PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

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4ZZ1	HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({4-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-2-CARBONYL}-AMINO)-PENTANEDIOIC ACID 分子名称: (S)-2-({4-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)-propyl]-thiophene-2-carbonyl}-amino)-pentanedioic acid, GLYCINAMIDE RIBONUCLEOTIDE, Trifunctional purine biosynthetic protein adenosine-3 著者 Deis, S.M, Dann III, C.E. 登録日 2015-05-22 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.351 Å) 主引用文献 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors. J.Med.Chem., 58, 2015
2R84	Crystal structure of PurP from Pyrococcus furiosus complexed with AMP and AICAR 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... 著者 Zhang, Y, White, R.H, Ealick, S.E. 登録日 2007-09-10 公開日 2007-12-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii. Biochemistry, 47, 2008
2R7L	Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with ATP and AICAR 分子名称: 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, ADENOSINE-5'-TRIPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... 著者 Zhang, Y, White, R.H, Ealick, S.E. 登録日 2007-09-09 公開日 2007-12-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii. Biochemistry, 47, 2008
2FW9	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H59F from the acidophilic bacterium Acetobacter aceti, at pH 8 分子名称: N5-carboxyaminoimidazole ribonucleotide mutase, SULFATE ION 著者 Starks, C.M, Kappock, T.J. 登録日 2006-02-01 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
3C61	Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, AZIDE ION, CHLORIDE ION, ... 著者 Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2008-02-01 公開日 2008-02-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Dihydroorotate dehydrogenase from Leishmania donovani. To be Published
4L6H	Crystal structure of the Candida albicans Methionine Synthase in complex with Methotrexate and Homocysteine 分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHOTREXATE, ... 著者 Ubhi, D, Robertus, J.D. 登録日 2013-06-12 公開日 2014-03-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014
5BNT	X-ray Crystal Structure of a Aspartate-semialdehyde dehydrogenase bound to NADP from Pseudomonas aeruginosa 分子名称: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-05-26 公開日 2015-06-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray Crystal Structure of a Aspartate-semialdehyde dehydrogenase bound to NADP from Pseudomonas aeruginosa to be published
5BOR	Structure of Acetobacter aceti PurE-S57C, sulfonate form 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Sullivan, K.L, Kappock, T.J. 登録日 2015-05-27 公開日 2016-06-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Mutation of the conserved serine in two PurE classes To Be Published
2FWB	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H89F from the acidophilic bacterium Acetobacter aceti, at pH 8 分子名称: N5-carboxyaminoimidazole ribonucleotide mutase 著者 Starks, C.M, Kappock, T.J. 登録日 2006-02-01 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
2R7N	Crystal structure of FAICAR synthetase (PurP) from M. jannaschii complexed with ADP and FAICAR 分子名称: 5-(formylamino)-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxamide, 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Zhang, Y, White, R.H, Ealick, S.E. 登録日 2007-09-09 公開日 2007-12-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii. Biochemistry, 47, 2008
2R87	Crystal structure of PurP from Pyrococcus furiosus complexed with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, PurP protein PF1517 著者 Zhang, Y, White, R.H, Ealick, S.E. 登録日 2007-09-10 公開日 2007-12-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii. Biochemistry, 47, 2008
3BQ5	Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic) 分子名称: 1,2-ETHANEDIOL, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase, ... 著者 Pejchal, R, Smith, J.L, Ludwig, M.L. 登録日 2007-12-19 公開日 2008-03-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Metal active site elasticity linked to activation of homocysteine in methionine synthases. Proc.Natl.Acad.Sci.Usa, 105, 2008
4L5Z	Crystal structure of the Candida albicans Methionine Synthase in complex with Homocysteine 分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ZINC ION 著者 Ubhi, D, Robertus, J.D. 登録日 2013-06-11 公開日 2014-03-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014
