4ULL
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![BU of 4ull by Molmil](/molmil-images/mine/4ull) | SOLUTION NMR STRUCTURE OF VEROTOXIN-1 B-SUBUNIT FROM E. COLI, 5 STRUCTURES | Descriptor: | Shiga toxin 1B | Authors: | Richardson, J.M, Evans, P.D, Homans, S.W, Donohue-Rolfe, A. | Deposit date: | 1996-12-17 | Release date: | 1997-04-01 | Last modified: | 2019-12-11 | Method: | SOLUTION NMR | Cite: | Solution structure of the carbohydrate-binding B-subunit homopentamer of verotoxin VT-1 from E. coli. Nat.Struct.Biol., 4, 1997
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6FE4
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![BU of 6fe4 by Molmil](/molmil-images/mine/6fe4) | |
2XSC
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![BU of 2xsc by Molmil](/molmil-images/mine/2xsc) | Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli | Descriptor: | SHIGA-LIKE TOXIN 1 SUBUNIT B, ZINC ION | Authors: | Stein, P.E, Boodhoo, A, Tyrrell, G.J, Brunton, J.L, Oeffner, R.D, Bunkoczi, G, Read, R.J. | Deposit date: | 2010-09-27 | Release date: | 2010-10-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Crystal Structure of the Cell-Binding B Oligomer of Verotoxin-1 from E. Coli. Nature, 355, 1992
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3MXG
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![BU of 3mxg by Molmil](/molmil-images/mine/3mxg) | Structure of Shiga Toxin type 2 (Stx2) B Pentamer Mutant Q40L | Descriptor: | D-xylose, Shiga-like toxin 2 subunit B | Authors: | Kovall, R.A, Vander Wielen, B.D, Friedmann, D.R, Flagler, M.J. | Deposit date: | 2010-05-07 | Release date: | 2011-01-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2. Plos One, 5, 2010
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1QNU
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![BU of 1qnu by Molmil](/molmil-images/mine/1qnu) | Shiga-Like Toxin I B Subunit Complexed with the Bridged-Starfish Inhibitor | Descriptor: | ETHYL-CARBAMIC ACID METHYL ESTER, METHYL-CARBAMIC ACID ETHYL ESTER, Shiga toxin 1 variant B subunit, ... | Authors: | Pannu, N.S, Hayakawa, K, Read, R.J. | Deposit date: | 1999-10-21 | Release date: | 2000-04-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands. Nature, 403, 2000
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1QOH
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![BU of 1qoh by Molmil](/molmil-images/mine/1qoh) | A MUTANT SHIGA-LIKE TOXIN IIE | Descriptor: | SHIGA-LIKE TOXIN IIE B SUBUNIT | Authors: | Pannu, N.S, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | Deposit date: | 1999-11-08 | Release date: | 2000-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A Mutant Shiga-Like Toxin Iie Bound to its Receptor Gb(3): Structure of a Group II Shiga-Like Toxin with Altered Binding Specificity Structure, 8, 2000
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2C5C
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![BU of 2c5c by Molmil](/molmil-images/mine/2c5c) | |
2BOS
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![BU of 2bos by Molmil](/molmil-images/mine/2bos) | A MUTANT SHIGA-LIKE TOXIN IIE BOUND TO ITS RECEPTOR | Descriptor: | N-BUTANE, PROTEIN (SHIGA-LIKE TOXIN IIE B SUBUNIT), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | Authors: | Ling, H, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | Deposit date: | 1998-10-20 | Release date: | 1999-10-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A mutant Shiga-like toxin IIe bound to its receptor Gb(3): structure of a group II Shiga-like toxin with altered binding specificity. Structure Fold.Des., 8, 2000
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1BOS
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![BU of 1bos by Molmil](/molmil-images/mine/1bos) | SHIGA-LIKE TOXIN COMPLEXED WITH ITS RECEPTOR | Descriptor: | SHIGA-LIKE TOXIN I B SUBUNIT, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Ling, H, Boodhoo, A, Hazes, B, Cummings, M.D, Armstrong, G.D, Brunton, J.L, Read, R.J. | Deposit date: | 1998-01-13 | Release date: | 1999-02-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3. Biochemistry, 37, 1998
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1C48
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![BU of 1c48 by Molmil](/molmil-images/mine/1c48) | MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T) | Descriptor: | PROTEIN (SHIGA-LIKE TOXIN I B SUBUNIT) | Authors: | Ling, H, Bast, D, Brunton, J.L, Read, R.J. | Deposit date: | 1999-08-11 | Release date: | 2000-08-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate To be Published
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1C4Q
