PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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5A7W	Crystal structure of human JMJD2A in complex with compound 35 分子名称: 1,2-ETHANEDIOL, 2-[5-[(4-hydroxyphenyl)carbonylamino]-2-oxidanyl-phenyl]pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, ... 著者 Nowak, R, Velupillai, S, Krojer, T, Gileadi, C, Johansson, C, Korczynska, M, Le, D.D, Younger, N, Gregori-Puigjane, E, Tumber, A, Iwasa, E, Pollock, S.B, Ortiz Torres, I, Kopec, J, Tallant, C, Froese, S, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Shoichet, B.K, Fujimori, D.G, Oppermann, U. 登録日 2015-07-10 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Docking and Linking of Fragments to Discover Jumonji Histone Demethylase Inhibitors. J.Med.Chem., 59, 2016
2Z2T	Crystal structure of the complex between gp41 fragment N36 and fusion inhibitor SC34EK 分子名称: ACETIC ACID, Fusion inhibitor peptide SC34EK, SULFATE ION, ... 著者 Nakamura, S, Ohkubo, T, Kobayashi, Y. 登録日 2007-05-28 公開日 2008-06-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Intrahelical Salt-bridges in a-Helical Peptide Enhances its Binding to the Target: A New Design for HIV-1 Fusion Inhibitors To be Published
7OCK	MAT in complex with SAMH 分子名称: S-adenosylmethionine synthase, SAM hydrolase 著者 Simon, H, Kleiner, D, Shmulevich, F, Zarivach, R, Zalk, R, Tang, H, Ding, F, Bershtein, S. 登録日 2021-04-27 公開日 2021-07-21 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 SAMase of Bacteriophage T3 Inactivates Escherichia coli's Methionine S -Adenosyltransferase by Forming Heteropolymers. Mbio, 12, 2021
4OE1	Crystal structure of the pentatricopeptide repeat protein PPR10 (C256S/C430S/C449S) in complex with an 18-nt PSAJ rna element 分子名称: Chloroplast pentatricopeptide repeat protein 10, PHOSPHATE ION, psaJ RNA 著者 Li, Q, Yan, C, Wu, J, Yin, P, Yan, N. 登録日 2014-01-11 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10). J.Biol.Chem., 289, 2014
2M4V	Mycobacterium tuberculosis RNA polymerase binding protein A (RbpA) and its interactions with sigma factors 分子名称: Putative uncharacterized protein 著者 Bortoluzzi, A, Muskett, F.W, Waters, L.C, Addis, P.W, Rieck, B, Munder, T, Schleier, S, Forti, F, Ghisotti, D, Carr, M.D, O'Hare, H.M. 登録日 2013-02-11 公開日 2013-04-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors. J.Biol.Chem., 288, 2013
3EI2	Structure of hsDDB1-drDDB2 bound to a 16 bp abasic site containing DNA-duplex 分子名称: 5'-D(*DAP*DAP*DAP*DTP*DGP*DAP*DAP*DTP*(3DR)P*DAP*DAP*DGP*DCP*DAP*DGP*DG)-3', 5'-D(*DCP*DCP*DTP*DGP*DCP*DTP*DTP*DTP*DAP*DTP*DTP*DCP*DAP*DTP*DTP*DT)-3', DNA damage-binding protein 1, ... 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
4WZN	CRYSTAL STRUCTURE OF THE 2B PROTEIN SOLUBLE DOMAIN FROM HEPATITIS A VIRUS 分子名称: GLYCEROL, Genome polyprotein 著者 Garriga, D, Vives-Adrian, L, Buxaderas, M, Ferreira-da-Silva, F, Almeida, B, Macedo-Ribeiro, S, Pereira, P.J, Verdaguer, N. 登録日 2014-11-20 公開日 2015-01-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Basis for Host Membrane Remodeling Induced by Protein 2B of Hepatitis A Virus. J.Virol., 89, 2015
4OLY	Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2014-01-25 公開日 2014-09-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
5ALJ	ligand complex structure of soluble epoxide hydrolase 分子名称: 2-(3-fluoro-4-methyl-anilino)-4-methyl-quinolin-5-ol, BIFUNCTIONAL EPOXIDE HYDROLASE 2, GLYCEROL, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
4OMG	Crystal structure of the bacterial diterpene cyclase COTB2 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Geranylgeranyl diphosphate cyclase, SODIUM ION 著者 Janke, R, Goerner, C, Hirte, M, Brueck, T, Loll, B. 登録日 2014-01-27 公開日 2014-06-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 The first structure of a bacterial diterpene cyclase: CotB2. Acta Crystallogr.,Sect.D, 70, 2014
2LYC	Structure of C-terminal domain of Ska1 分子名称: Spindle and kinetochore-associated protein 1 homolog 著者 Boeszoermenyi, A, Schmidt, J.C, Markus, M, Oberer, M, Cheeseman, I.M, Wagner, G, Arthanari, H. 登録日 2012-09-14 公開日 2012-10-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The kinetochore-bound ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments. Dev.Cell, 23, 2012
