6BKA
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![BU of 6bka by Molmil](/molmil-images/mine/6bka) | Crystal Structure of Nitronate Monooxygenase from Cyberlindnera saturnus | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Agniswamy, J, Fang, Y.-F, Weber, I.T. | 登録日 | 2017-11-08 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of yeast nitronate monooxygenase from Cyberlindnera saturnus. Proteins, 86, 2018
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6BL4
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![BU of 6bl4 by Molmil](/molmil-images/mine/6bl4) | Crystal Complex of Cyclooxygenase-2 with indomethacin-ethylenediamine-dansyl conjugate | 分子名称: | 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[2-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethyl]acetamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Xu, S, Uddin, M.J, Banerjee, S, Marnett, L.J. | 登録日 | 2017-11-09 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. J.Biol.Chem., 294, 2019
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6BMF
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![BU of 6bmf by Molmil](/molmil-images/mine/6bmf) | Vps4p-Vta1p complex with peptide binding to the central pore of Vps4p | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Han, H, Monroe, N, Shen, P, Sundquist, W.I, Hill, C.P. | 登録日 | 2017-11-14 | 公開日 | 2017-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets. Elife, 6, 2017
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5VIF
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![BU of 5vif by Molmil](/molmil-images/mine/5vif) | Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase | 分子名称: | 2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ... | 著者 | Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H. | 登録日 | 2017-04-15 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nat. Chem. Biol., 13, 2017
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6BNM
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![BU of 6bnm by Molmil](/molmil-images/mine/6bnm) | Crystal Structure of the P-Rex2 PH domain | 分子名称: | CHLORIDE ION, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein | 著者 | Cash, J.N, Sharma, P.V, Tesmer, J.J.G. | 登録日 | 2017-11-17 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP3. J.Struct.Biol., 1, 2019
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4WFX
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5VG0
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4X1X
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5VEY
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![BU of 5vey by Molmil](/molmil-images/mine/5vey) | Solution NMR structure of histone H2A-H2B mono-ubiquitylated at H2A Lys15 in complex with RNF169 (653-708) | 分子名称: | E3 ubiquitin-protein ligase RNF169, Histone H2B type 1-J,Histone H2A type 1-B/E, Polyubiquitin-B | 著者 | Hu, Q, Botuyan, M.V, Cui, G, Mer, G. | 登録日 | 2017-04-06 | 公開日 | 2017-05-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18. Mol. Cell, 66, 2017
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5VHX
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![BU of 5vhx by Molmil](/molmil-images/mine/5vhx) | GluA2-1xGSG1L bound to ZK | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Germ cell-specific gene 1-like protein, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | 登録日 | 2017-04-13 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes. Neuron, 94, 2017
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2PN8
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![BU of 2pn8 by Molmil](/molmil-images/mine/2pn8) | Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase) | 分子名称: | Peroxiredoxin-4 | 著者 | Pilka, E.S, Kavanagh, K.L, Cooper, C, von Delft, F, Sundstrom, M, Arrowsmith, C.A, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-04-24 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase). To be Published
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5VJH
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![BU of 5vjh by Molmil](/molmil-images/mine/5vjh) | Closed State CryoEM Reconstruction of Hsp104:ATPyS and FITC casein | 分子名称: | FITC casein, Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Gates, S.N, Yokom, A.L, Lin, J.-B, Jackrel, M.E, Rizo, A.N, Kendsersky, N.M, Buell, C.E, Sweeny, E.A, Chuang, E, Torrente, M.P, Mack, K.L, Su, M, Shorter, J, Southworth, D.R. | 登録日 | 2017-04-19 | 公開日 | 2017-07-05 | 最終更新日 | 2017-08-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science, 357, 2017
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4X7E
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4X7Q
