4L5Z

Crystal structure of the Candida albicans Methionine Synthase in complex with Homocysteine

Summary for 4L5Z

Entry DOI	10.2210/pdb4l5z/pdb
Related	4L61 4L64 4L65 4L6H 4L6O
Descriptor	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ZINC ION, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... (4 entities in total)
Functional Keywords	cobalamin-independent, surface entropy reduction, fungal, dual tim barrels, methionine synthase, transferase
Biological source	Candida albicans SC5314
Total number of polymer chains	1
Total formula weight	88389.55
Authors	Ubhi, D.,Robertus, J.D. (deposition date: 2013-06-11, release date: 2014-03-05, Last modification date: 2024-04-03)
Primary citation	Ubhi, D.,Kago, G.,Monzingo, A.F.,Robertus, J.D. Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426:1839-1847, 2014 Cited by PubMed: 24524835 DOI: 10.1016/j.jmb.2014.02.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.18 Å)

Structure validation