PDB: 3116 件ウェブページステータス検索Chemie searchBIRD

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5FDU	Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A. 登録日 2015-12-16 公開日 2016-01-27 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. Nucleic Acids Res., 44, 2016
5FDV	Crystal structure of the Pyrrhocoricin antimicrobial peptide bound to the Thermus thermophilus 70S ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A. 登録日 2015-12-16 公開日 2016-01-27 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. Nucleic Acids Res., 44, 2016
5EL7	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the second position and antibiotic paromomycin 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-11-04 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5FCI	Structure of the vacant uL3 W255C mutant 80S yeast ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M. 登録日 2015-12-15 公開日 2016-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency. J.Mol.Biol., 428, 2016
5EIR	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, SULFATE ION, ... 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-30 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
5EL4	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-11-04 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5E81	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with wobble pair 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-10-13 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5EI3	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: Eukaryotic translation initiation factor 4 gamma, Eukaryotic translation initiation factor 4E, SULFATE ION, ... 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-29 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
5EKV	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-11-04 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.61 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
5EL5	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the second position 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-11-04 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5EL6	Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position and antibiotic paromomycin 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. 登録日 2015-11-04 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
5EHC	Co-crystal structure of eIF4E with nucleotide mimetic inhibitor. 分子名称: 3-[[(2~{R},3~{S},4~{R},5~{R})-5-[2-azanyl-7-[(3-chlorophenyl)methyl]-6-oxidanylidene-1~{H}-purin-7-ium-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-4-oxidanyl-cyclobut-3-ene-1,2-dione, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E 著者 Nowicki, M.W, Walkinshaw, M.D, Fischer, P.M. 登録日 2015-10-28 公開日 2016-09-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur.J.Med.Chem., 124, 2016
5GAD	RNC-SRP-SR complex early state 分子名称: 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... 著者 Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. 登録日 2015-11-24 公開日 2016-01-27 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
5HL7	The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Eyal, Z, Matzov, D, Krupkin, M, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. 登録日 2016-01-14 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism. Sci Rep, 6, 2016
5HCR	Crystal structure of antimicrobial peptide Oncocin 10wt bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
5HCQ	Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
5GAF	RNC in complex with SRP 分子名称: 1A9L SS, 23S ribosomal RNA, 50S ribosomal protein L10, ... 著者 Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. 登録日 2015-11-25 公開日 2016-02-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon Nat Commun, 7, 2016
5H2F	Crystal structure of the PsbM-deletion mutant of photosystem II 分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Uto, S, Kawakami, K, Umena, Y, Iwai, M, Ikeuchi, M, Shen, J.R, Kamiya, N. 登録日 2016-10-15 公開日 2017-03-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mutual relationships between structural and functional changes in a PsbM-deletion mutant of photosystem II. Faraday Discuss., 198, 2017
5HAU	Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2015-12-30 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
5GAH	RNC in complex with SRP with detached NG domain 分子名称: 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... 著者 Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. 登録日 2015-11-26 公開日 2016-01-27 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
5HD1	Crystal structure of antimicrobial peptide Pyrrhocoricin bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
5HCP	Crystal structure of antimicrobial peptide Metalnikowin bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.894 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
5HKV	The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23s ribosomal RNA, 50S ribosomal protein L13, ... 著者 Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M. 登録日 2016-01-14 公開日 2017-05-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.66 Å) 主引用文献 Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus. Nucleic Acids Res., 45, 2017
6X80	Structure of the Campylobacter jejuni G508A Flagellar Filament 分子名称: 5,7-diamino-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-non-2-ulopyranosonic acid, Flagellin A 著者 Kreutzberger, M.A.B, Wang, F, Egelman, E.H. 登録日 2020-06-01 公開日 2020-07-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Atomic structure of the Campylobacter jejuni flagellar filament reveals how epsilon Proteobacteria escaped Toll-like receptor 5 surveillance. Proc.Natl.Acad.Sci.USA, 117, 2020
6XHX	Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S. 登録日 2020-06-19 公開日 2020-12-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nat.Chem.Biol., 17, 2021

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