molmil](/molmil-images/mine/1y34) | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60A mutant | Descriptor: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | Deposit date: | 2004-11-23 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
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1Y35
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![BU of 1y35 by Molmil](/molmil-images/mine/1y35) | |