PDB: 65 件ウェブページステータス検索Chemie searchBIRD

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7HI8	PanDDA analysis group deposition -- Crystal Structure of ground state model of human Brachyury 分子名称: CADMIUM ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2024-09-20 公開日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 PanDDA analysis group deposition To Be Published
7HI9	PanDDA analysis group deposition of ground-state model of human Brachyury G177D variant 分子名称: SODIUM ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2024-09-20 公開日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 PanDDA analysis group deposition of ground-state model To Be Published
8CDN	Crystal structure of human Brachyury in complex with a single T box binding element DNA 分子名称: DNA (5'-D(*AP*GP*GP*CP*TP*CP*AP*CP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*GP*TP*GP*AP*GP*CP*CP*T)-3'), T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, von Delft, F, Gileadi, O, Bountra, C. 登録日 2023-01-31 公開日 2023-03-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of human Brachyury in complex with a single T box binding element DNA To Be Published
8FMU	Crystal structure of human Brachyury G177D variant in complex with SJF-4601 分子名称: N-(3-chloro-4-fluorophenyl)-3-[4-(dimethylamino)butanamido]-4-methoxybenzamide, T-box transcription factor T 著者 Bebenek, A, Linhares, B, Jaime-Figueroa, S, Butrin, A, Crews, C. 登録日 2022-12-24 公開日 2024-02-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury. Angew.Chem.Int.Ed.Engl., 63, 2024
8A7N	Crystal Structure of human Brachyury G177D variant in complex with (S)-N-(3-aminopropyl)-3-((1-(2-fluorophenyl)-2-oxopyrrolidin-3-yl)amino)-N-methylbenzamide (CF-2-125) 分子名称: N-(3-azanylpropyl)-3-[[(3S)-1-(2-fluorophenyl)-2-oxidanylidene-pyrrolidin-3-yl]amino]-N-methyl-benzamide, PHOSPHATE ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-06-21 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with (S)-N-(3-aminopropyl)-3-((1-(2-fluorophenyl)-2-oxopyrrolidin-3-yl)amino)-N-methylbenzamide (CF-2-125) To Be Published
8A10	Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143 分子名称: T-box transcription factor T, UNKNOWN LIGAND 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-05-30 公開日 2022-07-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143 To Be Published
7ZL2	Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810 分子名称: T-box transcription factor T, UNKNOWN LIGAND 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-04-13 公開日 2022-06-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810 To Be Published
7ZKF	Crystal Structure of human Brachyury G177D variant in complex with CF-5-86 分子名称: PHOSPHATE ION, T-box transcription factor T, UNKNOWN LIGAND 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-04-12 公開日 2022-06-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with CF-5-86 To Be Published
7ZK2	Crystal Structure of human Brachyury G177D variant in complex with CSC027898502 分子名称: N-[4-(2-morpholin-4-yl-1,3-thiazol-4-yl)phenyl]ethanamide, PHOSPHATE ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-04-12 公開日 2022-06-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with CSC027898502 To Be Published
6ZU8	Crystal structure of human Brachyury G177D variant in complex with Afatinib 分子名称: Brachyury protein, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide, ZINC ION 著者 Newman, J.A, Gavard, A.E, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2020-07-21 公開日 2020-08-05 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of human Brachyury G177D variant in complex with Afatinib To Be Published
5QS6	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z44592329 分子名称: N-phenyl-N'-pyridin-3-ylurea, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Fernandez-Cid, A, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-06-19 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QT0	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z321318226 分子名称: N-(4-methoxyphenyl)-N'-pyridin-4-ylurea, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-26 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QRH	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z32327641 分子名称: CADMIUM ION, T-box transcription factor T, [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QS7	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z32327641 分子名称: T-box transcription factor T, [4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QSL	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1273312153 分子名称: CADMIUM ION, N-methyl-1H-indole-7-carboxamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QSK	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434906 分子名称: (benzyloxy)acetic acid, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QRI	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z2856434826 分子名称: CADMIUM ION, T-box transcription factor T, [4-(propan-2-yl)piperazin-1-yl](thiophen-2-yl)methanone 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QS9	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z48847594 分子名称: N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QRM	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1899842917 分子名称: 3-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-5-methyl-1,3,4-thiadiazol-2(3H)-one, CADMIUM ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QSD	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z54571979 分子名称: N-{4-[(pyrimidin-2-yl)oxy]phenyl}acetamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QRK	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z275179758 分子名称: CADMIUM ION, N-[(1-methyl-1H-pyrazol-4-yl)methyl]furan-2-carboxamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QSC	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z300245038 分子名称: N-[(3-fluorophenyl)methyl]-N-methylsulfuric diamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QRN	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z54226006 分子名称: (2,6-difluorophenyl)(pyrrolidin-1-yl)methanone, CADMIUM ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QSF	PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434814 分子名称: 3-(diethylamino)phenol, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-08-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 PanDDA analysis group deposition To Be Published
5QRS	PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1891773393 分子名称: CADMIUM ION, N-{4-[(1S)-1-aminoethyl]phenyl}cyclopropanecarboxamide, T-box transcription factor T 著者 Newman, J.A, Gavard, A.E, Fernandez-Cid, A, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-05-25 公開日 2019-07-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 PanDDA analysis group deposition To Be Published

 

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