6R7Q
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![BU of 6r7q by Molmil](/molmil-images/mine/6r7q) | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | Deposit date: | 2019-03-29 | Release date: | 2019-07-10 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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5A6U
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![BU of 5a6u by Molmil](/molmil-images/mine/5a6u) | Native mammalian ribosome-bound Sec61 protein-conducting channel in the 'non-inserting' state | Descriptor: | SEC61A, SEC61B, SEC61G | Authors: | Pfeffer, S, Burbaum, L, Unverdorben, P, Pech, M, Chen, Y, Zimmermann, R, Beckmann, R, Foerster, F. | Deposit date: | 2015-07-01 | Release date: | 2015-10-07 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structure of the Native Sec61 Protein-Conducting Channel. Nat.Commun., 6, 2015
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6W6L
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![BU of 6w6l by Molmil](/molmil-images/mine/6w6l) | |
7AFT
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![BU of 7aft by Molmil](/molmil-images/mine/7aft) | Cryo-EM structure of the signal sequence-engaged post-translational Sec translocon | Descriptor: | Mating factor alpha-1,Mating factor alpha-1, Protein translocation protein SEC63, Protein transport protein SBH1, ... | Authors: | Weng, T.-H, Beatrix, B, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | Deposit date: | 2020-09-20 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Architecture of the active post-translational Sec translocon. Embo J., 40, 2021
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3DKN
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![BU of 3dkn by Molmil](/molmil-images/mine/3dkn) | |
4V4N
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![BU of 4v4n by Molmil](/molmil-images/mine/4v4n) | Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein L7AE, ... | Authors: | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | Deposit date: | 2013-06-17 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
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4V7I
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![BU of 4v7i by Molmil](/molmil-images/mine/4v7i) | Ribosome-SecY complex. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gumbart, J.C, Trabuco, L.G, Schreiner, E, Villa, E, Schulten, K. | Deposit date: | 2009-10-21 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (9.6 Å) | Cite: | Regulation of the protein-conducting channel by a bound ribosome. Structure, 17, 2009
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6N3Q
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![BU of 6n3q by Molmil](/molmil-images/mine/6n3q) | Cryo-EM structure of the yeast Sec complex | Descriptor: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | Authors: | Park, E, Itskanov, S. | Deposit date: | 2018-11-16 | Release date: | 2018-12-19 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structure of the posttranslational Sec protein-translocation channel complex from yeast. Science, 363, 2019
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8OJ8
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![BU of 8oj8 by Molmil](/molmil-images/mine/8oj8) | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | Deposit date: | 2023-03-24 | Release date: | 2024-02-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
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8B6L
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![BU of 8b6l by Molmil](/molmil-images/mine/8b6l) | Subtomogram average of the human Sec61-TRAP-OSTA-translocon | Descriptor: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... | Authors: | Gemmer, M, Fedry, J.M.M, Forster, F.G. | Deposit date: | 2022-09-27 | Release date: | 2022-12-07 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Visualization of translation and protein biogenesis at the ER membrane. Nature, 614, 2023
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1RH5
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![BU of 1rh5 by Molmil](/molmil-images/mine/1rh5) | The structure of a protein conducting channel | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | Deposit date: | 2003-11-13 | Release date: | 2004-01-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | X-ray structure of a protein-conducting channel Nature, 427, 2004
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7TM3
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![BU of 7tm3 by Molmil](/molmil-images/mine/7tm3) | Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-01-19 | Release date: | 2022-10-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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7TUT
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![BU of 7tut by Molmil](/molmil-images/mine/7tut) | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-02-03 | Release date: | 2022-10-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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6ND1
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![BU of 6nd1 by Molmil](/molmil-images/mine/6nd1) | CryoEM structure of the Sec Complex from yeast | Descriptor: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | Authors: | Wu, X, Cabanos, C, Rapoport, T.A. | Deposit date: | 2018-12-13 | Release date: | 2019-01-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of the post-translational protein translocation machinery of the ER membrane. Nature, 566, 2019
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8OJ0
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![BU of 8oj0 by Molmil](/molmil-images/mine/8oj0) | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | Deposit date: | 2023-03-23 | Release date: | 2024-02-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
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1RHZ
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![BU of 1rhz by Molmil](/molmil-images/mine/1rhz) | The structure of a protein conducting channel | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | Deposit date: | 2003-11-15 | Release date: | 2004-01-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | X-ray structure of a protein-conducting channel. Nature, 427, 2004
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8BTK
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![BU of 8btk by Molmil](/molmil-images/mine/8btk) | Structure of the TRAP complex with the Sec translocon and a translating ribosome | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | Authors: | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | Deposit date: | 2022-11-29 | Release date: | 2023-05-24 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis of the TRAP complex function in ER protein biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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2WWA
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![BU of 2wwa by Molmil](/molmil-images/mine/2wwa) | Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | Deposit date: | 2009-10-22 | Release date: | 2009-12-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
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8RJB
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2WW9
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![BU of 2ww9 by Molmil](/molmil-images/mine/2ww9) | Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | Deposit date: | 2009-10-22 | Release date: | 2009-12-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.6 Å) | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
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4CG5
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![BU of 4cg5 by Molmil](/molmil-images/mine/4cg5) | Cryo-EM of the Sec61-complex bound to the 80S ribosome translating a secretory substrate | Descriptor: | PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA | Authors: | Gogala, M, Becker, T, Beatrix, B, Barrio-Garcia, C, Berninghausen, O, Beckmann, R. | Deposit date: | 2013-11-21 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion. Nature, 506, 2014
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6FTI
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![BU of 6fti by Molmil](/molmil-images/mine/6fti) | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Braunger, K, Becker, T, Beckmann, R. | Deposit date: | 2018-02-22 | Release date: | 2018-03-21 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
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2WWB
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![BU of 2wwb by Molmil](/molmil-images/mine/2wwb) | CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME | Descriptor: | 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | Deposit date: | 2009-10-22 | Release date: | 2009-12-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.48 Å) | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
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8RJC
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8RJD
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![BU of 8rjd by Molmil](/molmil-images/mine/8rjd) | |