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8Y2S
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P-hydroxybenzoate hydroxylase complexed with 4-hydroxy-3-methylbenzoic acid
分子名称: 3-methyl-4-oxidanyl-benzoic acid, 4-hydroxybenzoate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Hara, K, Hashimoto, H, Matsushita, T, Kishimoto, S, Watanabe, K.
登録日2024-01-27
公開日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Functional Enhancement of Flavin-Containing Monooxygenase through Machine Learning Methodology
Acs Catalysis, 14, 2024
3C96
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Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase
著者Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2008-02-15
公開日2008-02-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa.
To be Published
6LKD
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BU of 6lkd by Molmil
in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor
分子名称: 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Mimasu, S, Yamagishi, H, Kiyohara, M, Kakefuda, K, Okuda, T.
登録日2019-12-19
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.
Commun Biol, 4, 2021
8GSM
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BU of 8gsm by Molmil
Crystal Structure of VibMO1
分子名称: 4-hydroxybenzoate decarboxylase, FLAVIN-ADENINE DINUCLEOTIDE
著者Ying, Z, Feng, K.N.
登録日2022-09-06
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Crystal Structure of VibMO1
To Be Published
1YKJ
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A45G p-hydroxybenzoate hydroxylase with p-hydroxybenzoate bound
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, P-hydroxybenzoate hydroxylase, ...
著者Cole, L.J, Gatti, D.L, Entsch, B, Ballou, D.P.
登録日2005-01-18
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase.
Biochemistry, 44, 2005
8WVB
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BU of 8wvb by Molmil
Crystal structure of Lsd18 mutant S195M
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC
著者Liu, N, Xiao, H.L, Chen, X.
登録日2023-10-23
公開日2023-12-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A.
Int J Mol Sci, 24, 2023
8WVF
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Crystal structure of Lsd18 mutant T189M and S195M
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative epoxidase LasC
著者Liu, N, Xiao, H.L, Chen, X.
登録日2023-10-23
公開日2023-12-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.757 Å)
主引用文献Simultaneous Improvement in the Thermostability and Catalytic Activity of Epoxidase Lsd18 for the Synthesis of Lasalocid A.
Int J Mol Sci, 24, 2023
7MWA
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BU of 7mwa by Molmil
Crystal structure of 2-octaprenyl-6-methoxyphenol hydroxylase UbiH from Acinetobacter baumannii, apoenzyme
分子名称: 1,2-ETHANEDIOL, 2-polyprenyl-6-methoxyphenol 4-hydroxylase, CHLORIDE ION, ...
著者Stogios, P.J, Evdokimova, E, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-05-16
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献UbiH from Acinetobacter baumannii
To Be Published
8ER1
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X-ray crystal structure of Tet(X6)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase
著者Kumar, H, Tolia, N.H.
登録日2022-10-11
公開日2023-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
8ER0
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X-ray crystal structure of Tet(X6) bound to anhydrotetracycline
分子名称: 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase
著者Kumar, H, Tolia, N.H.
登録日2022-10-11
公開日2023-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
3P9U
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BU of 3p9u by Molmil
Crystal structure of TetX2 from Bacteroides thetaiotaomicron with substrate analogue
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TetX2 protein
著者Walkiewicz, K, Davlieva, M, Sun, C, Lau, K, Shamoo, Y.
登録日2010-10-18
公開日2011-04-27
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal structure of Bacteroides thetaiotaomicron TetX2: a tetracycline degrading monooxygenase at 2.8 A resolution.
Proteins, 79, 2011
3OZ2
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BU of 3oz2 by Molmil
Crystal structure of a geranylgeranyl bacteriochlorophyll reductase-like (Ta0516) from Thermoplasma acidophilum at 1.60 A resolution
分子名称: (2R)-3-{[(R)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-[(6Z)-tridec-6-enoyloxy]propyl (9Z)-octadec-9-enoate, 1,2-ETHANEDIOL, Digeranylgeranylglycerophospholipid reductase, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-09-24
公開日2010-10-27
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
J.Mol.Biol., 404, 2010
2RGJ
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BU of 2rgj by Molmil
Crystal structure of flavin-containing monooxygenase PhzS
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Flavin-containing monooxygenase
著者Ladner, J.E, Parsons, J.F, Greenhagen, B.T, Robinson, H.
登録日2007-10-03
公開日2008-05-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Pyocyanin Biosynthetic Protein PhzS.
