4FXL
 
 | | Crystal structure of the D76N Beta-2 Microglobulin mutant | | Descriptor: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Ricagno, S, Bellotti, V, Pepys, M.B, Stoppini, M, Bolognesi, M. | | Deposit date: | 2012-07-03 | | Release date: | 2012-08-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Hereditary systemic amyloidosis due to Asp76Asn variant beta-2-microglobulin.
N.Engl.J.Med., 366, 2012
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6O53
 | | Structure of HLA-A2:01 with peptide MM96 | | Descriptor: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | | Authors: | Ying, G, Bitra, A, Zajonc, D.M. | | Deposit date: | 2019-03-01 | | Release date: | 2020-01-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Anin silico-in vitroPipeline Identifying an HLA-A*02:01+KRAS G12V+Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Front Immunol, 10, 2019
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6J2A
 | | The structure of HLA-A*3003/NP44 | | Descriptor: | Beta-2-microglobulin, HLA-A*3003, NP44 | | Authors: | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | | Deposit date: | 2018-12-31 | | Release date: | 2019-09-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides.
Front Immunol, 10, 2019
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5WMQ
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3MRB
 | | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide A7H variant | | Descriptor: | 9-meric peptide from Tegument protein pp65, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Gras, S, Reiser, J.-B, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | | Deposit date: | 2010-04-29 | | Release date: | 2011-05-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structure of MHC class I HLA-A2 molecule complexed with short peptide
To be Published
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1OGA
 | | A structural basis for immunodominant human T-cell receptor recognition. | | Descriptor: | BETA-2-MICROGLOBULIN, GILGFVFTL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | Authors: | Stewart-Jones, G.B.E, McMichael, A.J, Bell, J.I, Stuart, D.I, Jones, E.Y. | | Deposit date: | 2003-04-28 | | Release date: | 2003-06-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A Structural Basis for Immunodominant Human T Cell Receptor Recognition
Nat.Immunol., 4, 2003
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4QRS
 | | Crystal Structure of HLA B*0801 in complex with ELK_IYM, ELKRKMIYM | | Descriptor: | ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Gras, S, Twist, K.-A, Rossjohn, J. | | Deposit date: | 2014-07-02 | | Release date: | 2014-12-10 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
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4QRT
 | | Crystal Structure of HLA B*0801 in complex with ELN_YYM, ELNRKMIYM | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Gras, S, Twist, K.-A, Rossjohn, J. | | Deposit date: | 2014-07-02 | | Release date: | 2014-07-16 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
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4RAH
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6TDP
 | | Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GL dipeptide in the A pocket. | | Descriptor: | Beta-2-microglobulin, GLYCEROL, GLYCINE, ... | | Authors: | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | | Deposit date: | 2019-11-10 | | Release date: | 2020-03-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.
Nat Commun, 11, 2020
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1I4F
 | | CRYSTAL STRUCTURE OF HLA-A*0201/MAGE-A4-PEPTIDE COMPLEX | | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | Authors: | Hillig, R.C, Coulie, P.G, Stroobant, V, Saenger, W, Ziegler, A, Huelsmeyer, M. | | Deposit date: | 2001-02-21 | | Release date: | 2001-07-25 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | High-resolution structure of HLA-A*0201 in complex with a tumour-specific antigenic peptide encoded by the MAGE-A4 gene.
J.Mol.Biol., 310, 2001
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3MRK
 | | Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide | | Descriptor: | 9-meric peptide from Alpha-fetoprotein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Gras, S, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | | Deposit date: | 2010-04-29 | | Release date: | 2011-05-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structure of MHC class I HLA-A2 molecule complexed with AFP137 nonapeptide
To be Published
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4RMW
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4RMU
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2A83
 | | Crystal structure of hla-b*2705 complexed with the glucagon receptor (gr) peptide (residues 412-420) | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | Authors: | Ruckert, C, Fiorillo, M.T, Loll, B, Moretti, R, Biesiadka, J, Saenger, W, Ziegler, A, Sorrentino, R, Uchanska-Ziegler, B. | | Deposit date: | 2005-07-07 | | Release date: | 2005-12-27 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype.
J.Biol.Chem., 281, 2006
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7X1C
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6VB2
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4XXC
 | | HLA-B*1801 in complex with a self-peptide, DELEIKAY | | Descriptor: | ACETATE ION, ASP-GLU-LEU-GLU-ILE-LYS-ALA-TYR, Beta-2-microglobulin, ... | | Authors: | Hibbert, K.M, Rossjohn, J, Gras, S. | | Deposit date: | 2015-01-30 | | Release date: | 2015-04-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.426 Å) | | Cite: | T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells.
J Immunol., 194, 2015
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5IB2
 | | Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | Authors: | Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. | | Deposit date: | 2016-02-22 | | Release date: | 2017-02-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
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6PYJ
 | | Crystal Structure of HLA-B*2705 in complex with LRN, a self-peptide | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | | Authors: | Gras, S. | | Deposit date: | 2019-07-30 | | Release date: | 2019-12-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
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7M8U
 | | Crystal Structure of HLA-B*35:01 in complex with IPFAMQMAY, an 9-mer epitope from SARS-CoV-2 spike (S896-904) | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen B, alpha chain, ... | | Authors: | Gras, S, Nguyen, A.T, Szeto, C. | | Deposit date: | 2021-03-30 | | Release date: | 2021-06-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | SARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules
Biophysica, 1, 2021
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8RNG
 | | Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGNESIUM ION, ... | | Authors: | Murdolo, L.D, Maddumage, J.C, Gras, S. | | Deposit date: | 2024-01-10 | | Release date: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of HLA B*18:01 in complex with TEVETYVL, an 8-mer epitope from Influenza A
To Be Published
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1X7Q
 | | Crystal structure of HLA-A*1101 with sars nucleocapsid peptide | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | Authors: | Blicher, T, Kastrup, J.S, Buus, S, Gajhede, M. | | Deposit date: | 2004-08-16 | | Release date: | 2005-08-02 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide.
Acta Crystallogr.,Sect.D, 61, 2005
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6PYV
 | | Crystal Structure of HLA-B*2703-P47G in complex with LRN, a self-peptide | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-2703 alpha chain, ... | | Authors: | Gras, S. | | Deposit date: | 2019-07-31 | | Release date: | 2019-11-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
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6BXP
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