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3RMB
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BU of 3rmb by Molmil
Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol
Descriptor: DNA (5'-D(*CP*GP*CP*(CTG)P*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*CP*A)-3'), DNA polymerase, ...
Authors:Aller, P, Duclos, S, Wallace, S.S, Doublie, S.
Deposit date:2011-04-20
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex.
J.Mol.Biol., 412, 2011
3RMD
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BU of 3rmd by Molmil
Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*(CTG)P*G*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*CP*AP*A)-3'), ...
Authors:Aller, P, Duclos, S, Wallace, S.S, Doublie, S.
Deposit date:2011-04-20
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A crystallographic study of the role of sequence context in thymine glycol bypass by a replicative DNA polymerase serendipitously sheds light on the exonuclease complex.
J.Mol.Biol., 412, 2011
3RWU
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BU of 3rwu by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Difluorotoluene Nucleoside
Descriptor: 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*GP*(DFT)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Xia, S, Konigsberg, W.H, Wang, J.
Deposit date:2011-05-09
Release date:2011-06-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Hydrogen-Bonding Capability of a Templating Difluorotoluene Nucleotide Residue in an RB69 DNA Polymerase Ternary Complex.
J.Am.Chem.Soc., 133, 2011
3KD5
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BU of 3kd5 by Molmil
Closed ternary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair and phosphonoformic acid.
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2009-10-22
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase.
J.Biol.Chem., 286, 2011
3KD1
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BU of 3kd1 by Molmil
Closed binary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair.
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2009-10-22
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase.
J.Biol.Chem., 286, 2011
3NCI
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BU of 3nci by Molmil
RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J.
Deposit date:2010-06-04
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex.
Biochemistry, 50, 2011
3NHG
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BU of 3nhg by Molmil
RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dTTP Opposite dG
Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-14
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NDK
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BU of 3ndk by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dCTP Opposite dG
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-07
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NE6
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BU of 3ne6 by Molmil
RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dCTP Opposite dG
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-08
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NGI
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BU of 3ngi by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite dG
Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-11
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.886 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NAE
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BU of 3nae by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-01
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Biochemistry, 49, 2010
2XHB
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BU of 2xhb by Molmil
Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA
Descriptor: 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, ...
Authors:Killelea, T, Ghosh, S, Tan, S.S, Heslop, P, Firbank, S.J, Kool, E.T, Connolly, B.A.
Deposit date:2010-06-14
Release date:2010-07-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues.
Biochemistry, 49, 2010
3LDS
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BU of 3lds by Molmil
Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*(8OG)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(DDG))-3'), ...
Authors:Hogg, M, Midkiff, J, Rudnicki, J, Reha-Krantz, L, Doublie, S, Wallace, S.S.
Deposit date:2010-01-13
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69.
Biochemistry, 49, 2010
3LZJ
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BU of 3lzj by Molmil
RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine
Descriptor: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
Deposit date:2010-03-01
Release date:2010-05-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3LZI
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BU of 3lzi by Molmil
RB69 DNA Polymerase (Y567A) ternary complex with dATP Opposite 7,8-dihydro-8-oxoguanine
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
Deposit date:2010-03-01
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3MAQ
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BU of 3maq by Molmil
Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2010-03-24
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3L8B
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BU of 3l8b by Molmil
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin
Descriptor: DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), DNA polymerase, ...
Authors:Aller, P, Ye, Y, Wallace, S.S, Burrows, C.J, Doublie, S.
Deposit date:2009-12-30
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.
Biochemistry, 49, 2010
3K59
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BU of 3k59 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K58
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BU of 3k58 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex
Descriptor: DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K57
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BU of 3k57 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K5O
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BU of 3k5o by Molmil
Crystal structure of E.coli Pol II
Descriptor: DNA polymerase II
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K5N
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BU of 3k5n by Molmil
Crystal structure of E.coli Pol II-abasic DNA binary complex
Descriptor: DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K5M
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BU of 3k5m by Molmil
Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K5L
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BU of 3k5l by Molmil
Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3A2F
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BU of 3a2f by Molmil
Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex
Descriptor: DNA polymerase, DNA polymerase sliding clamp
Authors:Nishida, H, Ishino, Y, Morikawa, K.
Deposit date:2009-05-15
Release date:2009-11-03
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex
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