PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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3LP2	HIV-1 reverse transcriptase with inhibitor 分子名称: 3-[4-(diethylamino)phenoxy]-6-(ethoxycarbonyl)-5,8-dihydroxy-7-oxo-7,8-dihydro-1,8-naphthyridin-1-ium, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... 著者 Yan, Y, Munshi, S.K, Prasad, G.S, Su, H.P. 登録日 2010-02-04 公開日 2010-06-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. J.Virol., 84, 2010
7R3W	Crystal structure of the albicidin resistance protein STM3175 from Salmonella typhimurium 分子名称: Putative bacterial regulatory helix-turn-helix protein 著者 Dimos, N, Kosol, S, Suessmuth, R, Loll, B. 登録日 2022-02-08 公開日 2022-09-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria. Plos Biol., 21, 2023
3LP1	HIV-1 reverse transcriptase with inhibitor 分子名称: 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 3-cyclopentyl-1,4-dihydroxy-1,8-naphthyridin-2(1H)-one, MANGANESE (II) ION, ... 著者 Yan, Y, Munshi, S.K, Prasad, G.S, Su, H.P. 登録日 2010-02-04 公開日 2010-06-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. J.Virol., 84, 2010
8RPZ	Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation I 分子名称: 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 88, ... 著者 Lauer, S, Nikolay, R, Spahn, C. 登録日 2024-01-17 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.44 Å) 主引用文献 Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
8H7G	Cryo-EM structure of the human SAGA complex 分子名称: Ataxin-7, STAGA complex 65 subunit gamma, Splicing factor 3B subunit 3, ... 著者 Huang, J, Zhang, Y. 登録日 2022-10-20 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of human SAGA transcriptional coactivator complex. Cell Discov, 8, 2022
6YR2	TetR(D) soaked with Tigecycline P4(1)2(1)2 分子名称: CHLORIDE ION, MAGNESIUM ION, SULFATE ION, ... 著者 Hinrichs, W, Stary, K. 登録日 2020-04-19 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 TetR(D) soaked with Tigecycline to be published
6YR1	TetR(D) soaked with Tigecycline I4(1)22 分子名称: CHLORIDE ION, MAGNESIUM ION, TIGECYCLINE, ... 著者 Hinrichs, W, Stary, K. 登録日 2020-04-18 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 TetR(D) soaked with Tigecycline to be published
5NO2	RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate) 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. 登録日 2017-04-10 公開日 2017-05-24 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (5.16 Å) 主引用文献 RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Res., 45, 2017
8QBT	E. coli ApdP-stalled ribosomal complex 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... 著者 Morici, M, Wilson, D.N. 登録日 2023-08-25 公開日 2024-03-20 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity. Nat Commun, 15, 2024
5NO3	RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate without uS3) 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. 登録日 2017-04-10 公開日 2017-05-31 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (5.16 Å) 主引用文献 RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Res., 45, 2017
6YLH	Rix1-Rea1 pre-60S particle - full composite structure 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Kater, L, Beckmann, R. 登録日 2020-04-07 公開日 2020-07-29 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Mol.Cell, 79, 2020
2O7O	Crystal structure analysis of TetR(D) complex with doxycycline 分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ... 著者 Aleksandrov, A, Proft, J, Hinrichs, W. 登録日 2006-12-11 公開日 2007-05-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Protonation Patterns in Tetracycline:Tet Repressor Recognition: Simulations and Experiments Chembiochem, 8, 2007
7NSQ	Structure of ErmDL-Telithromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Beckert, B, Wilson, D.N. 登録日 2021-03-08 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nat Commun, 12, 2021
7NSO	Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with P-tRNA 分子名称: 16S rRNA (1540-MER), 23S rRNA (2903-MER), 30S ribosomal protein S10, ... 著者 Beckert, B, Wilson, D.N. 登録日 2021-03-08 公開日 2021-07-14 最終更新日 2021-08-11 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nat Commun, 12, 2021
7NSP	Structure of ErmDL-Erythromycin-stalled 70S E. coli ribosomal complex with A and P-tRNA 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Beckert, B, Wilson, D.N. 登録日 2021-03-08 公開日 2021-08-11 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics. Nat Commun, 12, 2021
2O8X	Crystal structure of the "-35 element" promoter recognition domain of Mycobacterium tuberculosis SigC 分子名称: Probable RNA polymerase sigma-C factor, SULFATE ION 著者 Thakur, K.G, Joshi, A.M, Gopal, B. 登録日 2006-12-12 公開日 2006-12-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and biophysical studies on two promoter recognition domains of the extra-cytoplasmic function sigma factor sigma(C) from Mycobacterium tuberculosis. J.Biol.Chem., 282, 2007
8QFD	UFL1 E3 ligase bound 60S ribosome 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Makhlouf, L, Kulathu, Y, Zeqiraj, E. 登録日 2023-09-04 公開日 2024-02-21 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
8RPY	Escherichia coli 50S subunit in complex with the antimicrobial peptide Api137 分子名称: 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 137, ... 著者 Lauer, S, Nikolay, R, Spahn, C. 登録日 2024-01-17 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
8RQ0	Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation II 分子名称: 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 88, ... 著者 Lauer, S, Nikolay, R, Spahn, C. 登録日 2024-01-17 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.44 Å) 主引用文献 Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
8RQ2	Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation III 分子名称: 23S ribosomal RNA, 5S ribosomal RNA, Apidaecins type 88, ... 著者 Lauer, S, Nikolay, R, Spahn, C. 登録日 2024-01-17 公開日 2024-05-22 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.44 Å) 主引用文献 Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88. Nat Commun, 15, 2024
5NO4	RsgA-GDPNP bound to the 30S ribosomal subunit (RsgA assembly intermediate with uS3) 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Lopez-Alonso, J.P, Kaminishi, T, Kikuchi, T, Hirata, Y, Iturrioz, I, Dhimole, N, Schedlbauer, A, Hase, Y, Goto, S, Kurita, D, Muto, A, Zhou, S, Naoe, C, Mills, D.J, Gil-Carton, D, Takemoto, C, Himeno, H, Fucini, P, Connell, S.R. 登録日 2017-04-10 公開日 2017-05-31 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (5.16 Å) 主引用文献 RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket. Nucleic Acids Res., 45, 2017
7NWT	Initiated 70S ribosome in complex with 2A protein from encephalomyocarditis virus (EMCV) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Hill, C.H, Napthine, S, Pekarek, L, Kibe, A, Firth, A.E, Graham, S.C, Caliskan, N, Brierley, I. 登録日 2021-03-17 公開日 2021-12-15 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch Nat Commun, 12, 2021
7NWW	CspA-27 cotranslational folding intermediate 1 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. 登録日 2021-03-17 公開日 2022-01-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
7OIF	CspA-27 cotranslational folding intermediate 2 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. 登録日 2021-05-11 公開日 2022-01-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022
7OIG	CspA-27 cotranslational folding intermediate 3 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. 登録日 2021-05-11 公開日 2022-01-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A switch from alpha-helical to beta-strand conformation during co-translational protein folding. Embo J., 41, 2022

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