PDB: 31171 件ウェブページステータス検索Chemie searchBIRD

---

8AQJ	Hydrophobic probe bound to Streptavidin - 2 分子名称: 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-[6-(dimethylamino)-1,3-bis(oxidanylidene)benzo[de]isoquinolin-2-yl]ethyl]pentanamide, Streptavidin 著者 Igareta, N.V, Ward, T.R. 登録日 2022-08-12 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Hydrophobic probe bound to Streptavidin - 2 To Be Published
7B55	Crystal structure of CaMKII-actinin complex bound to MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-actinin-2, Calcium/calmodulin-dependent protein kinase type II subunit alpha 著者 Zhu, J, Gold, M. 登録日 2020-12-03 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of CaMKII-actinin complex bound to MES To Be Published
7T5V	Structure of E. coli CapH C-terminal domain I99M mutant 分子名称: Helix-turn-helix domain-containing protein 著者 Lau, R.K, Corbett, K.D. 登録日 2021-12-13 公開日 2022-09-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage. Embo J., 41, 2022
7B56	Crystal structure of CaMKII-actinin complex bound to AMPPNP 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-actinin-2, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... 著者 Zhu, J, Gold, M. 登録日 2020-12-03 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of CaMKII-actinin complex bound to MES To Be Published
6Z3B	Low resolution structure of RgNanOx 分子名称: CITRIC ACID, Gfo/Idh/MocA family oxidoreductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Naismith, J.H, Lee, M. 登録日 2020-05-19 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria. J.Biol.Chem., 295, 2020
6GHY	Structure of Lytic Transglycosylase MltE inactive mutant E64Q from E.coli 分子名称: DI(HYDROXYETHYL)ETHER, Endo-type membrane-bound lytic murein transglycosylase A 著者 Batuecas, M.T, Hermoso, J.A. 登録日 2018-05-09 公開日 2018-10-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli. Biochemistry, 57, 2018
8UD0	Sterile Alpha Motif (SAM) domain from Tric1 from Arabidopsis thaliana - G241E mutant 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Chloroplastic import inner membrane translocase subunit HP30-1 著者 Olasz, B, Vrielink, A, Smithers, L. 登録日 2023-09-27 公開日 2024-05-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor. J.Biol.Chem., 300, 2024
7B57	Crystal structure of CaMKII-actinin complex bound to ADP 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Alpha-actinin-2, ... 著者 Zhu, J, Gold, M. 登録日 2020-12-03 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of CaMKII-actinin complex bound to ADP To Be Published
6OAW	Crystal structure of a CRISPR Cas-related protein 分子名称: UNKNOWN ATOM OR ION, WYL1 著者 Zhang, H, Dong, C, Li, L, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) 登録日 2019-03-18 公開日 2019-04-10 最終更新日 2019-06-12 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into the modulatory role of the accessory protein WYL1 in the Type VI-D CRISPR-Cas system. Nucleic Acids Res., 47, 2019
6C4W	Structure of the yeast Pichia membranifaciens cytochrome c 分子名称: HEME C, cytochrome c 著者 McPherson, A. 登録日 2018-01-13 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Characterization of two crystal forms of cytochrome c from Valida membranifaciens to be published
7T5T	Structure of Thauera sp. K11 CapP 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CapP toxin, SULFATE ION, ... 著者 Lau, R.K, Corbett, K.D. 登録日 2021-12-13 公開日 2022-09-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage. Embo J., 41, 2022
6ZDT	Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain 分子名称: Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin 著者 Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W. 登録日 2020-06-15 公開日 2021-02-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain. Rna, 27, 2021
6KEL	Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutathione S-transferase E14 著者 Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Senda, T, Niwa, R. 登録日 2019-07-04 公開日 2019-10-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
