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1O4Q	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU79256. Descriptor: PHENYL(SULFO)ACETIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1NRV	Crystal structure of the SH2 domain of Grb10 Descriptor: Growth factor receptor-bound protein 10 Authors: Stein, E.G, Hubbard, S.R. Deposit date: 2003-01-25 Release date: 2003-04-15 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity. J.Biol.Chem., 278, 2003
1O4N	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH OXALIC ACID. Descriptor: OXALIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1NZV	Crystal Structure of Src SH2 domain bound to doubly phosphorylated peptide PQpYIpYVPA Descriptor: CHLORIDE ION, Doubly phosphorylated peptide PQpYIpYVPA, TETRAETHYLENE GLYCOL, ... Authors: Lubman, O.Y, Waksman, G. Deposit date: 2003-02-19 Release date: 2003-04-22 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural and Thermodynamic Basis for the Interaction of the Src SH2 domain with the Activated form of the PDGF beta-receptor J.Mol.Biol., 328, 2003
1O4D	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78262. Descriptor: 2-FORMYLPHENYL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O45	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU84687. Descriptor: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-3-FORMYL-O-PHOSPHONOTYROSINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4F	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU79073. Descriptor: 1,2,3,4-TETRAHYDROQUINOLIN-8-YL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4J	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH ISO24. Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, [(4-ETHYLPHENYL)AMINO]CARBONYLPHOSPHONIC ACID Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4K	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH PASBN. Descriptor: BENZYL 2-FORMYLPHENYL HYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O43	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82129. Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, [4-((1Z)-2-(ACETYLAMINO)-3-{[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]AMINO}-3-OXOPROP-1-ENYL)-2-FORMYLPHENYL]ACET IC ACID Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O49	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU85493. Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, {4-[2-ACETYLAMINO-2-(1-BIPHENYL-4-YLMETHYL-2-OXO-AZEPAN-3-YLCARBAMOYL)-ETHYL]-2-PHOSPHONO-PHENOXY}-ACETIC ACID Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4G	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH DPI59. Descriptor: HYDROXY(1-NAPHTHYL)METHYLPHOSPHONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4M	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH MALONICACID. Descriptor: MALONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4A	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82197. Descriptor: 4-[2-ACETYLAMINO-2-(1-BIPHENYL-4-YLMETHYL-2-OXO-AZEPAN-3-YLCARBAMOYL)-ETHYL]-2-FORMYL-BENZOIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC Authors: Lange, G, Loenze, P, Liesum, A. Deposit date: 2003-06-15 Release date: 2004-02-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
8X2P	The Crystal Structure of LCK from Biortus. Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, TETRAETHYLENE GLYCOL, ... Authors: Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. Deposit date: 2023-11-10 Release date: 2023-11-22 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The Crystal Structure of LCK from Biortus. To Be Published
1A1A	C-SRC (SH2 DOMAIN WITH C188A MUTATION) COMPLEXED WITH ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) Descriptor: ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-10 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A08	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-DIFLUORO PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) Descriptor: ACE-DIFLUORO PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-09 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A09	C-src (SH2 domain) complexed with ace-formyl phosphotyr-glu-(n,n-dipentyl amine) Descriptor: ACE-FORMYL PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-10 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A1E	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE) Descriptor: ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-10 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A1B	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) Descriptor: ACE-PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-10 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A1C	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL)) Descriptor: ACE-PHOSPHOTYR-GLU-(N-ME(-(CH2)3-CYCLOPENTYL)), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-10 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1A07	C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE) Descriptor: ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE), C-SRC TYROSINE KINASE Authors: Shewchuk, L, Jordan, S. Deposit date: 1997-12-09 Release date: 1998-04-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36, 1997
1AB2	THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL Descriptor: C-ABL TYROSINE KINASE SH2 DOMAIN Authors: Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. Deposit date: 1993-07-19 Release date: 1994-01-31 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Three-dimensional solution structure of the src homology 2 domain of c-abl. Cell(Cambridge,Mass.), 70, 1992
1AYB	CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE Descriptor: PEPTIDE IRS-1-895, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) Authors: Lee, C.-H, Kuriyan, J. Deposit date: 1994-05-15 Release date: 1994-08-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure, 2, 1994
1AYD	CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE Descriptor: PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) Authors: Lee, C.-H, Kuriyan, J. Deposit date: 1994-05-15 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. Structure, 2, 1994

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