PDB: 187313 件ウェブページステータス検索Chemie searchBIRD

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2O72	Crystal Structure Analysis of human E-cadherin (1-213) 分子名称: CALCIUM ION, Epithelial-cadherin 著者 Parisini, E, Wang, J.-H. 登録日 2006-12-09 公開日 2007-10-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism J.Mol.Biol., 373, 2007
5NO6	TEAD4-HOXB13 complex bound to DNA 分子名称: DNA, Homeobox protein Hox-B13, Transcriptional enhancer factor TEF-3 著者 Morgunova, E, Jolma, A, Yin, Y, Popov, A, Taipale, J. 登録日 2017-04-11 公開日 2018-05-16 最終更新日 2025-04-23 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 DNA-guided transcription factor interactions extend human gene regulatory code. Nature, 2025
1MBB	OXIDOREDUCTASE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-3(N-ACETYLGLUCOSAMINYL)BUTYRIC ACID 著者 Benson, T.E, Lees, W.J, Walsh, C.T, Hogle, J.M. 登録日 1995-11-07 公開日 1996-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 (E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Biochemistry, 35, 1996
4ZSW	Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid 分子名称: (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... 著者 Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. 登録日 2015-05-14 公開日 2015-07-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chem.Biol., 10, 2015
5AAU	Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist 分子名称: 3-(1-(4-Chlorophenyl)-3,4-dihydro-1H-pyrido(3,4-b)indol-2(9H)-yl)propanoic acid, ESTROGEN RECEPTOR 著者 Norman, R.A, Bradbury, R.H, de Almeida, C, Andrews, D.M, Ballard, P, Buttar, D, Callis, R.J, Currie, G.S, Curwen, J.O, Davies, C.D, de Savi, C, Donald, C.S, Feron, L.J.L, Glossop, S.C, Hayter, B.R, Karoutchi, G, Lamont, S.G, MacFaul, P, Moss, T, Pearson, S.E, Rabow, A.A, Tonge, M, Walker, G.E, Weir, H.M, Wilson, Z. 登録日 2015-07-28 公開日 2015-10-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2, 3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist. J.Med.Chem., 58, 2015
5AAV	Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist 分子名称: (2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID, ESTROGEN RECEPTOR 著者 Norman, R.A, Bradbury, R.H, de Almeida, C, Andrews, D.M, Ballard, P, Buttar, D, Callis, R.J, Currie, G.S, Curwen, J.O, Davies, C.D, de Savi, C, Donald, C.S, Feron, L.J.L, Glossop, S.C, Hayter, B.R, Karoutchi, G, Lamont, S.G, MacFaul, P, Moss, T, Pearson, S.E, Rabow, A.A, Tonge, M, Walker, G.E, Weir, H.M, Wilson, Z. 登録日 2015-07-29 公開日 2015-10-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2, 3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist. J.Med.Chem., 58, 2015
7YG6	Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA 分子名称: MAGNESIUM ION, Piwi, piRNA 著者 Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. 登録日 2022-07-11 公開日 2024-01-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
7YFX	Cryo-EM structure of Hili in complex with piRNA 分子名称: MAGNESIUM ION, Piwi-like protein 2, piRNA 著者 Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. 登録日 2022-07-09 公開日 2024-01-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
7YGN	Cryo-EM structure of the Mili in complex with piRNA 分子名称: MAGNESIUM ION, Piwi-like protein 2, piRNA 著者 Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. 登録日 2022-07-11 公開日 2024-01-24 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
9IJ0	Cryo-EM Structure of MILI-piRNA-target (8-nt) 分子名称: MAGNESIUM ION, Piwi-like protein 2, RNA (26-MER), ... 著者 Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. 登録日 2024-06-21 公開日 2024-11-13 最終更新日 2025-03-19 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into RNA cleavage by PIWI Argonaute. Nature, 639, 2025
1EZZ	CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE 分子名称: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION 著者 Jin, L, Stec, B, Kantrowitz, E.R. 登録日 2000-05-12 公開日 2000-11-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures. Biochemistry, 39, 2000
6HPB	Crystal structure of the E.coli HicAB toxin-antitoxin complex 分子名称: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA 著者 Manav, M.C, Brodersen, D.E. 登録日 2018-09-20 公開日 2019-09-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain. Structure, 27, 2019
4C16	E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist 分子名称: (1R,2R,3S)-3-methylcyclohexane-1,2-diol, (S)-CYCLOHEXYL LACTIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T. 登録日 2013-08-09 公開日 2014-08-20 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation. J.Mol.Cell.Biol., 8, 2016
