PDB: 10962 件ウェブページステータス検索Chemie searchBIRD

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5X7V	Crystal structure of Nucleosome assembly protein S (PfNapS) from Plasmodium falciparum 分子名称: Nucleosome assembly protein 著者 Gill, J, Yogavel, M, Sharma, A. 登録日 2017-02-27 公開日 2017-03-15 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Structure, localization and histone binding properties of nuclear-associated nucleosome assembly protein from Plasmodium falciparum. Malar. J., 9, 2010
5XPA	Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 9'U10' on the target strand 分子名称: DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, RNA (5'-R(P*AP*UP*AP*CP*AP*AP*CP*CP*GP*UP*UP*CP*UP*AP*CP*UP*CP*CP*G)-3'), ... 著者 Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, J.D, Wang, Y. 登録日 2017-06-01 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Res., 45, 2017
5XPG	Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'U7' on the target strand 分子名称: 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*A P*GP*T)-3', 5'-R(*UP*AP*U*AP*CP*AP*AP*CP*CP*UP*AP*CP*AP*UP*AP*CP*CP*UP*CP* G)-3', MAGNESIUM ION, ... 著者 Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, J.D, Wang, Y. 登録日 2017-06-02 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Res., 45, 2017
5YAE	Ferulic acid esterase from Streptomyces cinnamoneus at 2.4 A resolution 分子名称: ACETATE ION, Esterase, SULFATE ION 著者 Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T. 登録日 2017-08-31 公開日 2017-12-06 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass. Appl. Environ. Microbiol., 84, 2018
2MBL	Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 分子名称: Top7 Fold Protein Top7m13 著者 Liu, G, Zanghellini, A.L, Chan, K, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2013-08-02 公開日 2013-11-13 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 To be Published
2MBM	Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 分子名称: Top7 Fold Protein Top7m13 著者 Liu, G, Zanghellini, A.L, Chan, K, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2013-08-02 公開日 2013-11-13 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 To be Published
5WFE	Cas1-Cas2-IHF-DNA holo-complex 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... 著者 Wright, A.V, Liu, J.J, Nogales, E, Doudna, J.A. 登録日 2017-07-11 公開日 2017-08-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structures of the CRISPR genome integration complex. Science, 357, 2017
5YGY	Crystal Structure of BACE1 in complex with (S)-N-(3-(2-amino-6-(fluoromethyl)-4 -methyl-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide 分子名称: Beta-secretase 1, GLYCEROL, IODIDE ION, ... 著者 Fuchino, K, Mitsuoka, Y, Masui, M, Kurose, N, Yoshida, S, Komano, K, Yamamoto, T, Ogawa, M, Unemura, C, Hosono, M, Ito, H, Sakaguchi, G, Ando, S, Ohnishi, S, Kido, Y, Fukushima, T, Miyajima, H, Hiroyama, S, Koyabu, K, Dhuyvetter, D, Borghys, H, Gijsen, H, Yamano, Y, Iso, Y, Kusakabe, K. 登録日 2017-09-27 公開日 2018-05-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Rational Design of Novel 1,3-Oxazine Based beta-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust A beta Reduction in the Brain J. Med. Chem., 61, 2018
5YRK	Crystal structure of PPL3C 分子名称: PPL3-b, SULFATE ION 著者 Nakae, S, Shionyu, M, Ogawa, T, Shirai, T. 登録日 2017-11-09 公開日 2018-08-29 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization Proteins, 86, 2018
5YP4	Crystal structure of dipeptidyl peptidase IV (DPP IV) with Lys-Pro from Pseudoxanthomonas mexicana WO24 分子名称: Dipeptidyl aminopeptidase 4, GLYCEROL, LYSINE, ... 著者 Roppongi, S, Suzuki, Y, Tateoka, C, Fuimoto, M, Morisawa, S, Iizuka, I, Nakamura, A, Honma, N, Shida, Y, Ogasawara, W, Tanaka, N, Sakamoto, Y, Nonaka, T. 登録日 2017-11-01 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues. Sci Rep, 8, 2018
5YQ0	Crystal structure of secreted protein CofJ from ETEC. 分子名称: CALCIUM ION, CofJ 著者 Oki, H, Kawahara, K, Maruno, T, Imai, T, Muroga, Y, Fukakusa, S, Iwashita, T, Kobayashi, Y, Matsuda, S, Kodama, T, Iida, T, Yoshida, T, Ohkubo, T, Nakamura, S. 登録日 2017-11-04 公開日 2018-06-27 最終更新日 2018-07-25 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Interplay of a secreted protein with type IVb pilus for efficient enterotoxigenicEscherichia colicolonization Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5XZE	Mouse cGAS bound to the inhibitor RU332 分子名称: (3R)-3-[1-(3H-1lambda~4~,3-benzothiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-2-benzofuran-1(3H)-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... 著者 Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. 登録日 2017-07-12 公開日 2017-10-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.177 Å) 主引用文献 Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun, 8, 2017
