PDB: 216 件ウェブページステータス検索Chemie searchBIRD

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8HYI	Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine 分子名称: 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... 著者 Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. 登録日 2023-01-06 公開日 2023-08-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Modulation of a conformational ensemble by a small molecule that inhibits key protein-protein interactions involved in cell adhesion. Protein Sci., 32, 2023
2QVI	Crystal structure of N-cadherin domains EC12 分子名称: CALCIUM ION, Cadherin-2 著者 Shapiro, L.S, Carroll, K.J. 登録日 2007-08-08 公開日 2008-08-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.012 Å) 主引用文献 Biophysical characterization of N-cadherin and E-cadherin homophilic and heterophilic interactions To be Published
3UBG	Crystal structure of Drosophila N-cadherin EC1-3, II 分子名称: CALCIUM ION, Neural-cadherin, ZINC ION 著者 Jin, X, Walker, M.A, Shapiro, L. 登録日 2011-10-24 公開日 2011-12-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers. Proc.Natl.Acad.Sci.USA, 109, 2012
1FF5	STRUCTURE OF E-CADHERIN DOUBLE DOMAIN 分子名称: CALCIUM ION, EPITHELIAL CADHERIN 著者 Pertz, O, Bozic, D, Koch, A.W, Fauser, C, Brancaccio, A, Engel, J. 登録日 2000-07-25 公開日 2000-08-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation. EMBO J., 18, 1999
4NQQ	Crystal structure of mouse P-cadherin extracellular domains EC1-EC2 分子名称: CALCIUM ION, COPPER (II) ION, Cadherin-3 著者 Brasch, J, Shapiro, L. 登録日 2013-11-25 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and energetic determinants of adhesive binding specificity in type I cadherins. Proc.Natl.Acad.Sci.USA, 111, 2014
7UQU	Crystal Structure of Mouse Cadherin-23 EC9 分子名称: CALCIUM ION, Cadherin-23 著者 Sandhu, J.S, De La Torre, P, Sotomayor, M. 登録日 2022-04-20 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.976 Å) 主引用文献 Crystal Structure of Mouse Cadherin-23 EC9 To be published
2EE0	Solution structures of the CA domain of human protocadherin 9 分子名称: Protocadherin-9 著者 Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-15 公開日 2007-08-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structures of the CA domain of human protocadherin 9 To be Published
1L3W	C-cadherin Ectodomain 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Boggon, T.J, Murray, J, Chappuis-Flament, S, Wong, E, Gumbiner, B.M, Shapiro, L. 登録日 2002-03-01 公開日 2002-04-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 C-cadherin ectodomain structure and implications for cell adhesion mechanisms Science, 296, 2002
1SUH	AMINO-TERMINAL DOMAIN OF EPITHELIAL CADHERIN IN THE CALCIUM BOUND STATE, NMR, 20 STRUCTURES 分子名称: EPITHELIAL CADHERIN 著者 Overduin, M, Tong, K.I, Kay, C.M, Ikura, M. 登録日 1996-01-30 公開日 1996-07-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 1H, 15N and 13C resonance assignments and monomeric structure of the amino-terminal extracellular domain of epithelial cadherin. J.Biomol.NMR, 7, 1996
2YST	Solution structure of the third cadherin domain from human protocadherin 7 分子名称: Protocadherin-7 著者 Seimiya, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-03 公開日 2007-10-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the third cadherin domain from human protocadherin 7 To be Published
1EDH	E-CADHERIN DOMAINS 1 AND 2 IN COMPLEX WITH CALCIUM 分子名称: CALCIUM ION, E-CADHERIN, MERCURY (II) ION 著者 Nagar, B, Overduin, M, Ikura, M, Rini, J.M. 登録日 1996-05-15 公開日 1997-01-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature, 380, 1996
4XHZ	Crystal Structure of Human Protocadherin-15 EC8-10 分子名称: CALCIUM ION, CHLORIDE ION, Protocadherin-15 著者 Araya-Secchi, R, Sotomayor, M. 登録日 2015-01-06 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 An elastic element in the protocadherin-15 tip link of the inner ear. Nat Commun, 7, 2016
5J5J	Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Brasch, J, Harrison, O.J, Shapiro, L. 登録日 2016-04-02 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 Structural basis of adhesive binding by desmocollins and desmogleins. Proc.Natl.Acad.Sci.USA, 113, 2016
7SKH	Crystal Structure of Mouse Cadherin-23 EC16-17 分子名称: CALCIUM ION, Cadherin-23 著者 Sudar, J.C, Sandhu, J.S, Sotomayor, M. 登録日 2021-10-20 公開日 2022-10-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.265 Å) 主引用文献 Crystal Structure of Mouse Cadherin-23 EC16-17 to be published
7STZ	Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-11-15 公開日 2022-01-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1, 2022
7N86	Crystal Structure of Human Protocadherin-24 EC1-2 Form II 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Modak, D, Gray, M.E, Sotomayor, M. 登録日 2021-06-13 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.175 Å) 主引用文献 Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent. Plos Biol., 19, 2021
5I8D	Crystal Structure of Mouse Cadherin-23 EC19-21 S2064P 分子名称: CALCIUM ION, Cadherin-23 著者 Jaiganesh, A, Sotomayor, M. 登録日 2016-02-18 公開日 2017-08-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 2018
7N4P	Crystal Structure of Lizard Cadherin-23 EC1-2 分子名称: CALCIUM ION, Cadherin 23, SODIUM ION 著者 Nisler, C.R, Sotomayor, M. 登録日 2021-06-04 公開日 2022-06-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation. Mol.Biol.Evol., 40, 2023
5IRY	Crystal structure of human Desmocollin-1 ectodomain 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Brasch, J, Harrison, O.J, Shapiro, L. 登録日 2016-03-15 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.095 Å) 主引用文献 Structural basis of adhesive binding by desmocollins and desmogleins. Proc.Natl.Acad.Sci.USA, 113, 2016
5JYM	Human P-cadherin EC12 with scFv TSP11 bound 分子名称: Antibody scFv TSP11, CALCIUM ION, Cadherin-3 著者 Caaveiro, J.M.M, Kudo, S, Tsumoto, K. 登録日 2016-05-14 公開日 2016-12-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin Sci Rep, 7, 2017
5JYL	Human P-cadherin MEC1 with scFv TSP7 bound 分子名称: CHLORIDE ION, Cadherin-3, GLYCEROL, ... 著者 Caaveiro, J.M.M, Kudo, S, Tsumoto, K. 登録日 2016-05-14 公開日 2016-12-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin Sci Rep, 7, 2017
7CMF	Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) 分子名称: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3 著者 Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. 登録日 2020-07-27 公開日 2021-09-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
7CME	Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor) 分子名称: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... 著者 Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. 登録日 2020-07-27 公開日 2021-09-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion Commun Biol, 4, 2021
7CYM	Crystal structure of LI-Cadherin EC1-4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Caaveiro, J.M.M, Yui, A, Tsumoto, K. 登録日 2020-09-03 公開日 2021-08-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of dimerization and structural features of human LI-cadherin. J.Biol.Chem., 297, 2021
8D40	Crystal structure of human CELSR1 EC1-4 分子名称: CALCIUM ION, Cadherin EGF LAG seven-pass G-type receptor 1, SODIUM ION 著者 Tamilselvan, E, Sotomayor, M. 登録日 2022-06-01 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.554 Å) 主引用文献 Crystal structure of human CELSR1 EC1-4 to be published

 

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