PDB: 278 件ウェブページステータス検索Chemie searchBIRD

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5OOW	Crystal structure of lobe II from the nucleotide binding domain of DnaK in complex with AMPPCP 分子名称: Chaperone protein DnaK, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Jakob, R.P, Bauer, D, Meinhold, S, Stigler, J, Merkel, U, Maier, T, Rief, M, Zoldak, G. 登録日 2017-08-09 公開日 2018-04-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ZHI	Structure of the Plasmodium falciparum Hsp70-x substrate binding domain in complex with hydrophobic peptide 分子名称: ASN-ARG-LEU-LEU-LEU-THR-GLY, Heat shock protein 70 著者 Schmidt, J, Vakonakis, I. 登録日 2020-06-23 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure of the PfHsp70-x SBD Acta Crystallographica Section F
6NHK	Mortalin nucleotide binding domain in the ADP-bound state 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Page, R.C, Moseng, M.A, Nix, J.C. 登録日 2018-12-23 公開日 2019-04-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.777 Å) 主引用文献 Biophysical Consequences of EVEN-PLUS Syndrome Mutations for the Function of Mortalin. J.Phys.Chem.B, 123, 2019
1HJO	ATPase domain of human heat shock 70kDa protein 1 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... 著者 Osipiuk, J, Walsh, M.A, Freeman, B.C, Morimoto, R.I, Joachimiak, A. 登録日 1998-10-13 公開日 1998-10-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a new crystal form of human Hsp70 ATPase domain. Acta Crystallogr.,Sect.D, 55, 1999
2KHO	NMR-RDC / XRAY structure of E. coli HSP70 (DNAK) chaperone (1-605) complexed with ADP and substrate 分子名称: Heat shock protein 70 著者 Zuiderweg, E.R.P, Bertelsen, E.B. 登録日 2009-04-10 公開日 2009-05-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate. Proc.Natl.Acad.Sci.USA, 106, 2009
6P2U	Structure of Mortalin-NBD with N6-propargyladenosine-5'-diphosphate 分子名称: 9-{5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-alpha-D-ribofuranosyl}-N-(prop-2-yn-1-yl)-9H-purin-6-amine, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Moseng, M.A, Page, R.C. 登録日 2019-05-22 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin. Febs Lett., 593, 2019
5TKY	Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein 著者 Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I. 登録日 2016-10-10 公開日 2016-11-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun, 7, 2016
7PLK	Crystal structure bovine Hsc70(aa1-554)E213A/D214A in complex with nicotinic-acid-derivative 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-pyrrol-1-ylpyridine-3-carboxylic acid, GLYCEROL, ... 著者 Zehe, M, Grimm, C, Sotriffer, C. 登録日 2021-08-31 公開日 2022-09-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.48781371 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
3KVG	Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP 分子名称: 1,2-ETHANEDIOL, Heat shock 70 (HSP70) protein, PHOSPHATE ION, ... 著者 Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) 登録日 2009-11-30 公開日 2010-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of the N-terminal domain of Hsp70 (cgd2_20) from Cryptosporidium parvum in complex with AMPPNP To be Published
5XI9	Solution structure for human HSP70 substrate binding domain 分子名称: Heat shock 70 kDa protein 1A 著者 Hoshikawa, M, Tochio, N, Tate, S. 登録日 2017-04-26 公開日 2018-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Substrate Binding Switches the Conformation at the Lynchpin Site in the Substrate-Binding Domain of Human Hsp70 to Enable Allosteric Interdomain Communication. Molecules, 23, 2018
3L4I	CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM Cryptosporidium PARVUM IN COMPLEX WITH ADP and inorganic phosphate 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Pizarro, J.C, Wernimont, A.K, Hutchinson, A, Sullivan, H, Lew, J, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) 登録日 2009-12-20 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HSP70 (CGD2_20) FROM Cryptosporidium PARVUM IN COMPLEX WITH ADP and inorganic phosphate To be Published
5XIR	Solution structure for human HSP70 substrate binding domain L542Y mutant 分子名称: Heat shock 70 kDa protein 1A 著者 Hoshikawa, M, Tochio, N, Tate, S. 登録日 2017-04-27 公開日 2018-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Substrate Binding Switches the Conformation at the Lynchpin Site in the Substrate-Binding Domain of Human Hsp70 to Enable Allosteric Interdomain Communication. Molecules, 23, 2018
