PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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4BIV	Crystal structure of CpxAHDC (trigonal form) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, SENSOR PROTEIN CPXA 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4BIY	Crystal structure of CpxAHDC (monoclinic form 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4CB0	Crystal structure of CpxAHDC in complex with ATP (hexagonal form) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-10-09 公開日 2014-02-12 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation. Plos Biol., 12, 2014
4CTI	Escherichia coli EnvZ histidine kinase catalytic part fused to Archaeoglobus fulgidus Af1503 HAMP domain 分子名称: OSMOLARITY SENSOR PROTEIN ENVZ, AF1503 著者 Ferris, H.U, Coles, M, Lupas, A.N, Hartmann, M.D. 登録日 2014-03-13 公開日 2014-04-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.847 Å) 主引用文献 Crystallographic Snapshot of the Escherichia Coli Envz Histidine Kinase in an Active Conformation. J.Struct.Biol., 186, 2014
4BIZ	Crystal structure of CpxAHDC (orthorhombic form 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION 著者 Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M. 登録日 2013-04-13 公開日 2014-04-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structures of Cpxahdc To be Published
4Q20	Crystal structure of a C-terminal part of tyrosine kinase (DivL) from Caulobacter crescentus CB15 at 2.50 A resolution (PSI Community Target, Shapiro) 分子名称: Sensor protein DivL 著者 Joint Center for Structural Genomics (JCSG) 登録日 2014-04-04 公開日 2014-04-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Cell fate regulation governed by a repurposed bacterial histidine kinase. Plos Biol., 12, 2014
4URO	Crystal Structure of Staph GyraseB 24kDa in complex with Novobiocin 分子名称: DNA GYRASE SUBUNIT B, NOVOBIOCIN 著者 Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B. 登録日 2014-07-01 公開日 2014-07-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode. Acs Chem.Biol., 9, 2014
4URM	Crystal Structure of Staph GyraseB 24kDa in complex with Kibdelomycin 分子名称: (1R,4aS,5S,6S,8aR)-5-{[(5S)-1-(3-O-acetyl-4-O-carbamoyl-6-deoxy-2-O-methyl-alpha-L-talopyranosyl)-4-hydroxy-2-oxo-5-(propan-2-yl)-2,5-dihydro-1H-pyrrol-3-yl]carbonyl}-6-methyl-4-methylidene-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl 2,6-dideoxy-3-C-[(1S)-1-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}ethyl]-beta-D-ribo-hexopyranoside, DNA GYRASE SUBUNIT B 著者 Lu, J, Patel, S, Sharma, N, Soisson, S, Kishii, R, Takei, M, Fukuda, Y, Lumb, K.J, Singh, S.B. 登録日 2014-06-30 公開日 2014-07-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode. Acs Chem.Biol., 9, 2014
4PRX	E. coli GyrB 43-kDa N-terminal fragment in complex with ADP+Pi 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, GyrB, ... 著者 Stanger, F.V, Schirmer, T. 登録日 2014-03-06 公開日 2014-09-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis Plos One, 9, 2014
4R1F	Re-refined Human DNA topoisomerase IIa (ATPase and transducer domains) in complex with ADP and SO4 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA topoisomerase 2-alpha, GLYCEROL, ... 著者 Stanger, F.V, Schirmer, T. 登録日 2014-08-05 公開日 2014-09-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis Plos One, 9, 2014
4PU9	E. coli GyrB 43-kDa N-terminal fragment in complex with ADP-BeF3 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GyrB, ... 著者 Stanger, F.V, Schirmer, T. 登録日 2014-03-12 公開日 2014-09-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis Plos One, 9, 2014
4PRV	E. coli GyrB 43-kDa N-terminal fragment in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, GyrB, MAGNESIUM ION 著者 Stanger, F.V, Schirmer, T. 登録日 2014-03-06 公開日 2014-09-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis Plos One, 9, 2014
4P8O	S. aureus gyrase bound to an aminobenzimidazole urea inhibitor 分子名称: 1-ethyl-3-[5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzimidazol-2-yl]urea, DNA gyrase subunit B 著者 Jacobs, M.D. 登録日 2014-03-31 公開日 2014-10-29 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Second-generation antibacterial benzimidazole ureas: discovery of a preclinical candidate with reduced metabolic liability. J.Med.Chem., 57, 2014