2VN5	The Clostridium cellulolyticum dockerin displays a dual binding mode for its cohesin partner 分子名称: CALCIUM ION, ENDOGLUCANASE A, SCAFFOLDING PROTEIN 著者 Pinheiro, B.A, Prates, J.A.M, Proctor, M.R, Gilbert, H.J, Davies, G.J, Money, V.A, Martinez-Fleites, C, Bayer, E.A, Fontes, C.M.G.A, Fierobe, H.P. 登録日 2008-01-31 公開日 2008-05-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Clostridium Cellulolyticum Dockerin Displays a Dual Binding Mode for its Cohesin Partner. J.Biol.Chem., 283, 2008
2CRX	STRUCTURE OF THE HOLLIDAY JUNCTION INTERMEDIATE IN CRE-LOXP SITE-SPECIFIC RECOMBINATION 分子名称: DNA 35-MER, PROTEIN (CRE RECOMBINASE) 著者 Gopaul, D.N, Guo, F, Vanduyne, G.D. 登録日 1998-06-19 公開日 1999-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination. EMBO J., 17, 1998
5AC6	S.enterica HisA mutant D10G, dup13-15, Q24L, G102A 分子名称: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SULFATE ION 著者 Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. 登録日 2015-08-12 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.993 Å) 主引用文献 The Protein Structures, Functions and Dynamics of Adaptive Evolution To be Published
4WYO	Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1 分子名称: 2'-tert-butyl-1-(2H-indazol-5-ylcarbonyl)-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazol]-7'(6'H)-one, Acetyl-CoA carboxylase 著者 Vajdos, F.F. 登録日 2014-11-17 公開日 2015-01-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. J.Med.Chem., 57, 2014
1P2D	Crystal Structure of Glycogen Phosphorylase B in complex with Beta Cyclodextrin 分子名称: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ... 著者 Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M. 登録日 2003-04-15 公開日 2003-09-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies. Protein Sci., 12, 2003
4OFY	Crystal Structure of the Complex of SYG-1 D1-D2 and SYG-2 D1-D4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL MERCURY ION, ... 著者 Ozkan, E, Garcia, K.C. 登録日 2014-01-15 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell(Cambridge,Mass.), 156, 2014
5DJS	Thermobaculum terrenum O-GlcNAc transferase mutant - K341M 分子名称: Tetratricopeptide TPR_2 repeat protein, URIDINE-5'-DIPHOSPHATE 著者 Ostrowski, A, Gundogdu, M, Ferenbach, A.T, Lebedev, A, van Aalten, D.M.F. 登録日 2015-09-02 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Evidence for a Functional O-Linked N-Acetylglucosamine (O-GlcNAc) System in the Thermophilic Bacterium Thermobaculum terrenum. J.Biol.Chem., 290, 2015
2Z2B	Deletion 107-116 mutant of dihydroorotase from E. coli 分子名称: Dihydroorotase, ZINC ION 著者 Lee, M, Maher, M.J, Guss, J.M. 登録日 2007-05-17 公開日 2007-10-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State Biochemistry, 46, 2007
6WAH	Crystal Structure of SmcR L139R from Vibrio vulnificus 分子名称: 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION 著者 Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. 登録日 2020-03-25 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences. Nucleic Acids Res., 49, 2021
5A5K	AtGSTF2 from Arabidopsis thaliana in complex with camalexin 分子名称: (2Z)-2-indol-3-ylidene-3H-1,3-thiazole, GLUTATHIONE S-TRANSFERASE F2 著者 Ahmad, L, Rylott, E, Bruce, N.C, Edwards, R, Grogan, G. 登録日 2015-06-18 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands. FEBS Open Bio, 7, 2017
4FSE	crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with N-(N-(4-amino-3,5- dichlorobenzyl)carbamimidoyl)-3-(4-methoxyphenyl)-5- methyl-4-isothiazolecarboxamide 分子名称: Beta-secretase 1, IODIDE ION, N-[N-(4-amino-3,5-dichlorobenzyl)carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide 著者 Muckelbauer, J.K. 登録日 2012-06-27 公開日 2012-10-10 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Acyl guanidine inhibitors of beta-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesis J.Med.Chem., 55, 2012
5X5B	Prefusion structure of SARS-CoV spike glycoprotein, conformation 2 分子名称: Spike glycoprotein 著者 Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. 登録日 2017-02-15 公開日 2017-05-03 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
4WZQ	Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA 分子名称: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ... 著者 Verdaguer, N, Ferrer-Orta, C. 登録日 2014-11-20 公開日 2015-05-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
6W0E	Open-gate KcsA soaked in 10 mM BaCl2 分子名称: BARIUM ION, Fab Heavy Chain, Fab Light Chain, ... 著者 Rohaim, A, Gong, L, Li, J. 登録日 2020-02-29 公開日 2020-07-08 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.512 Å) 主引用文献 Open and Closed Structures of a Barium-Blocked Potassium Channel. J.Mol.Biol., 432, 2020

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