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2QEW
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Rat cytosolic PEPCK, in complex with manganese ion.
分子名称: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ...
著者Sullivan, S.M, Holyoak, T.
登録日2007-06-26
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2QEY
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BU of 2qey by Molmil
Rat cytosolic PEPCK in complex with GTP
分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Sullivan, S.M, Holyoak, T.
登録日2007-06-26
公開日2007-08-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid.
Biochemistry, 46, 2007
2GMV
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PEPCK complex with a GTP-competitive inhibitor
分子名称: MANGANESE (II) ION, N-(4-{[3-BUTYL-1-(2-FLUOROBENZYL)-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL]METHYL}PHENYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE, PHOSPHOENOLPYRUVATE, ...
著者Dunten, P.
登録日2006-04-07
公開日2007-05-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase.
Bioorg.Med.Chem.Lett., 17, 2007
2ISI
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BU of 2isi by Molmil
Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand
分子名称: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION, PHOSPHATE ION
著者Agarwal, R, Naidu, M.D.
登録日2006-10-17
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Crystal structure of hApe1 in a new crystal form with a bound ligand: implications on catalytic mechanism and its inhibition
To be Published
1YNW
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Crystal Structure of Vitamin D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element
分子名称: 5'-d(*TP*TP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*AP*A)-3', 5'-d(*TP*TP*TP*GP*AP*CP*CP*TP*TP*CP*GP*TP*GP*AP*CP*CP*TP*A)-3', Retinoic acid receptor RXR-alpha, ...
著者Shaffer, P.L, Gewirth, D.T.
登録日2005-01-25
公開日2005-02-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of RXR-VDR interactions on DR3 DNA
J.Steroid Biochem.Mol.Biol., 89-90, 2004
1R0N
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BU of 1r0n by Molmil
Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex
分子名称: Ecdsyone Response Element, Ecdysone Response Element, Ecdysone receptor, ...
著者Devarakonda, S, Harp, J.M, Kim, Y, Ozyhar, A, Rastinejad, F.
登録日2003-09-22
公開日2003-10-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the heterodimeric Ecdysone Receptor DNA-binding complex
Embo J., 22, 2003
1M51
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PEPCK complex with a GTP-competitive inhibitor
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
著者Foley, L.H, Wang, P, Dunten, P, Wertheimer, S.J.
登録日2002-07-06
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献X-ray Structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines
Bioorg.Med.Chem.Lett., 13, 2003
1NHX
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PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR
分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, N-{4-[1-(2-FLUOROBENZYL)-3-BUTYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YLMETHYL]-PHENYL}-ACETAMIDE, ...
著者Foley, L.H, Wang, P, Dunten, P, Ramsey, G, Gubler, M.-L, Wertheimer, S.J.
登録日2002-12-19
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines
Bioorg.Med.Chem.Lett., 13, 2003
1P4Q
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BU of 1p4q by Molmil
Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain
分子名称: Cbp/p300-interacting transactivator 2, E1A-associated protein p300, ZINC ION
著者Freedman, S.J, Sun, Z.-Y.J, Kung, A.L, France, D.S, Wagner, G, Eck, M.J.
登録日2003-04-23
公開日2003-07-01
最終更新日2017-02-01
実験手法SOLUTION NMR
主引用文献Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
Nat.Struct.Biol., 10, 2003
1JM4
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NMR Structure of P/CAF Bromodomain in Complex with HIV-1 Tat Peptide
分子名称: HIV-1 Tat Peptide, P300/CBP-associated Factor
著者Mujtaba, S, He, Y, Zeng, L, Farooq, A, Carlson, J.E, Ott, M, Verdin, E, Zhou, M.-M.
登録日2001-07-17
公開日2002-07-17
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
Mol.Cell, 9, 2002
1K5K
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Homonuclear 1H Nuclear Magnetic Resonance Assignment and Structural Characterization of HIV-1 Tat Mal Protein
分子名称: TAT protein
著者Gregoire, C, Peloponese, J.M, Esquieu, D, Opi, S, Campbell, G, Solomiac, M, Lebrun, E, Lebreton, J, Loret, E.P.
