5XJC
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![BU of 5xjc by Molmil](/molmil-images/mine/5xjc) | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | Deposit date: | 2017-04-30 | Release date: | 2017-07-05 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
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6TED
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![BU of 6ted by Molmil](/molmil-images/mine/6ted) | Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 | Descriptor: | DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ... | Authors: | Vos, S.M, Farnung, L, Cramer, P. | Deposit date: | 2019-11-11 | Release date: | 2020-07-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation. Nat.Struct.Mol.Biol., 27, 2020
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3H0G
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![BU of 3h0g by Molmil](/molmil-images/mine/3h0g) | RNA Polymerase II from Schizosaccharomyces pombe | Descriptor: | DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2009-04-09 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution. Proc.Natl.Acad.Sci.USA, 106, 2009
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5XON
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![BU of 5xon by Molmil](/molmil-images/mine/5xon) | RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS | Descriptor: | DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. | Deposit date: | 2017-05-29 | Release date: | 2017-08-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
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6TQO
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![BU of 6tqo by Molmil](/molmil-images/mine/6tqo) | rrn anti-termination complex | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6TQN
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![BU of 6tqn by Molmil](/molmil-images/mine/6tqn) | rrn anti-termination complex without S4 | Descriptor: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6VZ3
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![BU of 6vz3 by Molmil](/molmil-images/mine/6vz3) | Escherichia coli transcription-translation complex D2 (TTC-D2) containing mRNA with a 27 nt long spacer | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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5X4Z
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![BU of 5x4z by Molmil](/molmil-images/mine/5x4z) | RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | Deposit date: | 2017-02-14 | Release date: | 2017-05-17 | Method: | X-RAY DIFFRACTION (7.8 Å) | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
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5X8R
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![BU of 5x8r by Molmil](/molmil-images/mine/5x8r) | Structure of the 30S small subunit of chloroplast ribosome from spinach | Descriptor: | 16S rRNA, 30S ribosomal protein S1, chloroplastic, ... | Authors: | Ahmed, T, Shi, J, Bhushan, S. | Deposit date: | 2017-03-03 | Release date: | 2017-06-07 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation Nucleic Acids Res., 45, 2017
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6VZ5
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![BU of 6vz5 by Molmil](/molmil-images/mine/6vz5) | Escherichia coli transcription-translation complex D3 (TTC-D3) containing mRNA with a 21 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6VU3
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![BU of 6vu3 by Molmil](/molmil-images/mine/6vu3) | Cryo-EM structure of Escherichia coli transcription-translation complex A (TTC-A) containing mRNA with a 12 nt long spacer | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R. | Deposit date: | 2020-02-14 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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5X8P
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![BU of 5x8p by Molmil](/molmil-images/mine/5x8p) | Structure of the 70S chloroplast ribosome from spinach | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Ahmed, T, Shi, J, Bhushan, S. | Deposit date: | 2017-03-03 | Release date: | 2017-06-14 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation Nucleic Acids Res., 45, 2017
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6VZJ
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![BU of 6vzj by Molmil](/molmil-images/mine/6vzj) | Escherichia coli transcription-translation complex A1 (TTC-A1) containing mRNA with a 15 nt long spacer, fMet-tRNAs at E-site and P-site, and lacking transcription factor NusG | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-28 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6VYZ
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![BU of 6vyz by Molmil](/molmil-images/mine/6vyz) | Escherichia coli transcription-translation complex C6 (TTC-C6) containing mRNA with a 21 nt long spacer, NusA, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (9.9 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6VYR
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![BU of 6vyr by Molmil](/molmil-images/mine/6vyr) | Escherichia coli transcription-translation complex A1 (TTC-A1) containing an 18 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6VYT
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![BU of 6vyt by Molmil](/molmil-images/mine/6vyt) | Escherichia coli transcription-translation complex A2 (TTC-A2) containing a 15 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Ebright, R.H, Su, M. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6VZ2
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![BU of 6vz2 by Molmil](/molmil-images/mine/6vz2) | Escherichia coli transcription-translation complex D1 (TTC-D1) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6VYU
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![BU of 6vyu by Molmil](/molmil-images/mine/6vyu) | Escherichia coli transcription-translation complex C2 (TTC-C2) containing a 27 nt long mRNA spacer | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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3H3V
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![BU of 3h3v by Molmil](/molmil-images/mine/3h3v) | Yeast RNAP II containing poly(A)-signal sequence in the active site | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*GP*CP*TP*GP*CP*TP*TP*TP*AP*TP*TP*GP*CP*AP*TP*T)-3', 5'-D(*CP*AP*GP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*CP*AP*AP*UP*AP*AP*A)-3', ... | Authors: | Dengl, S, Cramer, P. | Deposit date: | 2009-04-17 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Torpedo Nuclease Rat1 Is Insufficient to Terminate RNA Polymerase II in Vitro J.Biol.Chem., 284, 2009
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5XOG
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![BU of 5xog by Molmil](/molmil-images/mine/5xog) | RNA Polymerase II elongation complex bound with Spt5 KOW5 and Elf1 | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (30-MER), DNA (39-MER), ... | Authors: | Ehara, H, Shirouzu, M, Sekine, S. | Deposit date: | 2017-05-28 | Release date: | 2017-08-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
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3HOV
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![BU of 3hov by Molmil](/molmil-images/mine/3hov) | Complete RNA polymerase II elongation complex II | Descriptor: | 5'-D(*AP*GP*CP*TP*CP*AP*A*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*T*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', ... | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | Deposit date: | 2009-06-03 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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3HOW
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![BU of 3how by Molmil](/molmil-images/mine/3how) | Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine | Descriptor: | 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ... | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | Deposit date: | 2009-06-03 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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3HKZ
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![BU of 3hkz by Molmil](/molmil-images/mine/3hkz) | The X-ray crystal structure of RNA polymerase from Archaea | Descriptor: | DNA-directed RNA polymerase subunit 13, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | Authors: | Murakami, K.S. | Deposit date: | 2009-05-26 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The X-ray crystal structure of RNA polymerase from Archaea. Nature, 451, 2008
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3I4M
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![BU of 3i4m by Molmil](/molmil-images/mine/3i4m) | 8-oxoguanine containing RNA polymerase II elongation complex D | Descriptor: | DNA (5'-D(*AP*G*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*(8OG)P*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | Authors: | Damsma, G.E, Cramer, P. | Deposit date: | 2009-07-02 | Release date: | 2009-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Molecular basis of transcriptional mutagenesis at 8-oxoguanine J.Biol.Chem., 284, 2009
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3HOY
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![BU of 3hoy by Molmil](/molmil-images/mine/3hoy) | Complete RNA polymerase II elongation complex VI | Descriptor: | 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ... | Authors: | Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P. | Deposit date: | 2009-06-03 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Mol.Cell, 34, 2009
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