PDB: 523 件ウェブページステータス検索Chemie searchBIRD

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4HVV	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide APP12 分子名称: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, SYNTHETIC PEPTIDE Acetyl-APPLPPRNRP 著者 Camara-Artigas, A. 登録日 2012-11-07 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
4HVU	Crystal structure of the T98D c-Src-SH3 domain mutant in complex with the high affinity peptide APP12 分子名称: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... 著者 Camara-Artigas, A. 登録日 2012-11-07 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
4HVW	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide VSL12 分子名称: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... 著者 Camara-Artigas, A. 登録日 2012-11-07 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
2LZ6	Distinct ubiquitin binding modes exhibited by sh3 domains: molecular determinants and functional implications 分子名称: CD2-associated protein, Ubiquitin 著者 Ortega-Roldan, J, Azuaga, A, Blackledge, M, Van Nuland, N. 登録日 2012-09-24 公開日 2013-10-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Distinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional Implications. Plos One, 8, 2013
4GLM	Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens] 分子名称: Dynamin-binding protein, UNKNOWN ATOM OR ION 著者 Dong, A, Guan, X, Huang, H, Tempel, W, Gu, J, Sidhu, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2012-08-14 公開日 2012-11-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the SH3 Domain of DNMBP protein [Homo sapiens] to be published
4FSS	Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution 分子名称: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-06-27 公開日 2012-07-18 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution To be published
4F16	Crystal Structure of the alpha spectrin SH3 domain at pH 5 分子名称: Spectrin alpha chain, brain 著者 Camara-Artigas, A, Gavira, J.A. 登録日 2012-05-06 公開日 2013-05-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystal Structure of the alpha spectrin SH3 domain at pH 5 To be Published
4F17	Crystal Structure of the alpha spectrin SH3 domain at pH 9 分子名称: Spectrin alpha chain, brain 著者 Camara-Artigas, A, Gavira, J.A. 登録日 2012-05-06 公開日 2013-05-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of the alpha spectrin SH3 domain at pH 9 To be Published
4ESR	Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors 分子名称: DI(HYDROXYETHYL)ETHER, Jouberin 著者 Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X. 登録日 2012-04-23 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors. Proteomics, 12, 2012
3VRY	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane 分子名称: 4-Amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl-cyclopentane, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Niwa, H, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.481 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS7	Crystal structure of HCK complexed with a pyrazolo-pyrimidine inhibitor 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 分子名称: 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Honda, K, Niwa, H, Toyama, M, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VRZ	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea 分子名称: 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.218 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS1	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea 分子名称: 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-phenylurea, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Toyama, M, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.464 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS4	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 5-(4-phenoxyphenyl)-7-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 分子名称: 5-(4-phenoxyphenyl)-7-(tetrahydro-2H-pyran-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.747 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS3	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 分子名称: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomaebchi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS0	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor N-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]benzamide 分子名称: CALCIUM ION, CHLORIDE ION, N-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]benzamide, ... 著者 Kuratani, M, Honda, K, Tomabechi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.934 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS6	Crystal structure of HCK complexed with a pyrazolo-pyrimidine inhibitor tert-butyl {4-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl}carbamate 分子名称: CALCIUM ION, CHLORIDE ION, Tyrosine-protein kinase HCK, ... 著者 Kuratani, M, Honda, K, Tomabechi, Y, Toyama, M, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.373 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS5	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 分子名称: 7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, Tyrosine-protein kinase HCK 著者 Kuratani, M, Tomabechi, Y, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
3VS2	Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 分子名称: 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Kuratani, M, Tomabechi, Y, Niwa, H, Parker, J.L, Handa, N, Yokoyama, S. 登録日 2012-04-21 公開日 2013-05-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.609 Å) 主引用文献 A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo Sci Transl Med, 5, 2013
4EIK	Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12 分子名称: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide 著者 Camara-Artigas, A. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex. Acta Crystallogr F Struct Biol Commun, 72, 2016
2LQW	Solution structure of phosphorylated CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-16 公開日 2012-05-16 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LQN	Solution structure of CRKL 分子名称: Crk-like protein 著者 Jankowski, W, Saleh, T, Kalodimos, C. 登録日 2012-03-09 公開日 2012-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat.Chem.Biol., 8, 2012
2LP5	Native Structure of the Fyn SH3 A39V/N53P/V55L 分子名称: Tyrosine-protein kinase Fyn 著者 Neudecker, P, Robustelli, P, Cavalli, A, Vendruscolo, M, Kay, L.E. 登録日 2012-02-06 公開日 2012-05-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of an intermediate state in protein folding and aggregation. Science, 336, 2012
4D8D	Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant 分子名称: GLYCEROL, Protein Nef, Tyrosine-protein kinase Fyn 著者 Arold, S.T, Hoh, F, Dumas, C. 登録日 2012-01-10 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5201 Å) 主引用文献 Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
4D8K	Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution 分子名称: GLYCEROL, SULFATE ION, Tyrosine-protein kinase Lck 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2012-01-10 公開日 2012-01-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal structure of a SH3-SH2 domains of a lymphocyte-specific protein tyrosine kinase (LCK) from Homo sapiens at 2.36 A resolution To be published

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