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![BU of 1c4q by Molmil](/molmil-images/mine/1c4q) | |
1CZG
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![BU of 1czg by Molmil](/molmil-images/mine/1czg) | |
1CZW
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![BU of 1czw by Molmil](/molmil-images/mine/1czw) | |
1D1I
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![BU of 1d1i by Molmil](/molmil-images/mine/1d1i) | |
1CQF
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![BU of 1cqf by Molmil](/molmil-images/mine/1cqf) | |
1D1K
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![BU of 1d1k by Molmil](/molmil-images/mine/1d1k) | |
6X6H
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![BU of 6x6h by Molmil](/molmil-images/mine/6x6h) | |
6U3U
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![BU of 6u3u by Molmil](/molmil-images/mine/6u3u) | Crystal Structure of Shiga Toxin 2K | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Shiga toxin 2K subunit A, ... | Authors: | Zhang, Y.Z, He, X.H. | Deposit date: | 2019-08-22 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.287 Å) | Cite: | Structural and Functional Characterization of Stx2k, a New Subtype of Shiga Toxin 2. Microorganisms, 8, 2019
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7D6Q
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![BU of 7d6q by Molmil](/molmil-images/mine/7d6q) | Crystal structure of the Stx2a | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 B subunit, rRNA N-glycosylase | Authors: | Takahashi, M, Tamada, M, Hibino, M, Senda, M, Okuda, A, Miyazawa, A, Senda, T, Nishikawa, K. | Deposit date: | 2020-10-01 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin. Commun Biol, 4, 2021
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7D6R
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![BU of 7d6r by Molmil](/molmil-images/mine/7d6r) | Crystal structure of the Stx2a complexed with MMA betaAla peptide | Descriptor: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, MMA betaAla peptide, Shiga toxin 2 B subunit, ... | Authors: | Takahashi, M, Tamada, M, Hibino, M, Senda, M, Okuda, A, Miyazawa, A, Senda, T, Nishikawa, K. | Deposit date: | 2020-10-01 | Release date: | 2021-04-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin. Commun Biol, 4, 2021
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1R4P
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![BU of 1r4p by Molmil](/molmil-images/mine/1r4p) | Shiga toxin type 2 | Descriptor: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, ... | Authors: | Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G. | Deposit date: | 2003-10-07 | Release date: | 2004-05-11 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7. J.Biol.Chem., 279, 2004
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7U6V
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![BU of 7u6v by Molmil](/molmil-images/mine/7u6v) | Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk | Descriptor: | C-terminal domain (CTD) from the Ribosomal P-stalk, Shiga toxin 2a subunit A (Stx2A), Shiga toxin 2a subunit B (Stx2B) | Authors: | Kulczyk, A.W. | Deposit date: | 2022-03-06 | Release date: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. J.Biol.Chem., 299, 2022
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1R4Q
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![BU of 1r4q by Molmil](/molmil-images/mine/1r4q) | Shiga toxin | Descriptor: | SHT cytotoxin A subunit, Shigella toxin chain B | Authors: | Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G. | Deposit date: | 2003-10-07 | Release date: | 2004-05-11 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7. J.Biol.Chem., 279, 2004
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4M1U
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![BU of 4m1u by Molmil](/molmil-images/mine/4m1u) | The crystal structure of Stx2 and a disaccharide ligand | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 A-subunit, ... | Authors: | Yin, J, James, M.N.G, Jacobson, J.M, Kitov, P.I, Bundle, D.R, Mulvey, G, Armstrong, G. | Deposit date: | 2013-08-04 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor. J.Biol.Chem., 289, 2014
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7UJJ
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![BU of 7ujj by Molmil](/molmil-images/mine/7ujj) | Stx2a and DARPin complex | Descriptor: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2022-03-30 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits. Bioengineering (Basel), 9, 2022
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