PDB: 173 件ウェブページステータス検索Chemie searchBIRD

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3CAK	X-ray structure of WT PTE with ethyl phosphate 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, ... 著者 Kim, J, Tsai, P.-C, Almo, S.C, Raushel, F.M. 登録日 2008-02-20 公開日 2008-10-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase. Biochemistry, 47, 2008
7P85	Engineered phosphotriesterase BdPTE 10-2-C3(C59V/C227V) in complex with ethyl-4-methylbenzylphosphonate 分子名称: FORMIC ACID, GLYCEROL, Parathion hydrolase, ... 著者 Eichinger, A, Skerra, A. 登録日 2021-07-21 公開日 2022-08-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop. Biochemistry, 62, 2023
5CH9	Gkap mutant B12 分子名称: COBALT (II) ION, Phosphotriesterase 著者 Chen, L.-Q. 登録日 2015-07-10 公開日 2015-09-09 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Active site loop architecture enhance the promiscuous PTE activity in lactonase from Geobacillus kaustophilus HTA426 To Be Published
4E3T	Round 18 Arylesterase Variant of Phosphotriesterase with Bound Transition State Analog 分子名称: Phosphotriesterase, ZINC ION, hexyl(naphthalen-2-yloxy)phosphinic acid 著者 Tokuriki, N, Jackson, C.J, Tawfik, D.S. 登録日 2012-03-10 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme Nat Commun, 3, 2012
1HZY	HIGH RESOLUTION STRUCTURE OF THE ZINC-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA 分子名称: 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, FORMIC ACID, ... 著者 Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. 登録日 2001-01-26 公開日 2001-04-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
6AML	Phosphotriesterase variant S8 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... 著者 Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. 登録日 2017-08-09 公開日 2018-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Phosphotriesterase variant S8 To Be Published
2VC7	Structural basis for natural lactonase and promiscuous phosphotriesterase activities 分子名称: (4S)-4-(decanoylamino)-5-hydroxy-3,4-dihydro-2H-thiophenium, 1,2-ETHANEDIOL, ARYLDIALKYLPHOSPHATASE, ... 著者 Elias, M, Dupuy, J, Merone, L, Mandrich, L, Moniot, S, Rochu, D, Lecomte, C, Rossi, M, Masson, P, Manco, G, Chabriere, E. 登録日 2007-09-19 公開日 2008-04-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. J.Mol.Biol., 379, 2008
4WVX	Crystal structure of a phosphotriesterase-like lactonase Gkap in native form 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, Phosphotriesterase 著者 An, J, Zhang, Y, Yang, G.Y, Feng, Y. 登録日 2014-11-07 公開日 2015-11-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides To Be Published
4ZSU	Crystal structure of Brevundimonas diminuta phosphotriesterase mutant L7eP-3aG 分子名称: COBALT (II) ION, Parathion hydrolase 著者 Mabanglo, M.F, Raushel, F.M. 登録日 2015-05-14 公開日 2015-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.011 Å) 主引用文献 Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR. Biochemistry, 54, 2015
4ZST	Crystal structure of Brevundimonas diminuta phosphotriesterase mutant L7eP-3a 分子名称: COBALT (II) ION, Parathion hydrolase 著者 Mabanglo, M.F, Raushel, F.M. 登録日 2015-05-13 公開日 2015-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.011 Å) 主引用文献 Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR. Biochemistry, 54, 2015
4XAY	Cycles of destabilization and repair underlie evolutionary transitions in enzymes 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R8, ... 著者 Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. 登録日 2014-12-16 公開日 2015-12-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The role of protein dynamics in the evolution of new enzyme function. Nat.Chem.Biol., 12, 2016
2VC5	Structural basis for natural lactonase and promiscuous phosphotriesterase activities 分子名称: 1,2-ETHANEDIOL, ARYLDIALKYLPHOSPHATASE, COBALT (II) ION, ... 著者 Elias, M, Dupuy, J, Merone, L, Mandrich, L, Moniot, S, Lecomte, C, Rossi, M, Masson, P, Manco, G, Chabriere, E. 登録日 2007-09-18 公開日 2008-04-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. J.Mol.Biol., 379, 2008
