6ULB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ulb by Molmil](/molmil-images/mine/6ulb) | |
2WJS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wjs by Molmil](/molmil-images/mine/2wjs) | |
3PVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pve by Molmil](/molmil-images/mine/3pve) | Crystal structure of the G2 domain of Agrin from Mus Musculus | Descriptor: | Agrin, Agrin protein | Authors: | Sampathkumar, P, Do, J, Bain, K, Freeman, J, Gheyi, T, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-12-07 | Release date: | 2011-01-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the G2 domain of Agrin from Mus Musculus To be Published
|
|
1D2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1d2s by Molmil](/molmil-images/mine/1d2s) | CRYSTAL STRUCTURE OF THE N-TERMINAL LAMININ G-LIKE DOMAIN OF SHBG IN COMPLEX WITH DIHYDROTESTOSTERONE | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN | Authors: | Grishkovskaya, I, Avvakumov, G.V, Sklenar, G, Dales, D, Hammond, G.L, Muller, Y.A. | Deposit date: | 1999-09-28 | Release date: | 2000-06-28 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain. EMBO J., 19, 2000
|
|
6PYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pya by Molmil](/molmil-images/mine/6pya) | |
6PYF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pyf by Molmil](/molmil-images/mine/6pyf) | Sex Hormone-binding globulin mutant E176K in complex with Estradiol | Descriptor: | CALCIUM ION, ESTRADIOL, Sex hormone-binding globulin | Authors: | Round, P.W, Wu, T.S, Das, S, Van Petegem, F. | Deposit date: | 2019-07-29 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity. J.Biol.Chem., 295, 2020
|
|
6PYB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pyb by Molmil](/molmil-images/mine/6pyb) | Sex Hormone-binding globulin mutant E176K in complex with DVT | Descriptor: | 4,4'-[(3R,4R)-oxolane-3,4-diylbis(methylene)]bis(2-methoxyphenol), CALCIUM ION, Sex hormone-binding globulin | Authors: | Round, P.W, Das, S, Van Petegem, F. | Deposit date: | 2019-07-29 | Release date: | 2019-12-25 | Last modified: | 2020-02-12 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity. J.Biol.Chem., 295, 2020
|
|
1F5F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1f5f by Molmil](/molmil-images/mine/1f5f) | CRYSTAL STRUCTURE OF THE N-TERMINAL G-DOMAIN OF SHBG IN COMPLEX WITH ZINC | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Avvakumov, V.A, Muller, Y.A, Hammond, G.L. | Deposit date: | 2000-06-14 | Release date: | 2000-09-06 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site. J.Biol.Chem., 275, 2000
|
|
1PZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pz9 by Molmil](/molmil-images/mine/1pz9) | Modulation of agrin function by alternative splicing and Ca2+ binding | Descriptor: | Agrin | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | Deposit date: | 2003-07-10 | Release date: | 2004-04-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE, 12, 2004
|
|
1Q56
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q56 by Molmil](/molmil-images/mine/1q56) | NMR structure of the B0 isoform of the agrin G3 domain in its Ca2+ bound state | Descriptor: | Agrin | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | Deposit date: | 2003-08-06 | Release date: | 2004-04-13 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding Structure, 12, 2004
|
|
1PZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pz7 by Molmil](/molmil-images/mine/1pz7) | Modulation of agrin function by alternative splicing and Ca2+ binding | Descriptor: | Agrin, CALCIUM ION | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | Deposit date: | 2003-07-10 | Release date: | 2004-04-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.421 Å) | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE, 12, 2004
|
|
1PZ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pz8 by Molmil](/molmil-images/mine/1pz8) | Modulation of agrin function by alternative splicing and Ca2+ binding | Descriptor: | Agrin, CALCIUM ION | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | Deposit date: | 2003-07-10 | Release date: | 2004-04-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding. STRUCTURE, 12, 2004
|
|
1KDM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kdm by Molmil](/molmil-images/mine/1kdm) | THE CRYSTAL STRUCTURE OF THE HUMAN SEX HORMONE-BINDING GLOBULIN (TETRAGONAL CRYSTAL FORM) | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, sex hormone-binding globulin | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Muller, Y.A. | Deposit date: | 2001-11-13 | Release date: | 2002-05-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site. J.Mol.Biol., 318, 2002
|
|
1LHW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lhw by Molmil](/molmil-images/mine/1lhw) | CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL | Descriptor: | 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Avvakumov, G.V, Grishkovskaya, I, Muller, Y.A, Hammond, G.L. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol. J.Biol.Chem., 277, 2002
|
|
1LHU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lhu by Molmil](/molmil-images/mine/1lhu) | CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH ESTRADIOL | Descriptor: | CALCIUM ION, ESTRADIOL, SEX HORMONE-BINDING GLOBULIN | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
1KDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kdk by Molmil](/molmil-images/mine/1kdk) | THE STRUCTURE OF THE N-TERMINAL LG DOMAIN OF SHBG IN CRYSTALS SOAKED WITH EDTA | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Sex Hormone-Binding Globulin | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Muller, Y.A. | Deposit date: | 2001-11-13 | Release date: | 2002-05-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site. J.Mol.Biol., 318, 2002
|
|
1LHV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lhv by Molmil](/molmil-images/mine/1lhv) | CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH NORGESTREL | Descriptor: | 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
1LHN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lhn by Molmil](/molmil-images/mine/1lhn) | CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17ALPHA-DIOL | Descriptor: | 5-ALPHA-ANDROSTANE-3-BETA,17-ALPHA-DIOL, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN, ... | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
1LHO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lho by Molmil](/molmil-images/mine/1lho) | CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17BETA-DIOL | Descriptor: | 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
5XAU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xau by Molmil](/molmil-images/mine/5xau) | Crystal structure of integrin binding fragment of laminin-511 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Takizawa, M, Arimori, T, Kitago, Y, Takagi, J, Sekiguchi, K. | Deposit date: | 2017-03-15 | Release date: | 2017-09-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanistic basis for the recognition of laminin-511 by alpha 6 beta 1 integrin. Sci Adv, 3, 2017
|
|
5VXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vxz by Molmil](/molmil-images/mine/5vxz) | High-affinity AXL decoy receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Mathrews, I.I, Kapur, S, Kariolis, M.S, Cochran, J.R. | Deposit date: | 2017-05-24 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J. Clin. Invest., 127, 2017
|
|
7CEC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cec by Molmil](/molmil-images/mine/7cec) | Structure of alpha6beta1 integrin in complex with laminin-511 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Arimori, T, Miyazaki, N, Takagi, J. | Deposit date: | 2020-06-22 | Release date: | 2021-06-23 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural mechanism of laminin recognition by integrin. Nat Commun, 12, 2021
|
|
2C5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c5d by Molmil](/molmil-images/mine/2c5d) | Structure of a minimal Gas6-Axl complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | Deposit date: | 2005-10-26 | Release date: | 2005-12-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Basis for Gas6-Axl Signalling. Embo J., 25, 2006
|
|
5MC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mc9 by Molmil](/molmil-images/mine/5mc9) | |
4RA0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ra0 by Molmil](/molmil-images/mine/4ra0) | An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kariolis, M.S, Kapur, S, Mathews, I.I, Cochran, J.R. | Deposit date: | 2014-09-09 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis. Nat.Chem.Biol., 10, 2014
|
|