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1TAS	CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE Authors: Hohenester, E, Jansonius, J.N. Deposit date: 1993-10-04 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystalline mitochondrial aspartate aminotransferase exists in only two conformations. J.Mol.Biol., 236, 1994
1V2F	Crystal Structure of T.th HB8 Glutamine Aminotransferase complex with 3-phenylpropionate Descriptor: Glutamine Aminotransferase, HYDROCINNAMIC ACID, PYRIDOXAL-5'-PHOSPHATE Authors: Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2003-10-15 Release date: 2004-07-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition J.BIOL.CHEM., 279, 2004
1V2D	Crystal Structure of T.th HB8 Glutamine Aminotransferase Descriptor: Glutamine Aminotransferase, PYRIDOXAL-5'-PHOSPHATE Authors: Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2003-10-15 Release date: 2004-07-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition J.BIOL.CHEM., 279, 2004
1TOK	Maleic acid-bound structure of SRHEPT mutant of E. coli aspartate aminotransferase Descriptor: Aspartate aminotransferase, MALEIC ACID Authors: Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F. Deposit date: 2004-06-14 Release date: 2004-10-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase Biochemistry, 43, 2004
1UU0	Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima (Apo-form) Descriptor: HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PHOSPHATE ION Authors: Vega, M.C, Fernandez, F.J, Lehmann, F, Wilmanns, M. Deposit date: 2003-12-12 Release date: 2004-05-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
1UU2	Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima (apo-form) Descriptor: 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, HISTIDINOL-PHOSPHATE AMINOTRANSFERASE Authors: Vega, M.C, Fernandez, F.J, Lehmann, F, Wilmanns, M. Deposit date: 2003-12-13 Release date: 2004-03-18 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
1TAR	CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE Authors: Hohenester, E, Jansonius, J.N. Deposit date: 1993-10-04 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystalline mitochondrial aspartate aminotransferase exists in only two conformations. J.Mol.Biol., 236, 1994
1V2E	Crystal Structure of T.th HB8 Glutamine Aminotransferase complex with a-keto-g-methylthiobutyrate Descriptor: 4-(METHYLSULFANYL)-2-OXOBUTANOIC ACID, Glutamine Aminotransferase, PYRIDOXAL-5'-PHOSPHATE Authors: Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2003-10-15 Release date: 2004-07-06 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition J.BIOL.CHEM., 279, 2004
1UU1	Complex of Histidinol-phosphate aminotransferase (HisC) from Thermotoga maritima (Apo-form) Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER Authors: Vega, M.C, Fernandez, F.J, Lehman, F, Wilmanns, M. Deposit date: 2003-12-12 Release date: 2004-03-18 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Structural Studies of the Catalytic Reaction Pathway of a Hyperthermophilic Histidinol-Phosphate Aminotransferase J.Biol.Chem., 279, 2004
1U08	Crystal Structure and Reactivity of YbdL from Escherichia coli Identify a Methionine Aminotransferase Function. Descriptor: Hypothetical aminotransferase ybdL, PYRIDOXAL-5'-PHOSPHATE Authors: Dolzan, M, Johansson, K, Roig-Zamboni, V, Campanacci, V, Tegoni, M, Schneider, G, Cambillau, C. Deposit date: 2004-07-13 Release date: 2004-07-27 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure and reactivity of YbdL from Escherichia coli identify a methionine aminotransferase function FEBS Lett., 571, 2004
1W7L	Crystal structure of human kynurenine aminotransferase I Descriptor: KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PYRIDOXAL-5'-PHOSPHATE Authors: Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. Deposit date: 2004-09-06 Release date: 2004-09-08 Last modified: 2015-12-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
4EFF	Crystal structure of aromatic-amino-acid aminotransferase from Burkholderia pseudomallei Descriptor: Aromatic-amino-acid aminotransferase, GLYCEROL Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-03-29 Release date: 2012-04-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of aromatic-amino-acid aminotransferase from Burkholderia pseudomallei To be Published
4EU1	Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Mitochondrial aspartate aminotransferase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-25 Release date: 2012-05-16 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015
4F5J	Rational Design and Directed Evolution for Conversion of Substrate Specificity from E.coli Aspartate Aminotransferase to Tyrosine Aminotransferase: Mutant P5. Descriptor: Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-02-13 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.954 Å) Cite: Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5F	Structure of Aspartate Aminotransferase Conversion to Tyrosine Aminotransferase: Chimera P1. Descriptor: Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-02-13 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5M	Wild-Type E. coli Aspartate Aminotransferase: A Template For The Interconversion of Substrate Specificity and Activity To Tyrosine Aminotransferase By The JANUS Algorithm. Descriptor: 1,2-ETHANEDIOL, Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-02-13 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5I	Substrate Specificity Conversion of E. coli Pyridoxal-5'-Phosphate Dependent Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P4. Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-02-13 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5H	Intercoversion of Substrate Specificity: E. coli Aspatate Aminotransferase to Tyrosine Aminotransferase: Chimera P3. Descriptor: Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-02-13 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4F5G	Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2. Descriptor: Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-02-13 Last modified: 2013-04-24 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425, 2013
4GEB	Kynurenine Aminotransferase II Inhibitors Descriptor: (5-hydroxy-4-{[(7-hydroxy-6-oxo-2-phenyl-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-5-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, ... Authors: Pandit, J. Deposit date: 2012-08-01 Release date: 2013-03-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: PF-04859989 as a template for structure-based drug design: identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency. Bioorg.Med.Chem.Lett., 23, 2013
4GE7	Kynurenine Aminotransferase II Inhibitors Descriptor: (5-hydroxy-4-{[(1-hydroxy-2-oxo-6-phenoxy-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Authors: Pandit, J. Deposit date: 2012-08-01 Release date: 2012-11-07 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013
4GE4	Kynurenine Aminotransferase II Inhibitors Descriptor: (5-hydroxy-4-{[(1-hydroxy-7-methoxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Authors: Pandit, J. Deposit date: 2012-08-01 Release date: 2012-11-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions. ACS Med Chem Lett, 4, 2013
4H51	Crystal structure of a putative Aspartate Aminotransferase from Leishmania major Friedlin Descriptor: 1,2-ETHANEDIOL, Aspartate aminotransferase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-09-18 Release date: 2012-10-10 Last modified: 2015-05-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015
4F5L	A Theoretical Optimized Mutant for the Conversion of Substrate Specificity and Activity of Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P7. Descriptor: 1,2-ETHANEDIOL, Aspartate aminotransferase Authors: Addington, T.A, Fisher, A.J, Toney, M.D. Deposit date: 2012-05-13 Release date: 2013-05-15 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Janus: an algorithm for ranking functional importance of residues from protein sequence alignments. To be Published
4FL0	Crystal structure of ALD1 from Arabidopsis thaliana Descriptor: Aminotransferase ALD1, PYRIDOXAL-5'-PHOSPHATE Authors: Sobolev, V, Edelman, M, Dym, O, Unger, T, Albeck, S, Kirma, M, Galili, G, Israel Structural Proteomics Center (ISPC) Deposit date: 2012-06-14 Release date: 2013-02-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis. Acta Crystallogr.,Sect.F, 69, 2013

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