1U00	HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC 分子名称: Chaperone protein hscA, IscU recognition peptide 著者 Cupp-Vickery, J.R, Peterson, J.C, Ta, D.T, Vickery, L.E. 登録日 2004-07-12 公開日 2004-10-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of the Molecular Chaperone HscA Substrate Binding Domain Complexed with the IscU Recognition Peptide ELPPVKIHC. J.Mol.Biol., 342, 2004
6PMT	Structure of Mortalin-NBD with adenosine-5'-monophosphate and thiodiphosphate 分子名称: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Stress-70 protein, ... 著者 Moseng, M.A, Nix, J.C, Page, R.C. 登録日 2019-07-02 公開日 2020-07-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the mortalin nucleotide binding domain in complex with adenosine monophosphate to be published
2V7Y	Crystal structure of the molecular chaperone DnaK from Geobacillus kaustophilus HTA426 in post-ATP hydrolysis state 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHAPERONE PROTEIN DNAK, MAGNESIUM ION, ... 著者 Chang, Y.-W, Sun, Y.-J, Wang, C, Hsiao, C.-D. 登録日 2007-08-02 公開日 2008-04-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Crystal Structures of the 70-kDa Heat Shock Proteins in Domain Disjoining Conformation. J.Biol.Chem., 283, 2008
7RAX	ATP-binding state of the nucleotide-binding domain of Hsp70 DnaK mutant T199A 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... 著者 Wang, W, Hendrickson, W.A. 登録日 2021-07-04 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Visualization of Hsp70-catalyzed ATP Hydrolysis To Be Published
1YUW	crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant 分子名称: Heat shock cognate 71 kDa protein 著者 Jiang, J, Lafer, E.M, Prasad, K, Sousa, R. 登録日 2005-02-14 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of interdomain communication in the Hsc70 chaperone Mol.Cell, 20, 2005
2V7Z	Crystal structure of the 70-kDa heat shock cognate protein from Rattus norvegicus in post-ATP hydrolysis state 分子名称: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK COGNATE 71 KDA PROTEIN, PHOSPHATE ION 著者 Chang, Y.-W, Sun, Y.-J, Wang, C, Hsiao, C.-D. 登録日 2007-08-02 公開日 2008-04-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal Structures of the 70-kDa Heat Shock Proteins in Domain Disjoining Conformation. J.Biol.Chem., 283, 2008
5UMB	Crystal structure of ATPase domain of Malaria GRP78 with ADP bound 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone DnaK, MAGNESIUM ION, ... 著者 Chen, Y, Antoshchenko, T, Pizarro, J.C, Song, J.H, Park, H. 登録日 2017-01-26 公開日 2022-07-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Repurposing drugs to target the malaria parasite unfolding protein response. Sci Rep, 8, 2018
4B9Q	Open conformation of ATP-bound Hsp70 homolog DnaK 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHAPERONE PROTEIN DNAK, MAGNESIUM ION 著者 Kopp, J, Mayer, M.P, Sinning, I. 登録日 2012-09-06 公開日 2012-11-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones Mol.Cell, 48, 2012
1S3X	The crystal structure of the human Hsp70 ATPase domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70 kDa protein 1, ... 著者 Sriram, M, Osipiuk, J, Freeman, B, Morimoto, R.I, Joachimiak, A. 登録日 2004-01-14 公開日 2004-01-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain Structure, 5, 1997
2QWQ	Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP hydrolyzed form 分子名称: ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. 登録日 2007-08-10 公開日 2007-12-18 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
2QWL	Crystal structure of bovine hsc70 (1-394aa)in the ADP state 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. 登録日 2007-08-10 公開日 2007-12-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
6HAB	Crystal structure of BiP V461F (apo) 分子名称: DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP 著者 Yan, Y, Ron, D. 登録日 2018-08-07 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP. Nat Commun, 10, 2019
6RZQ	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain - ANP-PnP bound state 分子名称: GLYCEROL, Heat shock protein 70, MAGNESIUM ION, ... 著者 Vakonakis, I, Day, J. 登録日 2019-06-13 公開日 2019-10-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 ThePlasmodium falciparumHsp70-x chaperone assists the heat stress response of the malaria parasite. Faseb J., 33, 2019

 

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