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2J0Q
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The crystal structure of the Exon Junction Complex at 3.2 A resolution
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ...
Authors:Bono, F, Ebert, J, Lorentzen, E, Conti, E.
Deposit date:2006-08-04
Release date:2006-08-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
5A7R
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BU of 5a7r by Molmil
Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose
Descriptor: BETA-MERCAPTOETHANOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
Authors:Lambrecht, M.J, Brichacek, M, Barkauskaite, E, Ariza, A, Ahel, I, Hergenrother, P.J.
Deposit date:2015-07-09
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Synthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase.
J.Am.Chem.Soc., 137, 2015
2VP4
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Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE KINASE
Authors:Mikkelsen, N.E, Munch-Petersen, B, Eklund, H.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase.
FEBS J., 275, 2008
1PGS
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BU of 1pgs by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF PNGASE F, A GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM
Descriptor: PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F
Authors:Norris, G.E, Stillman, T.J, Anderson, B.F, Baker, E.N.
Deposit date:1994-10-06
Release date:1995-01-26
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The three-dimensional structure of PNGase F, a glycosylasparaginase from Flavobacterium meningosepticum.
Structure, 2, 1994
8SVN
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BU of 8svn by Molmil
Crystal structure of the apo form of pregnane X receptor ligand binding domain
Descriptor: Pregnane X receptor ligand binding domain fused to SRC-1 coactivator peptide
Authors:Garcia-Maldonado, E, Huber, A.D, Nithianantham, S, Miller, D.J, Chen, T.
Deposit date:2023-05-17
Release date:2024-05-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chemical manipulation of an activation/inhibition switch in the nuclear receptor PXR.
Nat Commun, 15, 2024
7KTS
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BU of 7kts by Molmil
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
Descriptor: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ...
Authors:Herbst, D.A, Esbin, M.N, Nogales, E.
Deposit date:2020-11-24
Release date:2021-11-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (19.09 Å)
Cite:Structure of the human SAGA coactivator complex.
Nat.Struct.Mol.Biol., 28, 2021
1E47
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BU of 1e47 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73Q
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of l-fuculose-1-phosphate aldolase mutants outlining motions during catalysis.
J. Mol. Biol., 303, 2000
1E4C
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BU of 1e4c by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant S71Q
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1KDQ
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BU of 1kdq by Molmil
Crystal Structure Analysis of the Mutant S189D Rat Chymotrypsin
Descriptor: CALCIUM ION, CHYMOTRYPSIN B, B CHAIN, ...
Authors:Szabo, E, Bocskei, Z, Naray-Szabo, G, Graf, L, Venekei, I.
Deposit date:2001-11-13
Release date:2003-06-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Three Dimensional Structures of S189D Chymotrypsin and D189S Trypsin Mutants: The Effect of Polarity at Site 189 on a Protease-specific Stabilization of the Substrate-binding Site
J.Mol.Biol., 331, 2003
3NBR
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BU of 3nbr by Molmil
Crystal Structure of Ketosteroid Isomerase D38NP39GD99N from Pseudomonas Testosteroni (tKSI) with 4-Androstene-3,17-dione Bound
Descriptor: 4-ANDROSTENE-3-17-DIONE, SULFATE ION, Steroid Delta-isomerase
Authors:Gonzalez, A, Tsai, Y, Schwans, J, Ruben, E, Sunden, F, Herschlag, D.
Deposit date:2010-06-03
Release date:2011-11-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal Structure of Ketosteroid Isomerase D38NP39GD99N from Pseudomonas Testosteroni (tKSI) with 4-Androstene-3,17-dione Bound
To be Published
1YUP
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BU of 1yup by Molmil
Reindeer beta-lactoglobulin
Descriptor: beta-lactoglobulin
Authors:Goldman, A, Oksanen, E.
Deposit date:2005-02-14
Release date:2006-02-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Reindeer beta-lactoglobulin crystal structure with pseudo-body-centred noncrystallographic symmetry.
Acta Crystallogr.,Sect.D, 62, 2006
4BC4
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BU of 4bc4 by Molmil
Crystal structure of human D-xylulokinase in complex with D-xylulose
Descriptor: 1,2-ETHANEDIOL, D-XYLULOSE, XYLULOSE KINASE
Authors:Bunker, R.D, Loomes, K.M, Baker, E.N.
Deposit date:2012-10-01
Release date:2012-11-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
J.Biol.Chem., 288, 2013
1KEC
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BU of 1kec by Molmil
PENICILLIN ACYLASE MUTANT WITH PHENYL PROPRIONIC ACID
Descriptor: CALCIUM ION, PENICILLIN ACYLASE ALPHA SUBUNIT, PENICILLIN ACYLASE BETA SUBUNIT, ...
Authors:Hensgens, C.M.H, Keizer, E, Snijder, H.J, Dijkstra, B.W.
Deposit date:2001-11-15
Release date:2003-09-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase.