5W3H	Yeast microtubule stabilized with epothilone 分子名称: EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Howes, S.C, Geyer, E.A, LaFrance, B, Zhang, R, Kellogg, E.H, Westermann, S, Rice, L.M, Nogales, E. 登録日 2017-06-07 公開日 2017-07-19 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural differences between yeast and mammalian microtubules revealed by cryo-EM. J. Cell Biol., 216, 2017
2MVF	Structural insight into an essential assembly factor network on the pre-ribosome 分子名称: Uncharacterized protein 著者 Lee, W, Bassler, J, Paternoga, H, Holdermann, I, Thomas, M, Granneman, S, Barrio-Garcia, C, Nyarko, A, Stier, G, Clark, S.A, Schraivogel, D, Kallas, M, Beckmann, R, Tollervey, D, Barbar, E, Sinning, I, Hurt, E. 登録日 2014-10-02 公開日 2014-12-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
5Y8U	Crystal structure of the C276S mutant of MAP2K7 分子名称: Dual specificity mitogen-activated protein kinase kinase 7 著者 Kinoshita, T. 登録日 2017-08-21 公開日 2017-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7 Biochem. Biophys. Res. Commun., 493, 2017
5YP1	Crystal structure of dipeptidyl peptidase IV (DPP IV) from Pseudoxanthomonas mexicana WO24 分子名称: Dipeptidyl aminopeptidase 4, GLYCEROL 著者 Roppongi, S, Suzuki, Y, Tateoka, C, Fuimoto, M, Morisawa, S, Iizuka, I, Nakamura, A, Honma, N, Shida, Y, Ogasawara, W, Tanaka, N, Sakamoto, Y, Nonaka, T. 登録日 2017-11-01 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues. Sci Rep, 8, 2018
5YRH	Crystal structure of PPL3B 分子名称: PPL3-a, PPL3-b, SULFATE ION 著者 Nakae, S, Shionyu, M, Ogawa, T, Shirai, T. 登録日 2017-11-09 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization Proteins, 86, 2018
2N4E	Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 分子名称: OR34 著者 Liu, G, Chan, K, Basanta, B, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2015-06-17 公開日 2015-12-09 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 To be Published
5YAL	Ferulic acid esterase from Streptomyces cinnamoneus at 1.5 A resolution 分子名称: ACETATE ION, Esterase, GLYCEROL, ... 著者 Tamura, H, Uraji, M, Mizohata, E, Ogawa, K, Inoue, T, Hatanaka, T. 登録日 2017-09-01 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Loop of Streptomyces Feruloyl Esterase Plays an Important Role in the Enzyme's Catalyzing the Release of Ferulic Acid from Biomass. Appl. Environ. Microbiol., 84, 2018
2OGW	Structure of ABC type zinc transporter from E. coli 分子名称: High-affinity zinc uptake system protein znuA precursor, ZINC ION 著者 Sharma, A, Yogavel, M. 登録日 2007-01-09 公開日 2007-03-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structural Analysis of ABC-family Periplasmic Zinc Binding Protein Provides New Insights Into Mechanism of Ligand Uptake and Release J.Mol.Biol., 367, 2007
5YRM	PPL3C-isomaltose complex 分子名称: PPL3-b, SULFATE ION, alpha-D-glucopyranose-(1-6)-beta-D-glucopyranose 著者 Nakae, S, Shionyu, M, Ogawa, T, Shirai, T. 登録日 2017-11-09 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization Proteins, 86, 2018
5XZG	Mouse cGAS bound to the inhibitor RU521 分子名称: 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... 著者 Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. 登録日 2017-07-12 公開日 2017-10-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.828 Å) 主引用文献 Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun, 8, 2017
5YRI	PPL3B-trehalose complex 分子名称: PPL3-a, PPL3-b, SULFATE ION, ... 著者 Nakae, S, Shionyu, M, Ogawa, T, Shirai, T. 登録日 2017-11-09 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization Proteins, 86, 2018
5YGX	Structure of BACE1 in complex with N-(3-((4R,5R,6S)-2-amino-6-(1,1-difluoroethyl)-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Nakahara, K, Fuchino, K, Komano, K, Asada, N, Tadano, G, Hasegawa, T, Yamamoto, T, Sako, Y, Ogawa, M, Unemura, C, Hosono, M, Sakaguchi, G, Ando, S, Ohnishi, S, Kido, Y, Fukushima, T, Dhuyvetter, D, Borghys, H, Gijsen, H, Yamano, Y, Iso, Y, Kusakabe, K. 登録日 2017-09-27 公開日 2018-08-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine beta-Secretase (BACE1) Inhibitors via Active Conformation Stabilization J. Med. Chem., 61, 2018
5YRJ	PPL3B-isomaltose complex 分子名称: PPL3-a, PPL3-b, SULFATE ION, ... 著者 Nakae, S, Shionyu, M, Ogawa, T, Shirai, T. 登録日 2017-11-09 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization Proteins, 86, 2018

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