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1PGO
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CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
分子名称: 6-PHOSPHOGLUCONATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Adams, M.J, Phillips, C, Gover, S.
登録日1994-07-18
公開日1995-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PBB
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CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
分子名称: 2,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
著者Schreuder, H.A, Mattevi, A, Hol, W.G.J.
登録日1994-07-06
公開日1994-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PIG
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PIG PANCREATIC ALPHA-AMYLASE COMPLEXED WITH THE OLIGOSACCHARIDE V-1532
分子名称: 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ...
著者Machius, M, Vertesy, L, Huber, R, Wiegand, G.
登録日1996-06-15
公開日1996-12-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics.
J.Mol.Biol., 260, 1996
1PCZ
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STRUCTURE OF TATA-BINDING PROTEIN
分子名称: TATA-BINDING PROTEIN
著者Dedecker, B.S, Sigler, P.B.
登録日1996-10-04
公開日1997-01-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of a hyperthermophilic archaeal TATA-box binding protein.
J.Mol.Biol., 264, 1996
1PGG
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PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), TRANS MODEL
分子名称: 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Loll, P.J, Picot, D, Garavito, R.M.
登録日1995-12-02
公開日1997-01-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Biochemistry, 35, 1996
1PHZ
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STRUCTURE OF PHOSPHORYLATED PHENYLALANINE HYDROXYLASE
分子名称: FE (III) ION, PROTEIN (PHENYLALANINE HYDROXYLASE)
著者Kobe, B, Jennings, I.G, House, C.M, Michell, B.J, Cotton, R.G, Kemp, B.E.
登録日1998-11-11
公開日1999-04-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of autoregulation of phenylalanine hydroxylase.
Nat.Struct.Biol., 6, 1999
1DQ9
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COMPLEX OF CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG-COA
分子名称: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, PROTEIN (HMG-COA REDUCTASE)
著者Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J.
登録日1999-12-30
公開日2000-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.
EMBO J., 19, 2000
1PI4
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Structure of N289A mutant of AmpC in complex with SM3, a phenylglyclboronic acid bearing the cephalothin R1 side chain
分子名称: (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION, ...
著者Roth, T.A, Minasov, G, Focia, P.J, Shoichet, B.K.
登録日2003-05-29
公開日2004-02-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Thermodynamic cycle analysis and inhibitor design against beta-lactamase.
Biochemistry, 42, 2003
1DQA
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH HMG, COA, AND NADP+
分子名称: 3-HYDROXY-3-METHYL-GLUTARIC ACID, COENZYME A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Istvan, E.S, Palnitkar, M, Buchanan, S.K, Deisenhofer, J.
登録日1999-12-30
公開日2000-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis.
EMBO J., 19, 2000
1PDA
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STRUCTURE OF PORPHOBILINOGEN DEAMINASE REVEALS A FLEXIBLE MULTIDOMAIN POLYMERASE WITH A SINGLE CATALYTIC SITE
分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID, PORPHOBILINOGEN DEAMINASE
著者Louie, G.V, Brownlie, P.D, Lambert, R, Cooper, J.B, Blundell, T.L, Wood, S.P, Warren, M.J, Woodcock, S.C, Jordan, P.M.
登録日1992-11-17
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site.
Nature, 359, 1992
1PDN
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CRYSTAL STRUCTURE OF A PAIRED DOMAIN-DNA COMPLEX AT 2.5 ANGSTROMS RESOLUTION REVEALS STRUCTURAL BASIS FOR PAX DEVELOPMENTAL MUTATIONS
分子名称: DNA (5'-D(*AP*AP*CP*GP*TP*CP*AP*CP*GP*GP*TP*TP*GP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*CP*AP*AP*CP*CP*GP*TP*GP*AP*CP*G)-3'), PROTEIN (PRD PAIRED)
著者Xu, W, Rould, M.A, Jun, S, Desplan, C, Pabo, C.O.
登録日1995-05-16
公開日1995-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations.
Cell(Cambridge,Mass.), 80, 1995
1PDV
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Crystal structure of human DJ-1, P 31 2 1 space group
分子名称: DJ-1
著者Tao, X, Tong, L.
登録日2003-05-20
公開日2003-06-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
1PGP
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CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
分子名称: 6-PHOSPHOGLUCONATE DEHYDROGENASE, 6-PHOSPHOGLUCONIC ACID, SULFATE ION
著者Adams, M.J, Phillips, C, Gover, S, Naylor, C.E.
登録日1994-07-18
公開日1995-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PEX
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COLLAGENASE-3 (MMP-13) C-TERMINAL HEMOPEXIN-LIKE DOMAIN
分子名称: CALCIUM ION, CHLORIDE ION, COLLAGENASE-3, ...
著者Gomis-Ruth, F.X, Gohlke, U, Betz, M, Knauper, V, Murphy, G, Lopez-Otin, C, Bode, W.
登録日1996-05-24
公開日1996-12-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The helping hand of collagenase-3 (MMP-13): 2.7 A crystal structure of its C-terminal haemopexin-like domain.
