6EMR
 
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6EMP
 | | Solution structure of the LEDGF/p75 IBD - POGZ (aa 1370-1404) complex | | Descriptor: | PC4 and SFRS1-interacting protein,Pogo transposable element with ZNF domain | | Authors: | Veverka, V. | | Deposit date: | 2017-10-03 | | Release date: | 2018-07-25 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EMO
 | | Solution structure of the LEDGF/p75 IBD - JPO2 (aa 1-32) complex | | Descriptor: | PC4 and SFRS1-interacting protein,LEDGF/p75 IBD-JPO2 M1 | | Authors: | Veverka, V. | | Deposit date: | 2017-10-03 | | Release date: | 2018-07-25 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EMQ
 | | Solution structure of the LEDGF/p75 IBD - MLL1 (aa 111-160) complex | | Descriptor: | PC4 and SFRS1-interacting protein,Histone-lysine N-methyltransferase 2A | | Authors: | Veverka, V. | | Deposit date: | 2017-10-03 | | Release date: | 2018-08-01 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6ZV0
 | | TFIIS N-terminal domain (TND) from human LEDGF/p75 | | Descriptor: | PC4 and SFRS1-interacting protein | | Authors: | Veverka, V. | | Deposit date: | 2020-07-23 | | Release date: | 2021-12-01 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | A ubiquitous disordered protein interaction module orchestrates transcription elongation.
Science, 374, 2021
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2M16
 | | P75/LEDGF PWWP Domain | | Descriptor: | PC4 and SFRS1-interacting protein | | Authors: | Crowe, B.L, Foster, M.P. | | Deposit date: | 2012-11-18 | | Release date: | 2013-02-27 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.
Nucleic Acids Res., 41, 2013
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2MSR
 | | Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160) | | Descriptor: | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein | | Authors: | Cermakova, K, Tesina, P, Demeulemeester, J, El Ashkar, S, Mereau, H, Schwaller, J, Rezacova, P, Veverka, V, De Rijck, J. | | Deposit date: | 2014-08-05 | | Release date: | 2014-08-20 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Validation and Structural Characterization of the LEDGF/p75-MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia.
Cancer Res., 74, 2014
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2MTN
 | | Solution structure of MLL-IBD complex | | Descriptor: | Histone-lysine N-methyltransferase 2A, PC4 and SFRS1-interacting protein fusion | | Authors: | Cierpicki, T, Pollock, J, Murai, M. | | Deposit date: | 2014-08-23 | | Release date: | 2014-12-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Blood, 124, 2014
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2N3A
 | | Solution structure of LEDGF/p75 IBD in complex with POGZ peptide (1389-1404) | | Descriptor: | PC4 and SFRS1-interacting protein, Pogo transposable element with ZNF domain | | Authors: | Tesina, P, Cermakova, K, Horejsi, M, Prochazkova, K, Fabry, M, Sharma, S, Christ, F, Demeulemeester, J, Debyser, Z, De Rijck, J, Veverka, V, Rezacova, P. | | Deposit date: | 2015-05-26 | | Release date: | 2015-08-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.
Nat Commun, 6, 2015
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