登録日2001-10-11
公開日2002-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein.
Biopolymers, 62, 2001
1L3E
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NMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex
分子名称: ZINC ION, hypoxia inducible factor-1 alpha subunit, p300 protein
著者Freedman, S.J, Sun, Z.J, Poy, F, Kung, A.L, Livingston, D.M, Wagner, G, Eck, M.J.
登録日2002-02-26
公開日2002-04-24
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KHE
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PEPCK complex with nonhydrolyzable GTP analog, MAD data
分子名称: MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Phosphoenolpyruvate Carboxykinase, ...
著者Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J.
登録日2001-11-29
公開日2002-02-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHG
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PEPCK
分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ...
著者Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J.
登録日2001-11-29
公開日2002-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHF
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PEPCK complex with PEP
分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
著者Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J.
登録日2001-11-29
公開日2002-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHB
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PEPCK complex with nonhydrolyzable GTP analog, native data
分子名称: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
著者Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J.
登録日2001-11-29
公開日2002-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1JFW
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HOMONUCLEAR AND HETERONUCLEAR 1H-13C NUCLEAR MAGNETIC RESONANCE ASSIGNMENT AND STRUCTURAL CHARACTERIZATION OF A HIV-1 TAT PROTEIN
分子名称: TAT PROTEIN
著者Peloponese, J.M, Gregoire, C, Opi, S, Esquieu, D.
登録日2001-06-22
公開日2001-08-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献1H-13C nuclear magnetic resonance assignment and structural characterization of HIV-1 Tat protein.
C.R.Acad.Sci.III, 323, 2000
1HD7
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A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism
分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
著者Beernink, P.T, Segelke, B.W, Rupp, B.
登録日2000-11-09
公開日2001-02-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1E9N
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A second divalent metal ion in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1, and its implications for the catalytic mechanism
分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION
著者Beernink, P.T, Segelke, B.W, Rupp, B.
登録日2000-10-24
公開日2001-02-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism
J.Mol.Biol., 307, 2001
1DSZ
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STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
分子名称: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ...
著者Rastinejad, F, Wagner, T, Zhao, Q, Khorasanizadeh, S.
登録日2000-01-10
公開日2000-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
EMBO J., 19, 2000
1BY4
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BU of 1by4 by Molmil
STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA
分子名称: DNA (5'-D(*C*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*A)-3'), PROTEIN (RETINOIC ACID RECEPTOR RXR-ALPHA), ...
著者Zhao, Q, Chasse, S.A, Devarakonda, S, Sierk, M.L, Ahvazi, B, Sigler, P.B, Rastinejad, F.
登録日1998-10-22
公開日2000-01-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of RXR-DNA interactions.
J.Mol.Biol., 296, 2000
1GNF
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SOLUTION STRUCTURE OF THE N-TERMINAL ZINC FINGER OF MURINE GATA-1, NMR, 25 STRUCTURES
分子名称: TRANSCRIPTION FACTOR GATA-1, ZINC ION
著者Kowalski, K, Czolij, R, King, G.F, Crossley, M, Mackay, J.P.
登録日1998-10-12
公開日1999-06-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG.
J.Biomol.NMR, 13, 1999
1TBC
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HIV-1 TAT, NMR, 10 STRUCTURES
分子名称: TAT PROTEIN
著者Roesch, P, Boehm, M, Sticht, H.
登録日1998-03-13
公開日1999-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of HIV-1 Tat Protein
To be Published
1TAC
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HIV-1 TAT CYS-, NMR, 10 STRUCTURES
分子名称: TAT PROTEIN
著者Roesch, P, Boehm, M, Sticht, H.
登録日1998-03-13
公開日1999-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of HIV-1 Tat Protein
To be Published
1NFI
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I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX
分子名称: I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65
著者Jacobs, M.D, Harrison, S.C.
登録日1998-08-25
公開日1998-11-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of an IkappaBalpha/NF-kappaB complex.
Cell(Cambridge,Mass.), 95, 1998

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