J.Mol.Biol., 264, 1996
1PEN
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ALPHA-CONOTOXIN PNI1
分子名称: ALPHA-CONOTOXIN PNIA
著者Hu, S.-H, Gehrmann, J, Guddat, L.W, Alewood, P.F, Craik, D.J, Martin, J.L.
登録日1996-01-29
公開日1997-04-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.
Structure, 4, 1996
1PHK
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TWO STRUCTURES OF THE CATALYTIC DOMAIN OF PHOSPHORYLASE, KINASE: AN ACTIVE PROTEIN KINASE COMPLEXED WITH NUCLEOTIDE, SUBSTRATE-ANALOGUE AND PRODUCT
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PHOSPHORYLASE KINASE
著者Owen, D.J, Noble, M.E.M, Garman, E.F, Papageorgiou, A.C, Johnson, L.N.
登録日1996-03-15
公開日1996-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product.
Structure, 3, 1995
1PFX
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PORCINE FACTOR IXA
分子名称: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, FACTOR IXA
著者Brandstetter, H, Bauer, M, Huber, R, Lollar, P, Bode, W.
登録日1995-07-19
公開日1996-08-17
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.
Proc.Natl.Acad.Sci.USA, 92, 1995
1PGN
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CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
分子名称: 6-PHOSPHOGLUCONATE DEHYDROGENASE, NICOTINAMIDE 8-BROMO-ADENINE DINUCLEOTIDE PHOSPHATE, PYROPHOSPHATE 2-, ...
著者Adams, M.J, Phillips, C, Gover, S.
登録日1994-07-18
公開日1995-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PED
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BACTERIAL SECONDARY ALCOHOL DEHYDROGENASE (APO-FORM)
分子名称: NADP-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION
著者Korkhin, Y, Frolow, F.
登録日1995-12-28
公開日1997-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystalline alcohol dehydrogenases from the mesophilic bacterium Clostridium beijerinckii and the thermophilic bacterium Thermoanaerobium brockii: preparation, characterization and molecular symmetry.
Acta Crystallogr.,Sect.D, 52, 1996
1PGQ
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CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM
分子名称: 6-PHOSPHOGLUCONATE DEHYDROGENASE, ADENOSINE-2'-MONOPHOSPHATE, SULFATE ION
著者Adams, M.J, Phillips, C, Gover, S.
登録日1994-07-18
公開日1995-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
1PIO
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AN ENGINEERED STAPHYLOCOCCUS AUREUS PC1 BETA-LACTAMASE THAT HYDROLYSES THIRD GENERATION CEPHALOSPORINS
分子名称: BETA-LACTAMASE
著者Zawadzke, L.E, Herzberg, O.
登録日1995-10-11
公開日1996-03-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献An engineered Staphylococcus aureus PC1 beta-lactamase that hydrolyses third-generation cephalosporins.
Protein Eng., 8, 1995
1PAU
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Crystal structure of the complex of apopain with the tetrapeptide aldehyde inhibitor AC-DEVD-CHO
分子名称: ACE-ASP-GLU-VAL-ASJ, APOPAIN
著者Rotonda, J, Becker, J.W.
登録日1996-06-06
公開日1997-07-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.
Nat.Struct.Biol., 3, 1996
1PBC
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CRYSTAL STRUCTURES OF WILD-TYPE P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE, 2,4-DIHYDROXYBENZOATE AND 2-HYDROXY-4-AMINOBENZOATE AND OF THE TRY222ALA MUTANT, COMPLEXED WITH 2-HYDROXY-4-AMINOBENZOATE. EVIDENCE FOR A PROTON CHANNEL AND A NEW BINDING MODE OF THE FLAVIN RING
分子名称: 2-HYDROXY-4-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE
著者Schreuder, H.A, Van Der Bolt, F.J.T, Van Berkel, W.J.H.
登録日1994-07-06
公開日1994-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate,2,4-dihydroxybenzoate, and 2-hydroxy-4-aminobenzoate and of the Tyr222Ala mutant complexed with 2-hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
Biochemistry, 33, 1994
1PDH
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CRYSTAL STRUCTURE OF P-HYDROXYBENZOATE HYDROXYLASE RECONSTITUTED WITH THE MODIFIED FAD PRESENT IN ALCOHOL OXIDASE FROM METHYLOTROPHIC YEASTS: EVIDENCE FOR AN ARABINOFLAVIN
分子名称: ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
著者Schreuder, H.A, Eppink, M.H.M, Van Berkel, W.J.H.
登録日1994-12-01
公開日1995-03-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of p-hydroxybenzoate hydroxylase reconstituted with the modified FAD present in alcohol oxidase from methylotrophic yeasts: evidence for an arabinoflavin.
Protein Sci., 3, 1994
1PBW
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STRUCTURE OF BCR-HOMOLOGY (BH) DOMAIN
分子名称: PHOSPHATIDYLINOSITOL 3-KINASE
著者Musacchio, A, Cantley, L.C, Harrison, S.C.
登録日1996-10-17
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunit.
Proc.Natl.Acad.Sci.USA, 93, 1996

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