Protein Eng.Des.Sel., 17, 2004
4BDU
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BU of 4bdu by Molmil
Bax BH3-in-Groove dimer (GFP)
Descriptor: GREEN FLUORESCENT PROTEIN, APOPTOSIS REGULATOR BAX
Authors:Czabotar, P.E, Colman, P.M.
Deposit date:2012-10-08
Release date:2013-02-13
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.998 Å)
Cite:Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
4BA1
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BU of 4ba1 by Molmil
Archaeal exosome (Rrp4-Rrp41(D182A)-Rrp42) bound to inorganic phosphate
Descriptor: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PHOSPHATE ION, ...
Authors:Lorentzen, E, Conti, E.
Deposit date:2012-09-10
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a 9-Subunit Archaeal Exosome in Pre-Catalytic States of the Phosphorolytic Reaction.
Archaea, 2012, 2012
7KR2
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BU of 7kr2 by Molmil
ClpP from Neisseria meningitidis - Compressed conformation
Descriptor: ATP-dependent Clp protease proteolytic subunit
Authors:Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
Deposit date:2020-11-18
Release date:2021-11-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A pH-Dependent Conformational Switch Controls N. meningitidis ClpP Protease Function
To Be Published
5AJA
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BU of 5aja by Molmil
Crystal structure of mandrill SAMHD1 (amino acid residues 1-114) bound to Vpx isolated from mandrill and human DCAF1 (amino acid residues 1058-1396)
Descriptor: PROTEIN VPRBP, SAM DOMAIN AND HD DOMAIN-CONTAINING PROTEIN, VPX PROTEIN, ...
Authors:Schwefel, D, Boucherit, V.C, Christodoulou, E, Walker, P.A, Stoye, J.P, Bishop, K.N, Taylor, I.A.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.649 Å)
Cite:Molecular Determinants for Recognition of Divergent Samhd1 Proteins by the Lentiviral Accessory Protein Vpx.
Cell Host Microbe., 17, 2015
5AFA
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BU of 5afa by Molmil
Crystal structure of Laccase from Thermus thermophilus HB27 complexed with Ag, crystal of the holoenzyme soaked for 30 m in 5 mM AgNO3 at 278 K.
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, ...
Authors:Jimenez-Arroyo, N, Rudino-Pinera, E.
Deposit date:2015-01-19
Release date:2016-02-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Structural Function of the Methionine-Rich Beta-Hairpin in the Laccase for T. Thermophilus.
To be Published
4J9U
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BU of 4j9u by Molmil
Crystal Structure of the TrkH/TrkA potassium transport complex
Descriptor: HEXATANTALUM DODECABROMIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ...
Authors:Cao, Y, Jin, X, Huang, H, Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2013-02-17
Release date:2013-04-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Gating of the TrkH ion channel by its associated RCK protein TrkA.
Nature, 496, 2013
2V6B
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BU of 2v6b by Molmil
Crystal structure of lactate dehydrogenase from Deinococcus Radiodurans (apo form)
Descriptor: L-LACTATE DEHYDROGENASE
Authors:Coquelle, N, Fioravanti, E, Weik, M, Vellieux, F.
Deposit date:2007-07-16
Release date:2007-09-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments.
J. Mol. Biol., 374, 2007
2V7G
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BU of 2v7g by Molmil
Crystal Structure of an Engineered Urocanase Tetramer
Descriptor: ACETATE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Treiber, N, Schulz, G.E.
Deposit date:2007-07-30
Release date:2008-01-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Designed Protein-Protein Association.
Science, 319, 2008
2OGE
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BU of 2oge by Molmil
x-ray structure of S. venezuelae DesV in its internal aldimine form
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
Authors:Holden, H.M, Burgie, E.S.
Deposit date:2007-01-05
Release date:2007-05-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine.
Protein Sci., 16, 2007
3V5T
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BU of 3v5t by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1299
Descriptor: 1-[(2S)-2-(dimethylamino)-3-methylbutyl]-3-(6-ethoxynaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A, Larson, E.T.
Deposit date:2011-12-16
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1.
J.Med.Chem., 55, 2012
2ICX
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BU of 2icx by Molmil
Crystal Structure of a Putative UDP-glucose Pyrophosphorylase from Arabidopsis Thaliana with Bound UTP
Descriptor: DIMETHYL SULFOXIDE, Probable UTP-glucose-1-phosphate uridylyltransferase 2, URIDINE 5'-TRIPHOSPHATE
Authors:McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-09-13
Release date:2006-09-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure and Dynamics of UDP-Glucose Pyrophosphorylase from Arabidopsis thaliana with Bound UDP-Glucose and UTP.
J.Mol.Biol., 366, 2007
7KQF
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BU of 7kqf by Molmil
The internal aldimine form of the wild-type Tryptophan Synthase from Salmonella in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.47 Angstrom resolution
Descriptor: 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ...
Authors:Hilario, E, Dunn, M.F, Mueller, L.J.
Deposit date:2020-11-15
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The internal aldimine form of the wild-type Tryptophan Synthase from Salmonella in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.47 Angstrom resolution.
To be Published

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