9EQG
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9AWK
| Bovine fetal muscle nAChR resting state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Li, H, Hibbs, R.E. | 登録日 | 2024-03-05 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-18 | 実験手法 | ELECTRON MICROSCOPY (2.14 Å) | 主引用文献 | Structural switch in acetylcholine receptors in developing muscle. Nature, 632, 2024
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9AWJ
| Bovine adult muscle nAChR bound to ACh | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, ... | 著者 | Li, H, Hibbs, R.E. | 登録日 | 2024-03-05 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-18 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structural switch in acetylcholine receptors in developing muscle. Nature, 632, 2024
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9AVV
| Bovine adult muscle nAChR resting state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ... | 著者 | Li, H, Hibbs, R.E. | 登録日 | 2024-03-05 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-18 | 実験手法 | ELECTRON MICROSCOPY (2.09 Å) | 主引用文献 | Structural switch in acetylcholine receptors in developing muscle. Nature, 632, 2024
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9AVU
| Bovine fetal muscle nAChR bound to ACh | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, ... | 著者 | Li, H, Hibbs, R.E. | 登録日 | 2024-03-05 | 公開日 | 2024-07-31 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structural switch in acetylcholine receptors in developing muscle. Nature, 632, 2024
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8ZFM
| Caenorhabditis elegans ACR-23 in betaine bound state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ... | 著者 | Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S. | 登録日 | 2024-05-08 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine To Be Published
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8ZFL
| Caenorhabditis elegans ACR-23 in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562 | 著者 | Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S. | 登録日 | 2024-05-08 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine To Be Published
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8ZFK
| Caenorhabditis elegans ACR-23 in betaine and monepantel bound state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ... | 著者 | Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S. | 登録日 | 2024-05-08 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine To Be Published
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8VRN
| Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus PPTQ | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(4-methylphenyl)-2-phenylquinazolin-4(3H)-one, ... | 著者 | Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E. | 登録日 | 2024-01-22 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Structural insights into GABA A receptor potentiation by Quaalude. Nat Commun, 15, 2024
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8VQY
| Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus methaqualone | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one, GAMMA-AMINO-BUTANOIC ACID, ... | 著者 | Chojnacka, W, Teng, J, Kim, J.J, Jensen, A.A, Hibbs, R.E. | 登録日 | 2024-01-19 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Structural insights into GABA A receptor potentiation by Quaalude. Nat Commun, 15, 2024
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8V8D
| Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 asymmetric state 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V8C
| Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 asymmetric state 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V8A
| Alpha7-nicotinic acetylcholine receptor time resolved bound to epibatidine and PNU-120596 desensitized intermediate state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V89
| Alpha7-nicotinic acetylcholine receptor time resolved resting state | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V88
| Alpha7-nicotinic acetylcholine receptor bound to epibatidine and GAT107 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-05 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V86
| Alpha7-nicotinic acetylcholine receptor bound to GAT107 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V82
| Alpha7-nicotinic acetylcholine receptor bound to epibatidine and PNU-120596 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8V80
| Alpha7-nicotinic acetylcholine receptor bound to epibatidine and (-)-TQS | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3aR,4S,9bS)-4-(naphthalen-1-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-12-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8UZJ
| Alpha7-nicotinic acetylcholine receptor bound to epibatidine and ivermectin | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-11-15 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8UTB
| Alpha7-nicotinic acetylcholine receptor bound to epibatidine and NS-1738 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Noviello, C.M, Hibbs, R.E. | 登録日 | 2023-10-30 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8UT1
| Alpha7-nicotinic acetylcholine receptor bound to epibatidine | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Burke, S.M, Hibbs, R.E, Noviello, C.M. | 登録日 | 2023-10-30 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural mechanisms of alpha 7 nicotinic receptor allosteric modulation and activation. Cell, 187, 2024
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8ST4
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8ST3
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8ST2
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8ST1
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