1F1B	CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE R-STATE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ASPARTATE 分子名称: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... 著者 Jin, L, Stec, B, Kantrowitz, E.R. 登録日 2000-05-18 公開日 2000-11-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures. Biochemistry, 39, 2000
4L1T	Transthyretin in complex with (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzoic acid 分子名称: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin 著者 Connelly, S, Wilson, I.A. 登録日 2013-06-03 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn. Biopolymers, 101, 2014
4HR7	Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli 分子名称: 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ... 著者 Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L. 登録日 2012-10-26 公開日 2013-03-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.495 Å) 主引用文献 The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase. Structure, 21, 2013
7DFM	Crystal structure of glycoside hydrolase family 11 beta-xylanase from Streptomyces olivaceoviridis E-86 分子名称: CHLORIDE ION, Endo-1,4-beta-xylanase 著者 Fujimoto, Z, Kishine, N, Kaneko, S. 登録日 2020-11-09 公開日 2020-12-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based substrate specificity analysis of GH11 xylanase from Streptomyces olivaceoviridis E-86. Appl.Microbiol.Biotechnol., 105, 2021
7DFO	Crystal structure of glycoside hydrolase family 11 beta-xylanase from Streptomyces olivaceoviridis E-86 in complex with 4-O-methyl-alpha-D-glucuronopyranosyl xylotetraose 分子名称: 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, CHLORIDE ION, ... 著者 Fujimoto, Z, Kishine, N, Kaneko, S. 登録日 2020-11-09 公開日 2020-12-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based substrate specificity analysis of GH11 xylanase from Streptomyces olivaceoviridis E-86. Appl.Microbiol.Biotechnol., 105, 2021
3MPB	Z5688 from E. coli O157:H7 bound to fructose 分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 van Staalduinen, L.M, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2010-04-26 公開日 2010-07-21 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure-based annotation of a novel sugar isomerase from the pathogenic E. coli O157:H7. J.Mol.Biol., 401, 2010
3KMH	Crystal Structure of a Novel Sugar Isomerase from E. coli O157:H7 分子名称: ACETATE ION, D-lyxose isomerase, GLYCEROL, ... 著者 van Staalduinen, L.M, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2009-11-10 公開日 2010-07-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structure-based annotation of a novel sugar isomerase from the pathogenic E. coli O157:H7. J.Mol.Biol., 401, 2010
7JGJ	IgA1 Protease in complex with neutralizing mAb 分子名称: Immunoglobulin A1 protease, mAB Heavy Chain, mAB Light Chain 著者 Eisenmesser, E.Z, Zheng, H. 登録日 2020-07-19 公開日 2020-12-09 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease Nat Commun, 11, 2020
3TTQ	Crystal structure of Leuconostoc mesenteroides NRRL B-1299 N-terminally truncated dextransucrase DSR-E in orthorhombic apo-form at 1.9 angstrom resolution 分子名称: CALCIUM ION, Dextransucrase, GLYCEROL, ... 著者 Brison, Y, Pijning, T, Fabre, E, Mourey, L, Morel, S, Potocki-Veronese, G, Monsan, P, Remaud-Simeon, M, Dijkstra, B.W, Tranier, S. 登録日 2011-09-15 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Functional and structural characterization of alpha-(1-2) branching sucrase derived from DSR-E glucansucrase J.Biol.Chem., 287, 2012
1V6V	Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(2)-alpha-L-arabinofuranosyl-xylotriose 分子名称: ENDO-1,4-BETA-D-XYLANASE, alpha-L-arabinofuranose-(1-3)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ... 著者 Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. 登録日 2003-12-04 公開日 2004-04-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86 J.Biol.Chem., 279, 2004
1V6X	Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(3)-4-O-methyl-alpha-D-glucuronosyl-xylotriose 分子名称: 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ENDO-1,4-BETA-D-XYLANASE, beta-D-xylopyranose, ... 著者 Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. 登録日 2003-12-04 公開日 2004-04-27 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86 J.Biol.Chem., 279, 2004
1V6U	Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 2(2)-alpha-L-arabinofuranosyl-xylobiose 分子名称: alpha-D-xylopyranose, alpha-L-arabinofuranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ... 著者 Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. 登録日 2003-12-04 公開日 2004-04-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86 J.Biol.Chem., 279, 2004

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