8QXJ
 
 | | Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | | 著者 | Acton, O.J, Sheppard, D, Rosenthal, P.B, Taylor, I.A. | | 登録日 | 2023-10-24 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis.
Nat Commun, 15, 2024
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7LAN
 | | CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH COMPOUND-30 AKA 7-[(3~{S},4~{R},6~{R})-4-benzyl-2-oxa-7,13,14-triazatetracyclo[14.3.1.1^{3,6}.1^{11,14}]docosa-1(19),11(21),12,16(20),17-pentaen-10-yl]-3~{H}-triazolo[4,5-b]pyridin-5-amine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(3R,4S,6S,10R)-4-benzyl-2-oxa-7,13,14-triazatetracyclo[14.3.1.1~3,6~.1~11,14~]docosa-1(20),11(21),12,16,18-pentaen-10-yl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine, ... | | 著者 | Khan, J.A. | | 登録日 | 2021-01-06 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO).
Bioorg.Med.Chem.Lett., 42, 2021
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8RIT
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8RAJ
 | | NMR structure of PKS docking domains | | 分子名称: | Beta-ketoacyl synthase, Trimethylamine monooxygenase | | 著者 | Scat, S, Weissman, K.J, Chagot, B. | | 登録日 | 2023-12-01 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-07-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into docking in megasynthases from the investigation of the toblerol trans -AT polyketide synthase: many alpha-helical means to an end.
Rsc Chem Biol, 5, 2024
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1C97
 | | S642A:ISOCITRATE COMPLEX OF ACONITASE | | 分子名称: | IRON/SULFUR CLUSTER, ISOCITRIC ACID, MITOCHONDRIAL ACONITASE, ... | | 著者 | Lloyd, S.J, Lauble, H, Prasad, G.S, Stout, C.D. | | 登録日 | 1999-07-31 | | 公開日 | 1999-08-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | The mechanism of aconitase: 1.8 A resolution crystal structure of the S642a:citrate complex.
Protein Sci., 8, 1999
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4GTY
 | | Crystal structure of mouse Enpp1 in complex with GMP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Kato, K, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2012-08-29 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7LAL
 | | CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH COMPOUND-18 AKA 7-(3-(2,3-DIHYDRO-1H-INDEN-1-YLAMINO)-1-PHENYLPROPYL)-1H-[1,2,3]TRIAZOLO[4,5-B]PYRIDIN-5-AMINE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(1R)-3-{[(1R)-2,3-dihydro-1H-inden-1-yl]amino}-1-phenylpropyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine, ... | | 著者 | Khan, J.A. | | 登録日 | 2021-01-06 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO).
Bioorg.Med.Chem.Lett., 42, 2021
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8QHS
 | | Cryo-EM structure of the monocin tail-tube, MttP. | | 分子名称: | Antigen A | | 著者 | Nadejda, S, Lichtenstein, R, Schlussel, S, Azulay, G, Borovok, I, Holdengraber, V, Elad, N, Wolf, S.G, Zalk, R, Zarivach, R, Frank, G.A, Herskovits, A.A. | | 登録日 | 2023-09-10 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Tailocin cell factories
To Be Published
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8QUV
 | | Crystal structure of chlorite dismutase at 3000 eV with no absorption corrections | | 分子名称: | CHLORIDE ION, Chlorite Dismutase, GLYCEROL, ... | | 著者 | Duman, R, Wagner, A, Kamps, J, Orville, A. | | 登録日 | 2023-10-17 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions.
J.Appl.Crystallogr., 57, 2024
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8QOQ
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8QVS
 | | Crystal structure of Ompk36 GD at 3500 eV based on a combination of spherical harmonics and analytical absorption corrections | | 分子名称: | OmpK36, SULFATE ION | | 著者 | Duman, R, Wagner, A, Beis, K, Wong, J. | | 登録日 | 2023-10-18 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions.
J.Appl.Crystallogr., 57, 2024
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8QWO
 | | Structure of p53 cancer mutant Y234C | | 分子名称: | Cellular tumor antigen p53, GLYCEROL, ZINC ION | | 著者 | Balourdas, D.I, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | | 登録日 | 2023-10-19 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
Cell Death Dis, 15, 2024
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8RBM
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1C8C
 | | CRYSTAL STRUCTURES OF THE CHROMOSOMAL PROTEINS SSO7D/SAC7D BOUND TO DNA CONTAINING T-G MISMATCHED BASE PAIRS | | 分子名称: | 5'-D(*GP*TP*GP*AP*TP*CP*GP*C)-3', DNA-BINDING PROTEIN 7A | | 著者 | Su, S, Gao, Y.-G, Robinson, H, Liaw, Y.-C, Edmondson, S.P, Shriver, J.W, Wang, A.H.-J. | | 登録日 | 2000-05-04 | | 公開日 | 2001-05-04 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structures of the chromosomal proteins Sso7d/Sac7d bound to DNA containing T-G mismatched base-pairs.
J.Mol.Biol., 303, 2000
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8RA0
 | | Crystal structure of CysF | | 分子名称: | AMP-dependent synthetase, CITRATE ANION, TETRAETHYLENE GLYCOL | | 著者 | Levy, C.W. | | 登録日 | 2023-11-30 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Cryptic enzymatic assembly of peptides armed with beta-lactone warheads.
Nat.Chem.Biol., 2024
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8RF2
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 1E7 refined against the anomalous diffraction data | | 分子名称: | 1-benzothiophen-5-amine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8RPK
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8QWK
 | | Structure of p53 cancer mutant Y126C | | 分子名称: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, ZINC ION | | 著者 | Markl, A.M, Balourdas, D.I, Kraemer, A, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | | 登録日 | 2023-10-19 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
Cell Death Dis, 15, 2024
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8RB9
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8RFC
 | | Crystal structure of N-terminal SARS-CoV-2 nsp1 in complex with fragment hit 7H2_AL1 refined against the anomalous diffraction data | | 分子名称: | (1~{R})-1-(4-bromophenyl)ethanamine, Host translation inhibitor nsp1 | | 著者 | Ma, S, Damfo, S, Mykhaylyk, V, Kozielski, F. | | 登録日 | 2023-12-12 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | High-confidence placement of low-occupancy fragments into electron density using the anomalous signal of sulfur and halogen atoms.
Acta Crystallogr D Struct Biol, 80, 2024
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8QWP
 | | Structure of p53 cancer mutant Y236C | | 分子名称: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, L(+)-TARTARIC ACID, ... | | 著者 | Balourdas, D.I, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | | 登録日 | 2023-10-19 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
Cell Death Dis, 15, 2024
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1CDB
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8QOS
 | | Capra hircus reactive intermediate deaminase A - V25W | | 分子名称: | 1,2-ETHANEDIOL, 2-iminobutanoate/2-iminopropanoate deaminase, POTASSIUM ION | | 著者 | Rizzi, G, Visentin, C, Di Pisa, F, Ricagno, S. | | 登録日 | 2023-09-29 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Capra hircus reactive intermediate deaminase A - V25W
To Be Published
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8QK1
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8QRM
 | | mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3 | | 分子名称: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | | 著者 | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | | 登録日 | 2023-10-09 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Nat Commun, 15, 2024
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