7OFH
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7SHX
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1SHJ
| Caspase-7 in complex with DICA allosteric inhibitor | 分子名称: | 2-(2,4-DICHLORO-PHENOXY)-N-(2-MERCAPTO-ETHYL)-ACETAMIDE, Caspase-7, SULFATE ION | 著者 | Hardy, J.A, Lam, J, Nguyen, J.T, O'Brien, T, Wells, J.A. | 登録日 | 2004-02-25 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of an allosteric site in the caspases Proc.Natl.Acad.Sci.USA, 101, 2004
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7SIJ
| Myocilin OLF mutant E352K | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-14 | 公開日 | 2023-01-11 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SJV
| Myocilin OLF mutant T353I | 分子名称: | CALCIUM ION, Myocilin, C-terminal fragment, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-19 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SKF
| Myocilin OLF mutant A445V | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-20 | 公開日 | 2023-01-11 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.282 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SJT
| Myocilin OLF mutant K398R | 分子名称: | CALCIUM ION, Myocilin, C-terminal fragment, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-19 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SKE
| Myocilin OLF mutant R296H | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-20 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SJU
| Myocilin OLF mutant T293K | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-19 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.391 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SIB
| Myocilin OLF mutant K500R | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-13 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SKD
| Myocilin OLF mutant S331L | 分子名称: | CALCIUM ION, Myocilin, C-terminal fragment, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-20 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.712 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SJW
| Myocilin OLF mutant L303I | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-19 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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7SKG
| Myocilin OLF mutant V329M | 分子名称: | CALCIUM ION, GLYCEROL, Myocilin, ... | 著者 | Scelsi, H.S, Barlow, B.M, Lieberman, R.L. | 登録日 | 2021-10-20 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability. Dis Model Mech, 16, 2023
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1SGF
| CRYSTAL STRUCTURE OF 7S NGF: A COMPLEX OF NERVE GROWTH FACTOR WITH FOUR BINDING PROTEINS (SERINE PROTEINASES) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NERVE GROWTH FACTOR, ... | 著者 | Bax, B.D.V, Blundell, T.L, Murray-Rust, J, Mcdonald, N.Q. | 登録日 | 1997-08-08 | 公開日 | 1998-05-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins. Structure, 5, 1997
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1SHL
| CASPASE-7 IN COMPLEX WITH FICA ALLOSTERIC INHIBITOR | 分子名称: | 5-FLUORO-1H-INDOLE-2-CARBOXYLIC ACID-(2-MERCAPTO-ETHYL)-AMIDE, Caspase-7 | 著者 | Hardy, J.A, Lam, J, Nguyen, J.T, O'Brien, T, Wells, J.A. | 登録日 | 2004-02-25 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery of an allosteric site in the caspases Proc.Natl.Acad.Sci.USA, 101, 2004
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6ATF
| HLA-DRB1*1402 in complex with Vimentin59-71 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scally, S.W, Ting, Y.T, Rossjohn, J. | 登録日 | 2017-08-29 | 公開日 | 2017-09-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Ann. Rheum. Dis., 76, 2017
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1SGT
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6ATZ
| HLA-DRB1*1402 in complex with citrullinated fibrinogen peptide | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta chain, ... | 著者 | Ting, Y.T, Scally, S.W, Rossjohn, J. | 登録日 | 2017-08-29 | 公開日 | 2017-09-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Ann. Rheum. Dis., 76, 2017
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6ATI
| HLA-DRB1*1402 in complex with Vimentin-64Cit59-71 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Scally, S.W, Ting, Y.T, Rossjohn, J. | 登録日 | 2017-08-29 | 公開日 | 2017-09-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Ann. Rheum. Dis., 76, 2017
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6B77
| Structures of the two-chain human plasma factor XIIa co-crystallized with potent inhibitors | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XII, GLYCEROL, ... | 著者 | Dementiev, A.A, Silva, A, Yee, C, Flavin, M.T, Partridge, J.R. | 登録日 | 2017-10-03 | 公開日 | 2018-03-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structures of human plasma beta-factor XIIa cocrystallized with potent inhibitors. Blood Adv, 2, 2018
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6B74
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7QOX
| Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | 著者 | Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J. | 登録日 | 2021-12-29 | 公開日 | 2023-01-18 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. J Thromb Haemost, 17, 2019
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7QOT
| Factor XI and Plasma Kallikrein apple domain structures reveals different kininogen bound complexes | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XIa heavy chain, Kininogen-1 light chain, ... | 著者 | Li, C, Awital, B, Wong, S, Dreveny, I, Meijers, J, Emsley, J. | 登録日 | 2021-12-28 | 公開日 | 2023-01-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | 主引用文献 | Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. J Thromb Haemost, 17, 2019
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4YFS
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6ZEQ
| Aspergillus oryzae Leucine Aminopeptidase A mature enzyme | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Watson, K.A, Baltulionis, G. | 登録日 | 2020-06-16 | 公開日 | 2021-06-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase. J.Struct.Biol., 213, 2021
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