2R1P	OpdA from Agrobacterium radiobacter with bound product diethyl thiophosphate from co-crystallisation with tetraethyl dithiopyrophosphate- 1.8 A 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ... 著者 Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. 登録日 2007-08-23 公開日 2008-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
1I0B	HIGH RESOLUTION STRUCTURE OF THE MANGANESE-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA 分子名称: 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, FORMIC ACID, ... 著者 Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. 登録日 2001-01-29 公開日 2001-04-04 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
1I0D	HIGH RESOLUTION STRUCTURE OF THE ZINC/CADMIUM-CONTAINING PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA 分子名称: 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, CADMIUM ION, ... 著者 Holden, H.M, Benning, M.M, Raushel, F.M, Shim, H. 登録日 2001-01-29 公開日 2001-04-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
2R1M	OpdA from Agrobacterium radiobacter with bound product diethyl phosphate from crystal soaking with diethyl 4-methoxyphenyl phosphate (450h)- 2.5 A 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, ... 著者 Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. 登録日 2007-08-23 公開日 2008-02-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
2D2H	OpdA from Agrobacterium radiobacter with bound inhibitor trimethyl phosphate at 1.8 A resolution 分子名称: COBALT (II) ION, TRIMETHYL PHOSPHATE, phosphotriesterase 著者 Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. 登録日 2005-09-09 公開日 2005-09-20 最終更新日 2015-08-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
2R1K	OpdA from Agrobacterium radiobacter with bound diethyl phosphate from crystal soaking with the compound- 1.9 A 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, ... 著者 Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. 登録日 2007-08-23 公開日 2008-02-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase J.Mol.Biol., 375, 2008
6JSS	Structure of Geobacillus kaustophilus lactonase, Y99P mutant 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Yew, W.S. 登録日 2019-04-08 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily. Structure, 28, 2020
1JGM	High Resolution Structure of the Cadmium-containing Phosphotriesterase from Pseudomonas diminuta 分子名称: 1,2-ETHANEDIOL, 2-PHENYL-ETHANOL, CADMIUM ION, ... 著者 Benning, M.M, Shim, H, Raushel, F.M, Holden, H.M. 登録日 2001-06-26 公開日 2001-07-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 High resolution X-ray structures of different metal-substituted forms of phosphotriesterase from Pseudomonas diminuta. Biochemistry, 40, 2001
6JSU	Structure of Geobacillus kaustophilus lactonase, Y99C/D266N double mutant 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Yew, W.S. 登録日 2019-04-08 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily. Structure, 28, 2020
6JST	Structure of Geobacillus kaustophilus lactonase, Y99P/D266N double mutant with bound 3-oxo-C8-HSL 分子名称: 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE, FE (III) ION, HYDROXIDE ION, ... 著者 Xue, B, Yew, W.S. 登録日 2019-04-08 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.726 Å) 主引用文献 Directed Computational Evolution of Quorum-Quenching Lactonases from the Amidohydrolase Superfamily. Structure, 28, 2020
2D2J	OpdA from Agrobacterium radiobacter without inhibitor/product present at 1.75 A resolution 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, phosphotriesterase 著者 Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. 登録日 2005-09-09 公開日 2005-09-20 最終更新日 2015-08-19 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
2D2G	OpdA from Agrobacterium radiobacter with bound product dimethylthiophosphate 分子名称: COBALT (II) ION, O,O-DIMETHYL HYDROGEN THIOPHOSPHATE, phosphotriesterase 著者 Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. 登録日 2005-09-08 公開日 2005-09-20 最終更新日 2015-08-19 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
3TN3	Crystal structure of GkaP from Geobacillus kaustophilus HTA426 分子名称: COBALT (II) ION, Phosphotriesterase 著者 An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. 登録日 2011-09-01 公開日 2012-09-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published

 

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