Biochemistry, 47, 2008
5FN0
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BU of 5fn0 by Molmil
Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180
分子名称: 3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, KYNURENINE 3-MONOOXYGENASE
著者Mole, D.J, Webster, S.P, Uings, I, Zheng, X, Binnie, M, Wilson, K, Hutchinson, J.P, Mirguet, O, Walker, A, Beaufils, B, Ancellin, N, Trottet, L, Beneton, V, Mowat, C.G, Wilkinson, M, Rowland, P, Haslam, C, McBride, A, Homer, N.Z.M, Baily, J.E, Sharp, M.G.F, Garden, O.J, Hughes, J, Howie, S.E.M, Holmes, D, Liddle, J, Iredale, J.P.
登録日2015-11-10
公開日2016-01-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Kynurenine-3-Monooxygenase Inhibition Prevents Multiple Organ Failure in Rodent Models of Acute Pancreatitis.
Nat.Med. (N.Y.), 22, 2016
3RP7
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BU of 3rp7 by Molmil
Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD and uric acid
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIC ACID, flavoprotein monooxygenase
著者Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
登録日2011-04-26
公開日2012-05-16
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (2.042 Å)
主引用文献Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
3RP8
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Crystal Structure of Klebsiella pneumoniae R204Q HpxO complexed with FAD
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase
著者Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
登録日2011-04-26
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
5HYM
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BU of 5hym by Molmil
3-Hydroxybenzoate 6-hydroxylase from Rhodococcus jostii in complex with phosphatidylinositol
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Phosphatidylinositol, ...
著者Orru, R, Montersino, S, Mattevi, A, van Berkel, W.J.H.
登録日2016-02-01
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.
Front Microbiol, 8, 2017
2X3N
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BU of 2x3n by Molmil
Crystal structure of pqsL, a probable FAD-dependent monooxygenase from Pseudomonas aeruginosa
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PROBABLE FAD-DEPENDENT MONOOXYGENASE
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
登録日2010-01-25
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2VOU
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BU of 2vou by Molmil
Structure of 2,6-dihydroxypyridine-3-hydroxylase from Arthrobacter nicotinovorans
分子名称: 2,6-DIHYDROXYPYRIDINE HYDROXYLASE, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Treiber, N, Schulz, G.E.
登録日2008-02-21
公開日2008-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of 2,6-Dihydroxypyridine 3-Hydroxylase from a Nicotine-Degrading Pathway.
J.Mol.Biol., 379, 2008
8UIV
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H47Q NicC with bound FAD
分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Hicks, K.A, Perry, K.
登録日2023-10-10
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
Arch.Biochem.Biophys., 752, 2024
8UIQ
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H47Q NicC with 2-mercaptopyridine ligand
分子名称: 2-PYRIDINETHIOL, 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Hicks, K.A, Perry, K, Turlington, Z.R, Vaz Ferreira de Macedo, S.
登録日2023-10-10
公開日2024-02-21
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
Arch.Biochem.Biophys., 752, 2024
3RP6
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Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase
著者Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E.
登録日2011-04-26
公開日2012-05-16
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
5HXI
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2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5HN bound
分子名称: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, 5-hydroxypyridine-3-carboxylic acid, BETA-MERCAPTOETHANOL, ...
著者Kobayashi, J, Mikami, B.
登録日2016-01-30
公開日2016-10-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Role of the Tyr270 residue in 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase from Mesorhizobium loti
J. Biosci. Bioeng., 123, 2017
8RQH
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Crystal Structure of the flavoprotein monooxygenase TrlE from Streptomyces cyaneofuscatus Soc7
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
著者Sowa, S.T, Hoeing, L.S, Jakob, R.P, Maier, T, Teufel, R.
登録日2024-01-18
公開日2024-05-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biosynthesis of the bacterial antibiotic 3,7-dihydroxytropolone through enzymatic salvaging of catabolic shunt products.
Chem Sci, 15, 2024
6JU1
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p-Hydroxybenzoate hydroxylase Y385F mutant complexed with 3,4-dihydroxybenzoate
分子名称: 3,4-DIHYDROXYBENZOIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-hydroxybenzoate 3-monooxygenase, ...
著者Yato, M, Arakawa, T, Yamada, C, Fushinobu, S.
登録日2019-04-12
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Understanding the Molecular Mechanism Underlying the High Catalytic Activity ofp-Hydroxybenzoate Hydroxylase Mutants for Producing Gallic Acid.
Biochemistry, 58, 2019

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