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7TJK
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BU of 7tjk by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with docked Orc6 N-terminal domain
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
著者Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
登録日2022-01-16
公開日2022-10-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJJ
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BU of 7tjj by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with docked Orc6 N-terminal domain
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
著者Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
登録日2022-01-16
公開日2022-10-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJI
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BU of 7tji by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
著者Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
登録日2022-01-16
公開日2022-10-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJH
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BU of 7tjh by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
著者Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
登録日2022-01-16
公開日2022-10-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJF
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BU of 7tjf by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA, 84 bp ARS1, ...
著者Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
登録日2022-01-16
公開日2023-01-18
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7MCA
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BU of 7mca by Molmil
Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.
分子名称: Cell division control protein 6, DNA (85-MER), MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2021-04-01
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun, 12, 2021
7JPS
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BU of 7jps by Molmil
ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPR
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BU of 7jpr by Molmil
ORC-OPEN: Human Origin Recognition Complex (ORC) in an open conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPQ
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BU of 7jpq by Molmil
ORC-O2-5: Human Origin Recognition Complex (ORC) with subunits 2,3,4,5
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 2, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPP
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BU of 7jpp by Molmil
ORC-O2WH: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC1 AAA+ domain
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JPO
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BU of 7jpo by Molmil
ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
著者Jaremko, M.J, Joshua-Tor, L.
登録日2020-08-09
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
7JK6
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BU of 7jk6 by Molmil
Structure of Drosophila ORC in the active conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK5
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BU of 7jk5 by Molmil
Structure of Drosophila ORC bound to DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (32-MER), MAGNESIUM ION, ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK4
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BU of 7jk4 by Molmil
Structure of Drosophila ORC bound to AT-rich DNA and Cdc6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (34-MER), ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK3
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BU of 7jk3 by Molmil
Structure of Drosophila ORC bound to GC-rich DNA and Cdc6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK2
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BU of 7jk2 by Molmil
Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-27
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JGS
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BU of 7jgs by Molmil
Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 2)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-19
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JGR
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BU of 7jgr by Molmil
Structure of Drosophila ORC bound to DNA (84 bp) and Cdc6
分子名称: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ...
著者Schmidt, J.M, Bleichert, F.
登録日2020-07-19
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7CTG
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BU of 7ctg by Molmil
Human Origin Recognition Complex, ORC1-5 State I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
7CTF
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BU of 7ctf by Molmil
Human origin recognition complex 1-5 State II
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
7CTE
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BU of 7cte by Molmil
Human Origin Recognition Complex, ORC2-5
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
6WGI
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BU of 6wgi by Molmil
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution
分子名称: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGG
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BU of 6wgg by Molmil
Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
分子名称: Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGC
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BU of 6wgc by Molmil
Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
分子名称: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6RQC
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BU of 6rqc by Molmil
Cryo-EM structure of an MCM loading intermediate
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ...
著者Miller, T.C.R, Locke, J, Costa, A.
登録日2019-05-15
公開日2019-11-20
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Nature, 575, 2019

 

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