6GUK	CDK2 in complex with CGP74514A 分子名称: Cyclin-dependent kinase 2, ~{N}2-[(1~{R},2~{S})-2-azanylcyclohexyl]-~{N}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine 著者 Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. 登録日 2018-06-19 公開日 2018-12-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition. Cell Chem Biol, 26, 2019
6ZED	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX with compound F1 分子名称: 1,2-ETHANEDIOL, 4,5-dimethyl-1~{H}-pyrazolo[3,4-c]pyridazin-3-amine, Bromodomain-containing protein 4 著者 Krojer, T, Martinez-Cartro, M, Picaud, S, Filippakopoulos, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Barril, X, von Delft, F, Structural Genomics Consortium (SGC) 登録日 2020-06-16 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX with compound F1 To Be Published
8A8X	TRIM7 PRYSPRY in complex with a MNV1-NS3 peptide HDDFGLQ 分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS3 C term peptide 著者 Luptak, J. 登録日 2022-06-24 公開日 2022-07-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing. Viruses, 14, 2022
8AGK	Botulinum neurotoxin subtype A6 cell binding domain in complex with GD1a ganglioside 分子名称: 1,2-ETHANEDIOL, Bont/A1, DI(HYDROXYETHYL)ETHER, ... 著者 Gregory, K.S, Acharya, K.R, Liu, S.M, Newell, A.R, Mojanaga, O.O. 登録日 2022-07-20 公開日 2022-09-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structures of the Clostridium botulinum Neurotoxin A6 Cell Binding Domain Alone and in Complex with GD1a Reveal Significant Conformational Flexibility. Int J Mol Sci, 23, 2022
6Z4H	A4V mutant of human SOD1 bound with benzyl benzoisoselenazolone derivative 2 in P21 space group 分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... 著者 Amporndanai, K, Hasnain, S.S. 登録日 2020-05-25 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis. Ebiomedicine, 59, 2020
6ZEJ	Structure of PP1-Phactr1 chimera [PP1(7-304) + linker (SGSGS) + Phactr1(526-580)] 分子名称: 1,2-ETHANEDIOL, GLYCEROL, MANGANESE (II) ION, ... 著者 Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. 登録日 2020-06-16 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme. Elife, 9, 2020
8AHG	PAC-FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: Serine/threonine-protein kinase PAK 4, ~{N}-methyl-3-propan-2-yl-1~{H}-pyrazolo[3,4-c]pyridine-4-carboxamide 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.885 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
6C1A	MBD2 in complex with methylated DNA 分子名称: Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION, complement to dna strand 1, ... 著者 Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-01-04 公開日 2018-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
8AHH	PAC FragmentDEL: Photoactivated covalent capture of DNA encoded fragments for hit discovery 分子名称: 5-cyano-~{N}-methyl-pyrazolo[1,5-a]pyridine-3-carboxamide, Serine/threonine-protein kinase PAK 4 著者 Baker, L.M, Murray, J.B, Hubbard, R.E. 登録日 2022-07-21 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.037 Å) 主引用文献 PAC-FragmentDEL - photoactivated covalent capture of DNA-encoded fragments for hit discovery. Rsc Med Chem, 13, 2022
6Z4L	A4V mutant of human SOD1 bound with 2-(pyridin-3-ylmethyl)benzoisoselenazolone derivative 9 in P21 space group 分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... 著者 Amporndanai, K, Hasnain, S.S. 登録日 2020-05-25 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis. Ebiomedicine, 59, 2020
6OBR	PP1 Y134A in complex with Microcystin LR 分子名称: CHLORIDE ION, MANGANESE (II) ION, Microcystin LR, ... 著者 Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. 登録日 2019-03-21 公開日 2019-09-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
8AGF	Crystal structure of human Thiosulfate sulfurtransferase amino acids 2-297 分子名称: Thiosulfate sulfurtransferase 著者 Goor, H.v, Grove, M.R, AL-Dahmani, Z.m. 登録日 2022-07-19 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 The crystal structure of human Thiosulfate sulfurtransferase To Be Published

<953954955956957958959960961962963964965966967968>