4L65	Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate and Methionine 分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, ... 著者 Ubhi, D, Robertus, J.D. 登録日 2013-06-12 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014
4L78	Xenon Trapping and Statistical Coupling Analysis Uncover Regions Important for Structure and Function of Multidomain Protein StPurL 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. 登録日 2013-06-13 公開日 2013-12-11 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
2FWJ	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic bacterium Acetobacter aceti, complexed with AIR (5-aminoimidazole ribonucleotide) 分子名称: 5-AMINOIMIDAZOLE RIBONUCLEOTIDE, N5-carboxyaminoimidazole ribonucleotide mutase 著者 Starks, C.M, Kappock, T.J. 登録日 2006-02-02 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
4Z7J	Structure of Acetobacter aceti PurE-S57A 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 5-O-phosphono-beta-D-ribofuranose, ... 著者 Kappock, T.J, Sullivan, K.L. 登録日 2015-04-07 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 Mutation of the conserved serine in two PurE classes To Be Published
4ZZ2	HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({5-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-3-CARBONYL}-AMINO)-PENTANEDIOIC ACID 分子名称: (S)-2-({5-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)-propyl]-thiophene-3-carbonyl}-amino)-pentanedioic acid, GLYCINAMIDE RIBONUCLEOTIDE, Trifunctional purine biosynthetic protein adenosine-3 著者 Deis, S.M, Dann III, C.E. 登録日 2015-05-22 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors. J.Med.Chem., 58, 2015
2FW1	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic bacterium Acetobacter aceti, at pH 8.5 分子名称: ACETIC ACID, N5-carboxyaminoimidazole ribonucleotide mutase 著者 Starks, C.M, Kappock, T.J. 登録日 2006-01-31 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
2FW7	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H59N from the acidophilic bacterium Acetobacter aceti, at pH 8 分子名称: N5-carboxyaminoimidazole ribonucleotide mutase 著者 Starks, C.M, Kappock, T.J. 登録日 2006-02-01 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
2FWI	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H59D, from the acidophilic bacterium Acetobacter aceti, complexed with 5-aminoimidazole ribonucleotide (AIR) 分子名称: 5-AMINOIMIDAZOLE RIBONUCLEOTIDE, N5-carboxyaminoimidazole ribonucleotide mutase 著者 Starks, C.M, Kappock, T.J. 登録日 2006-02-02 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
2FW8	Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H89G from the acidophilic bacterium Acetobacter aceti, at pH 8 分子名称: N5-carboxyaminoimidazole ribonucleotide mutase 著者 Starks, C.M, Kappock, T.J. 登録日 2006-02-01 公開日 2006-06-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Biochemical and Structural Studies of N(5)-Carboxyaminoimidazole Ribonucleotide Mutase from the Acidophilic Bacterium Acetobacter aceti. Biochemistry, 45, 2006
7JLQ	cryo-EM structure of human ATG9A in LMNG micelles 分子名称: Autophagy-related protein 9A 著者 Maeda, S, Otomo, T. 登録日 2020-07-30 公開日 2020-10-28 最終更新日 2020-12-16 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure, lipid scrambling activity and role in autophagosome formation of ATG9A. Nat.Struct.Mol.Biol., 27, 2020
5AVM	Crystal structures of 5-aminoimidazole ribonucleotide (AIR) synthetase, PurM, from Thermus thermophilus 分子名称: Phosphoribosylformylglycinamidine cyclo-ligase, SULFATE ION 著者 Kanagawa, M, Baba, S, Watanabe, Y, Nakagawa, N, Ebihara, A, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2015-06-23 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures and ligand binding of PurM proteins from Thermus thermophilus and Geobacillus kaustophilus J.Biochem., 159, 2016
2FDS	Crystal Structure of Plasmodium Berghei Orotidine 5'-monophosphate Decarboxylase (ortholog of Plasmodium falciparum PF10_0225) 分子名称: IODIDE ION, orotidine-monophosphate-decarboxylase 著者 Qiu, W, Dong, A, Wasney, G, Vedadi, M, Lew, J, Kozieradski, I, Alam, Z, Melone, M, Weigelt, J, Sundstrom, M, Edwards, A, Arrowsmith, C, Hui, R, Gao, M, Bochkarev, A, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2005-12-14 公開日 2005-12-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007

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