1U2Y
 
 | | In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing D-gluconhydroximo-1,5-lactam | | 分子名称: | (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... | | 著者 | Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G. | | 登録日 | 2004-07-20 | | 公開日 | 2004-09-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors.
J.Biol.Chem., 279, 2004
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5M99
 | | Functional Characterization and Crystal Structure of Thermostable Amylase from Thermotoga petrophila, reveals High Thermostability and an Archaic form of Dimerization | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-amylase, ... | | 著者 | Hameed, U, Price, I, Mirza, O.A. | | 登録日 | 2016-11-01 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Functional characterization and crystal structure of thermostable amylase from Thermotoga petrophila, reveals high thermostability and an unusual form of dimerization.
Biochim. Biophys. Acta, 1865, 2017
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3UCQ
 | | Crystal structure of amylosucrase from Deinococcus geothermalis | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Amylosucrase, GLYCEROL | | 著者 | Guerin, F, Pizzut-Serin, S, Guillet, V, Mourey, L, Potocki-Veronese, G, Remaud-Simeon, M, Andre, I, Tranier, S. | | 登録日 | 2011-10-27 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural Investigation of the Thermostability and Product Specificity of Amylosucrase from the Bacterium Deinococcus geothermalis.
J.Biol.Chem., 287, 2012
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3L2M
 | | X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Alpha-cyclodextrin | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ... | | 著者 | Larson, S.B, Day, J.S, McPherson, A. | | 登録日 | 2009-12-15 | | 公開日 | 2010-04-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin.
Biochemistry, 49, 2010
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2QV4
 | | Human pancreatic alpha-amylase complexed with nitrite and acarbose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5R,6S)-4-{[alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl]oxy}-5,6-dihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose, CALCIUM ION, ... | | 著者 | Williams, L.K, Maurus, R, Brayer, G.D. | | 登録日 | 2007-08-07 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
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7TAA
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6JFX
 | | Crystal structure of Pullulanase from Paenibacillus barengoltzii complex with maltopentaose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Wu, S.W, Yang, S.Q, Qin, Z, You, X, Huang, P, Jiang, Z.Q. | | 登録日 | 2019-02-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Structural basis of carbohydrate binding in domain C of a type I pullulanase from Paenibacillus barengoltzii.
Acta Crystallogr D Struct Biol, 76, 2020
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1JXJ
 | | Role of mobile loop in the mechanism of human salivary amylase | | 分子名称: | Alpha-amylase, salivary, CALCIUM ION, ... | | 著者 | Ramasubbu, N, Ragunath, C, Wang, Z, Mishra, P.J, Thomas, L.M. | | 登録日 | 2001-09-07 | | 公開日 | 2001-09-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity.
Eur.J.Biochem., 271, 2004
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3BAY
 | | N298S Variant of Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ... | | 著者 | Fredriksen, J.R, Maurus, R, Brayer, G.D. | | 登録日 | 2007-11-08 | | 公開日 | 2008-03-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
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1MXD
 | | Structure of a (Ca,Zn)-dependent alpha-amylase from the hyperthermophilic archaeon Pyrococcus woesei | | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | 著者 | Linden, A, Mayans, O, Meyer-Klaucke, W, Antranikian, G, Wilmanns, M. | | 登録日 | 2002-10-02 | | 公開日 | 2003-06-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Differential Regulation of a Hyperthermophilic alpha-Amylase with a Novel (Ca,Zn) Two-metal Center by Zinc
J.Biol.Chem., 278, 2003
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8ORP
 | | Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose | | 分子名称: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | | 著者 | Aghajari, N, Haser, R. | | 登録日 | 2023-04-16 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase.
Molecules, 28, 2023
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1MFU
 | | Probing the role of a mobile loop in human salivary amylase: Structural studies on the loop-deleted mutant | | 分子名称: | 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ... | | 著者 | Ramasubbu, N, Ragunath, C, Mishra, P.J. | | 登録日 | 2002-08-13 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the role of a mobile loop in substrate binding and enzyme activity of
human salivary amylase.