4V26	VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells 分子名称: MAGNESIUM ION, N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, N-[4-(2-CHLORO-5-METHYLPYRIMIDIN-4-YL)PHENYL]-2,4-DIHYDROXY-N-(4-{[(TRIFLUOROACETYL)AMINO]METHYL}BENZYL)BENZAMIDE, ... 著者 Moore, J.D, Staniszewska, A, Shaw, T, D'Alessandro, J, Davis, B, Surgenor, A, Baker, L, Matassova, N, Murray, J, Macias, A, Brough, P, Wood, M, Mahon, P.C. 登録日 2014-10-06 公開日 2014-12-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells. Oncotarget, 5, 2014
4V25	VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context- dependent cytostasis in cancer cells 分子名称: MAGNESIUM ION, N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE, N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-N-(4-{[(difluoroacetyl)amino]methyl}benzyl)-2,4-dihydroxybenzamide, ... 著者 Moore, J.D, Staniszewska, A, Shaw, T, D'Alessandro, J, Davis, B, Surgenor, A, Baker, L, Matassova, N, Murray, J, Macias, A, Brough, P, Wood, M, Mahon, P.C. 登録日 2014-10-06 公開日 2014-12-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells. Oncotarget, 5, 2014
4R39	Histidine kinase domain from Erythrobacter litoralis EL346 blue-light activated histidine kinase 分子名称: Blue-light-activated histidine kinase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Tomchick, D.R, Rivera-Cancel, G, Gardner, K.H. 登録日 2014-08-14 公開日 2014-12-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation. Proc.Natl.Acad.Sci.USA, 111, 2014
4R3A	Erythrobacter litoralis EL346 blue-light activated histidine kinase 分子名称: Blue-light-activated histidine kinase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Tomchick, D.R, Rivera-Cancel, G, Gardner, K.H. 登録日 2014-08-14 公開日 2014-12-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation. Proc.Natl.Acad.Sci.USA, 111, 2014
4PL9	Structure of the catalytic domain of ETR1 from Arabidopsis thaliana 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, ... 著者 Panneerselvam, S, Mueller-Dieckmann, J. 登録日 2014-05-16 公開日 2014-12-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Model of the Cytosolic Domain of the Plant Ethylene Receptor 1 (ETR1). J.Biol.Chem., 290, 2015
4XKK	Crystal structure of N-terminal domain of Hsp90 from Dictyostelium discoideum 分子名称: Heat shock cognate 90 kDa protein 著者 Raman, S, Suguna, K. 登録日 2015-01-12 公開日 2015-01-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Heat shock protein 90 regulates development in Dictyostelium discoideum J. Mol. Biol., 383, 2008
4XTJ	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from 100 mM KCl plus 100 mM NaCl condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2015-01-23 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
4WUB	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from 100 mM KCl condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2014-10-31 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
4WUC	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from 100 mM NaCl condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2014-10-31 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
4WUD	N-terminal 43 kDa fragment of the E. coli DNA gyrase B subunit grown from no salt condition 分子名称: CHLORIDE ION, DNA gyrase subunit B, MAGNESIUM ION, ... 著者 Hearnshaw, S.J, Chung, T.T, Stevenson, C.E.M, Maxwell, A, Lawson, D.M. 登録日 2014-10-31 公開日 2015-04-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The role of monovalent cations in the ATPase reaction of DNA gyrase Acta Crystallogr.,Sect.D, 71, 2015
5BOC	Crystal structure of topoisomerase ParE inhibitor 分子名称: 3-methyl-4-({3-[3-methyl-5-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)benzoic acid, DNA topoisomerase 4 subunit B 著者 Tan, Y.W, Chen, G.Y, Hung, A.W, Hill, J. 登録日 2015-05-27 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Application of Fragment-based Drug Discovery against DNA GyraseB To be published
5BOD	Crystal structure of Streptococcus pneumonia ParE inhibitor 分子名称: (2R)-N-[3-(3,5-dimethylphenyl)-1H-pyrazol-5-yl]-1,4-dioxane-2-carboxamide, DNA topoisomerase 4 subunit B 著者 Tan, Y.W, Chen, G, Hung, A.W, Hill, J. 登録日 2015-05-27 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Application of Fragment-based Drug Discovery against DNA GyraseB to be published

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