7D43
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![BU of 7d43 by Molmil](/molmil-images/mine/7d43) | eIF2B-eIF2(aP), aPg complex | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | 著者 | Kashiwagi, K, Ito, T. | 登録日 | 2020-09-22 | 公開日 | 2020-12-09 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B. Mol.Cell, 81, 2021
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2A1A
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![BU of 2a1a by Molmil](/molmil-images/mine/2a1a) | PKR kinase domain-eIF2alpha Complex | 分子名称: | Eukaryotic translation initiation factor 2 alpha subunit, Interferon-induced, double-stranded RNA-activated protein kinase | 著者 | Dar, A.C, Dever, T.E, Sicheri, F. | 登録日 | 2005-06-19 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR. Cell(Cambridge,Mass.), 122, 2005
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2AHO
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![BU of 2aho by Molmil](/molmil-images/mine/2aho) | Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus solfataricus complexed with GDPNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Translation initiation factor 2 alpha subunit, ... | 著者 | Yatime, L, Mechulam, Y, Blanquet, S, Schmitt, E. | 登録日 | 2005-07-28 | 公開日 | 2006-01-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Switch of the gamma Subunit in an Archaeal aIF2alphagamma Heterodimer Structure, 14, 2006
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8A3L
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![BU of 8a3l by Molmil](/molmil-images/mine/8a3l) | Structural insights into the binding of bS1 to the ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... | 著者 | D'Urso, G, Chat, S, Gillet, R, Giudice, E. | 登録日 | 2022-06-08 | 公開日 | 2023-05-10 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Structural insights into the binding of bS1 to the ribosome. Nucleic Acids Res., 51, 2023
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8A40
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![BU of 8a40 by Molmil](/molmil-images/mine/8a40) | Structure of mammalian Pol II-TFIIS elongation complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. | 登録日 | 2022-06-09 | 公開日 | 2023-08-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
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2JA7
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![BU of 2ja7 by Molmil](/molmil-images/mine/2ja7) | CPD lesion containing RNA Polymerase II elongation complex C | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TTP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... | 著者 | Brueckner, F, Hennecke, U, Carell, T, Cramer, P. | 登録日 | 2006-11-23 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Cpd Damage Recognition by Transcribing RNA Polymerase II. Science, 315, 2007
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2JA6
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![BU of 2ja6 by Molmil](/molmil-images/mine/2ja6) | CPD lesion containing RNA Polymerase II elongation complex B | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TTP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... | 著者 | Brueckner, F, Hennecke, U, Carell, T, Cramer, P. | 登録日 | 2006-11-23 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | CPD damage recognition by transcribing RNA polymerase II. Science, 315, 2007
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2JA5
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![BU of 2ja5 by Molmil](/molmil-images/mine/2ja5) | CPD lesion containing RNA Polymerase II elongation complex A | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TTP*TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Brueckner, F, Hennecke, U, Carell, T, Cramer, P. | 登録日 | 2006-11-23 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Cpd Damage Recognition by Transcribing RNA Polymerase II Science, 315, 2007
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8B3F
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![BU of 8b3f by Molmil](/molmil-images/mine/8b3f) | Pol II-CSB-CSA-DDB1-ELOF1 | 分子名称: | DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... | 著者 | Kokic, G, Cramer, P. | 登録日 | 2022-09-16 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Pol II-CSB-CSA-DDB1-ELOF1 structure. To Be Published
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8B3D
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![BU of 8b3d by Molmil](/molmil-images/mine/8b3d) | |
2JA8
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![BU of 2ja8 by Molmil](/molmil-images/mine/2ja8) | CPD lesion containing RNA Polymerase II elongation complex D | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *CP*TP*TP*TP*TP*TTP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*AP*UP)-3', ... | 著者 | Brueckner, F, Hennecke, U, Carell, T, Cramer, P. | 登録日 | 2006-11-23 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Cpd Damage Recognition by Transcribing RNA Polymerase II. Science, 315, 2007
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7ZSB
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![BU of 7zsb by Molmil](/molmil-images/mine/7zsb) | |
7ZSA
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![BU of 7zsa by Molmil](/molmil-images/mine/7zsa) | |
7ZS9
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![BU of 7zs9 by Molmil](/molmil-images/mine/7zs9) | |
8BVW
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![BU of 8bvw by Molmil](/molmil-images/mine/8bvw) | RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W) | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P. | 登録日 | 2022-12-20 | 公開日 | 2023-05-03 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Mol.Cell, 83, 2023
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8CEO
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![BU of 8ceo by Molmil](/molmil-images/mine/8ceo) | |
8CEN
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![BU of 8cen by Molmil](/molmil-images/mine/8cen) | Yeast RNA polymerase II transcription pre-initiation complex with core Mediator | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Wang, H, Schilbach, S, Cramer, P. | 登録日 | 2023-02-02 | 公開日 | 2023-03-22 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023
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7F4G
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![BU of 7f4g by Molmil](/molmil-images/mine/7f4g) | Structure of RPAP2-bound RNA polymerase II | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | 著者 | Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y. | 登録日 | 2021-06-18 | 公開日 | 2021-07-07 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex. Cell Rep, 39, 2022
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7F67
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![BU of 7f67 by Molmil](/molmil-images/mine/7f67) | eIF2B-SFSV NSs-2-eIF2 | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | 著者 | Kashiwagi, K, Ito, T. | 登録日 | 2021-06-24 | 公開日 | 2021-12-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response. Nat Commun, 12, 2021
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7F66
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![BU of 7f66 by Molmil](/molmil-images/mine/7f66) | eIF2B-SFSV NSs-1-eIF2 | 分子名称: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ... | 著者 | Kashiwagi, K, Ito, T. | 登録日 | 2021-06-24 | 公開日 | 2021-12-01 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | eIF2B-capturing viral protein NSs suppresses the integrated stress response. Nat Commun, 12, 2021
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7EDX
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![BU of 7edx by Molmil](/molmil-images/mine/7edx) | p53-bound TFIID-based core PIC on HDM2 promoter | 分子名称: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-17 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGB
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![BU of 7egb by Molmil](/molmil-images/mine/7egb) | TFIID-based holo PIC on SCP promoter | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG7
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![BU of 7eg7 by Molmil](/molmil-images/mine/7eg7) | TFIID-based core PIC on SCP promoter | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG9
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![BU of 7eg9 by Molmil](/molmil-images/mine/7eg9) | TFIID-based intermediate PIC on SCP promoter | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGA
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![BU of 7ega by Molmil](/molmil-images/mine/7ega) | TFIID-based intermediate PIC on PUMA promoter | 分子名称: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | 登録日 | 2021-03-24 | 公開日 | 2021-05-05 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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