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2AZE
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BU of 2aze by Molmil
Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
分子名称: Retinoblastoma-associated protein, Transcription factor Dp-1, Transcription factor E2F1
著者Rubin, S.M, Gall, A.L, Zheng, N, Pavletich, N.P.
登録日2005-09-10
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
Cell(Cambridge,Mass.), 123, 2005
6G0P
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BU of 6g0p by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated E2F1 peptide (K117ac/K120ac)
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, Transcription factor E2F1
著者Filippakopoulos, P, Picaud, S, Krojer, T, Sorrell, F, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C.
登録日2018-03-19
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Mol. Cell, 73, 2019
6ULS
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BU of 6uls by Molmil
BRD4-BD1 in complex with the a diacetylated-E2F1 peptide
分子名称: Bromodomain-containing protein 4, Diacetylated E2F1 Peptide (K117ac and K120ac)
著者Patel, K, Low, J.K.K, Mackay, J.P.
登録日2019-10-08
公開日2020-08-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism.
Biochemistry, 60, 2021
1H24
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BU of 1h24 by Molmil
CDK2/CyclinA in complex with a 9 residue recruitment peptide from E2F
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, TRANSCRIPTION FACTOR E2F1
著者Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
登録日2002-07-31
公開日2003-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1O9K
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BU of 1o9k by Molmil
Crystal structure of the retinoblastoma tumour suppressor protein bound to E2F peptide
分子名称: RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
著者Xiao, B, Spencer, J, Clements, A, Ali-Khan, N, Mittnacht, S, Broceno, C, Burghammer, M, Perrakis, A, Marmorstein, R, Gamblin, S.J.
登録日2002-12-16
公開日2003-03-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
5GOW
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BU of 5gow by Molmil
Solution structure of the complex between DP1 acidic region and TFIIH p62 PH domain
分子名称: DP1, General transcription factor IIH subunit 1
著者Okuda, M, Nishimura, Y.
登録日2016-07-29
公開日2016-12-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH
J. Mol. Biol., 428, 2016
4V8P
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BU of 4v8p by Molmil
T.thermophila 60S ribosomal subunit in complex with initiation factor 6.
分子名称: 26S RRNA, 5.8S RRNA, 5S RRNA, ...
著者Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N.
登録日2011-09-14
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6.
Science, 334, 2011
1H27
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BU of 1h27 by Molmil
CDK2/CyclinA in complex with an 11-residue recruitment peptide from p27
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, CYCLIN-DEPENDENT KINASE INHIBITOR 1B
著者Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
登録日2002-07-31
公開日2003-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1H25
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BU of 1h25 by Molmil
CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-ASSOCIATED PROTEIN
著者Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
登録日2002-07-31
公開日2003-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1H26
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BU of 1h26 by Molmil
CDK2/CyclinA in complex with an 11-residue recruitment peptide from p53
分子名称: CELL DIVISION PROTEIN KINASE 2, CELLULAR TUMOR ANTIGEN P53, CYCLIN A2
著者Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
登録日2002-07-31
公開日2003-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
1H28
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BU of 1h28 by Molmil
CDK2/CyclinA in complex with an 11-residue recruitment peptide from p107
分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-LIKE PROTEIN 1
著者Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N.
登録日2002-07-31
公開日2003-02-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A
Biochemistry, 41, 2002
7TOA
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BU of 7toa by Molmil
BRD3-BD1 in complex with RaPID linear peptide 3xAcK.1 (triAcK.1)
分子名称: 3xAcK.1 (triAcK.1), Bromodomain-containing protein 3, GLYCEROL
著者Patel, K, Low, J.K.K, Mackay, J.P.
登録日2022-01-23
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome.
J.Biol.Chem., 299, 2023
3JVE
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BU of 3jve by Molmil
Crystal Structure of the Sixth BRCT Domain of TopBP1
分子名称: DNA topoisomerase 2-binding protein 1
著者Leung, C.C, Kellogg, E, Baker, D, Glover, J.N.M.
登録日2009-09-16
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1.
Protein Sci., 19, 2010
5UFL
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BU of 5ufl by Molmil
Crystal structure of a CIP2A core domain
分子名称: Protein CIP2A, ZINC ION
著者Wang, Z, Wang, J, Rao, Z, Xu, W.
登録日2017-01-04
公開日2017-02-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56.
EMBO Rep., 18, 2017

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件を2024-05-29に公開中

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