7KC0
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![BU of 7kc0 by Molmil](/molmil-images/mine/7kc0) | Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... | Authors: | Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. | Deposit date: | 2020-10-04 | Release date: | 2020-12-02 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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7KQ1
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![BU of 7kq1 by Molmil](/molmil-images/mine/7kq1) | PCNA bound to truncated peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2020-11-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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7KQ0
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![BU of 7kq0 by Molmil](/molmil-images/mine/7kq0) | PCNA bound to peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2020-11-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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5V7L
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![BU of 5v7l by Molmil](/molmil-images/mine/5v7l) | |
5IY4
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![BU of 5iy4 by Molmil](/molmil-images/mine/5iy4) | |
1ISQ
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![BU of 1isq by Molmil](/molmil-images/mine/1isq) | Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide | Descriptor: | Proliferating Cell Nuclear Antigen, replication factor C large subunit | Authors: | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | Deposit date: | 2001-12-19 | Release date: | 2002-10-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Physical interaction between proliferating cell nuclear antigen and
replication factor C from Pyrococcus furiosus Genes Cells, 7, 2002
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1IZ5
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![BU of 1iz5 by Molmil](/molmil-images/mine/1iz5) | Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form | Descriptor: | Proliferating cell nuclear antigen | Authors: | Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. | Deposit date: | 2002-09-23 | Release date: | 2003-04-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA PROTEIN SCI., 12, 2003
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5MLW
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![BU of 5mlw by Molmil](/molmil-images/mine/5mlw) | |
5MLO
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![BU of 5mlo by Molmil](/molmil-images/mine/5mlo) | |
5MAV
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![BU of 5mav by Molmil](/molmil-images/mine/5mav) | |
4YHR
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![BU of 4yhr by Molmil](/molmil-images/mine/4yhr) | Crystal Structure of Yeast Proliferating Cell Nuclear Antigen | Descriptor: | Proliferating cell nuclear antigen | Authors: | Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T. | Deposit date: | 2015-02-27 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.9502 Å) | Cite: | Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures To be published
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5MOM
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![BU of 5mom by Molmil](/molmil-images/mine/5mom) | |
4ZTD
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![BU of 4ztd by Molmil](/molmil-images/mine/4ztd) | Crystal Structure of Human PCNA in complex with a TRAIP peptide | Descriptor: | ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen | Authors: | Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. | Deposit date: | 2015-05-14 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
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5A6D
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![BU of 5a6d by Molmil](/molmil-images/mine/5a6d) | Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans | Descriptor: | DNA POLYMERASE SLIDING CLAMP | Authors: | Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E. | Deposit date: | 2015-06-25 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans. Biochem Biophys Rep, 8, 2016
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5AUJ
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![BU of 5auj by Molmil](/molmil-images/mine/5auj) | |
3V62
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![BU of 3v62 by Molmil](/molmil-images/mine/3v62) | Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 | Descriptor: | ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... | Authors: | Armstrong, A.A, Mohideen, F, Lima, C.D. | Deposit date: | 2011-12-18 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
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6EHT
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![BU of 6eht by Molmil](/molmil-images/mine/6eht) | Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme | Descriptor: | DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ... | Authors: | De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. | Deposit date: | 2017-09-15 | Release date: | 2018-08-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | p15PAF binding to PCNA modulates the DNA sliding surface. Nucleic Acids Res., 46, 2018
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3LX2
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![BU of 3lx2 by Molmil](/molmil-images/mine/3lx2) | |
6FCM
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![BU of 6fcm by Molmil](/molmil-images/mine/6fcm) | Crystal structure of human PCNA | Descriptor: | Proliferating cell nuclear antigen | Authors: | Housset, D, Frachet, P. | Deposit date: | 2017-12-20 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
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7QNZ
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![BU of 7qnz by Molmil](/molmil-images/mine/7qnz) | human Lig1-DNA-PCNA complex reconstituted in absence of ATP | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA ligase 1, Oligo13P, ... | Authors: | Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. | Deposit date: | 2021-12-23 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.58 Å) | Cite: | Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
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7QO1
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![BU of 7qo1 by Molmil](/molmil-images/mine/7qo1) | complex of DNA ligase I and FEN1 on PCNA and DNA | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ... | Authors: | Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A. | Deposit date: | 2021-12-23 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing. Nat Commun, 13, 2022
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6FCN
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![BU of 6fcn by Molmil](/molmil-images/mine/6fcn) | |
7RPX
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![BU of 7rpx by Molmil](/molmil-images/mine/7rpx) | |
7RPO
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![BU of 7rpo by Molmil](/molmil-images/mine/7rpo) | |
7RPW
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![BU of 7rpw by Molmil](/molmil-images/mine/7rpw) | |