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![BU of 4x7q by Molmil](/molmil-images/mine/4x7q) | PIM2 kinase in complex with Compound 1s | 分子名称: | 2-(2,6-difluorophenyl)-N-{4-[(3S)-pyrrolidin-3-yloxy]pyridin-3-yl}-1,3-thiazole-4-carboxamide, PHOSPHATE ION, Serine/threonine-protein kinase pim-2 | 著者 | Marcotte, D.J, Silvian, L.F. | 登録日 | 2014-12-09 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structure-based design of low-nanomolar PIM kinase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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4WNC
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6C4C
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![BU of 6c4c by Molmil](/molmil-images/mine/6c4c) | Crystal structure of 3-nitropropionate modified isocitrate lyase from Mycobacterium tuberculosis with glyoxylate and pyruvate | 分子名称: | 3-NITROPROPANOIC ACID, GLYOXYLIC ACID, Isocitrate lyase 1, ... | 著者 | Kreitler, D.F, Ray, S, Murkin, A.S, Gulick, A.M. | 登録日 | 2018-01-11 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition. ACS Chem. Biol., 13, 2018
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5VO2
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6C5Z
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![BU of 6c5z by Molmil](/molmil-images/mine/6c5z) | Human UDP-Glucose Dehydrogenase A225L substitutuion with UDP-glucose and NADH bound | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, UDP-glucose 6-dehydrogenase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | 著者 | Gross, P.G, Sidlo, A.M, Walsh, R.M, Peeples, W.B, Wood, Z.A. | 登録日 | 2018-01-17 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | The A225L Substitution of hUGDH alters structure and function To Be Published
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6C8C
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![BU of 6c8c by Molmil](/molmil-images/mine/6c8c) | Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06 | 分子名称: | 8-chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one, Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain | 著者 | Najeeb, J, Zhou, P. | 登録日 | 2018-01-24 | 公開日 | 2019-06-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy. Cell, 178, 2019
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2PMF
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![BU of 2pmf by Molmil](/molmil-images/mine/2pmf) | The crystal structure of a human glycyl-tRNA synthetase mutant | 分子名称: | CHLORIDE ION, GLYCEROL, Glycyl-tRNA synthetase | 著者 | Xie, W. | 登録日 | 2007-04-21 | 公開日 | 2007-05-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Long-range structural effects of a Charcot-Marie- Tooth disease-causing mutation in human glycyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 104, 2007
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6C9I
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![BU of 6c9i by Molmil](/molmil-images/mine/6c9i) | Single-Particle reconstruction of DARP14 - A designed protein scaffold displaying ~17kDa DARPin proteins - Scaffold | 分子名称: | DARP14 - Subunit A with DARPin, DARP14 - Subunit B | 著者 | Gonen, S, Liu, Y, Yeates, T.O, Gonen, T. | 登録日 | 2018-01-26 | 公開日 | 2018-03-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2PJV
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6C0M
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![BU of 6c0m by Molmil](/molmil-images/mine/6c0m) | The synthesis, biological evaluation and structural insights of unsaturated 3-N-substituted sialic acids as probes of human parainfluenza virus-3 haemagglutinin-neuraminidase | 分子名称: | 1,2-ETHANEDIOL, 2,6-anhydro-3,5-dideoxy-5-[(2-methylpropanoyl)amino]-3-(4-phenyl-1H-1,2,3-triazol-1-yl)-D-glycero-D-galacto-non-2-enoni c acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dirr, L, Ve, T, von Itzstein, M. | 登録日 | 2018-01-01 | 公開日 | 2018-06-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structural Insights into Human Parainfluenza Virus 3 Hemagglutinin-Neuraminidase Using Unsaturated 3- N-Substituted Sialic Acids as Probes. ACS Chem. Biol., 13, 2018
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2PME
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![BU of 2pme by Molmil](/molmil-images/mine/2pme) | The Apo crystal Structure of the glycyl-tRNA synthetase | 分子名称: | Glycyl-tRNA synthetase | 著者 | Xie, W. | 登録日 | 2007-04-21 | 公開日 | 2007-05-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Long-range structural effects of a Charcot-Marie- Tooth disease-causing mutation in human glycyl-tRNA synthetase. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2POZ
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