J.Mol.Biol., 325, 2003
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1MW3
 | | Amylosucrase soaked with 1M sucrose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, amylosucrase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Skov, L.K, Mirza, O, Sprogoe, D, Dar, I, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | | 登録日 | 2002-09-27 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
J.BIOL.CHEM., 277, 2002
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1DED
 | | CRYSTAL STRUCTURE OF ALKALOPHILIC ASPARAGINE 233-REPLACED CYCLODEXTRIN GLUCANOTRANSFERASE COMPLEXED WITH AN INHIBITOR, ACARBOSE, AT 2.0 A RESOLUTION | | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, CALCIUM ION, CYCLODEXTRIN GLUCANOTRANSFERASE | | 著者 | Ishii, N, Haga, K, Yamane, K, Harata, K. | | 登録日 | 1999-11-14 | | 公開日 | 2000-04-07 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of alkalophilic asparagine 233-replaced cyclodextrin glucanotransferase complexed with an inhibitor, acarbose, at 2.0 A resolution.
J.Biochem.(Tokyo), 127, 2000
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2GDV
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1WZL
 | | Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) mutatnt R469L | | 分子名称: | Alpha-amylase II, CALCIUM ION | | 著者 | Mizuno, M, Ichikawa, K, Tonozuka, T, Ohtaki, A, Shimura, Y, Kamitori, S, Nishikawa, A, Sakano, Y. | | 登録日 | 2005-03-06 | | 公開日 | 2005-03-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mutagenesis and Structural Analysis of Thermoactinomyces vulgaris R-47 alpha-Amylase II (TVA II)
To be Published
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1AQH
 | | ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS | | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION | | 著者 | Aghajari, N, Haser, R. | | 登録日 | 1997-07-30 | | 公開日 | 1999-02-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor.
Protein Sci., 7, 1998
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1BF2
 | | STRUCTURE OF PSEUDOMONAS ISOAMYLASE | | 分子名称: | CALCIUM ION, ISOAMYLASE | | 著者 | Katsuya, Y, Mezaki, Y, Kubota, M, Matsuura, Y. | | 登録日 | 1998-05-26 | | 公開日 | 1998-08-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of Pseudomonas isoamylase at 2.2 A resolution.
J.Mol.Biol., 281, 1998
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3IJ7
 | | Directed 'in situ' Elongation as a Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic a-Amylase | | 分子名称: | 4-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranosyl fluoride, 4-O-methyl-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-2)-5-fluoro-alpha-L-idopyranose, CALCIUM ION, ... | | 著者 | Li, C, Zhang, R, Withers, S.G, Brayer, G.D. | | 登録日 | 2009-08-03 | | 公開日 | 2009-10-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase
Biochemistry, 48, 2009
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4HOX
 | | The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 in complex with Tris | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | | 登録日 | 2012-10-23 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 in complex with Tris
to be published
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1PJ9
 | | Bacillus circulans strain 251 loop mutant 183-195 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, CALCIUM ION, ... | | 著者 | Rozeboom, H.J, Dijkstra, B.W. | | 登録日 | 2003-06-02 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Improved thermostability of bacillus circulans cyclodextrin glycosyltransferase by the introduction of a salt bridge
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
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4HOZ
 | | The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5 in complex with D-glucose | | 分子名称: | CALCIUM ION, GLYCEROL, Sucrose isomerase, ... | | 著者 | Xu, Z, Li, S, Xu, H, Zhou, J. | | 登録日 | 2012-10-23 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Structural Basis of Erwinia rhapontici Isomaltulose Synthase
Plos One, 8, 2013
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1XCW
 | | Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-amylase, ... | | 著者 | Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D. | | 登録日 | 2004-09-03 | | 公開日 | 2004-12-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
Biochemistry, 44, 2005
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1XD0
 | | Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, Alpha-amylase, ... | | 著者 | Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D. | | 登録日 | 2004-09-03 | | 公開日 | 2004-12-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
Biochemistry, 44, 2005
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1XGZ
 | | Structure of the N298S variant of human pancreatic alpha-amylase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, pancreatic, ... | | 著者 | Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D. | | 登録日 | 2004-09-17 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase
PROTEIN SCI., 14, 2005
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