6ZSO
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![BU of 6zso by Molmil](/molmil-images/mine/6zso) | Solution structure of the water-soluble LU-domain of human Lypd6b protein | 分子名称: | Ly6/PLAUR domain-containing protein 6B | 著者 | Tsarev, A.V, Kulbatskii, D.S, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O. | 登録日 | 2020-07-16 | 公開日 | 2021-01-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors. Int J Mol Sci, 21, 2020
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4UY2
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![BU of 4uy2 by Molmil](/molmil-images/mine/4uy2) | Crystal structure of the complex of the extracellular domain of human alpha9 nAChR with alpha-bungarotoxin. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-BUNGAROTOXIN ISOFORM V31, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 | 著者 | Giastas, P, Zouridakis, M, Zarkadas, E, Tzartos, S.J. | 登録日 | 2014-08-28 | 公開日 | 2014-10-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Crystal Structures of Free and Antagonist-Bound States of Human Alpha9 Nicotinic Receptor Extracellular Domain Nat.Struct.Mol.Biol., 21, 2014
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6ZFM
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![BU of 6zfm by Molmil](/molmil-images/mine/6zfm) | Structure of alpha-Cobratoxin with a peptide inhibitor | 分子名称: | 3-[2-[2-[2-[2-[2-(2-azanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propan-1-ol, Alpha-cobratoxin, PENTAETHYLENE GLYCOL, ... | 著者 | Kiontke, S, Kummel, D. | 登録日 | 2020-06-17 | 公開日 | 2020-12-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Peptide Inhibitors of the alpha-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction. J.Med.Chem., 63, 2020
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9BAF
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![BU of 9baf by Molmil](/molmil-images/mine/9baf) | Solution NMR structure of conofurin-Delta | 分子名称: | Alpha-conotoxin LvIA | 著者 | Harvey, P.J, Craik, D.J, Hone, A.J, McIntosh, J.M. | 登録日 | 2024-04-04 | 公開日 | 2024-07-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors. J.Med.Chem., 67, 2024
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6HY7
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![BU of 6hy7 by Molmil](/molmil-images/mine/6hy7) | |
6D9H
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![BU of 6d9h by Molmil](/molmil-images/mine/6d9h) | Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist | 分子名称: | ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Draper-Joyce, C.J, Khoshouei, M, Thal, D.M, Liang, Y.-L, Nguyen, A.T.N, Furness, S.G.B, Venugopal, H, Baltos, J, Plitzko, J.M, Danev, R, Baumeister, W, May, L.T, Wootten, D, Sexton, P, Glukhova, A, Christopoulos, A. | 登録日 | 2018-04-29 | 公開日 | 2018-06-20 | 最終更新日 | 2018-07-11 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the adenosine-bound human adenosine A1receptor-Gicomplex. Nature, 558, 2018
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1IM1
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![BU of 1im1 by Molmil](/molmil-images/mine/1im1) | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1, 20 STRUCTURES | 分子名称: | ALPHA-CONOTOXIN IM1 | 著者 | Rogers, J.P, Luginbuhl, P, Shen, G.S, Mccabe, R.T, Stevens, R.C, Wemmer, D.E. | 登録日 | 1998-11-18 | 公開日 | 1999-06-15 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry, 38, 1999
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5AIN
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![BU of 5ain by Molmil](/molmil-images/mine/5ain) | Varenicline Interactions at the 5HT3 Receptor Ligand Binding Site are Revealed by 5HTBP | 分子名称: | SOLUBLE ACETYLCHOLINE RECEPTOR, VARENICLINE | 著者 | Price, K.L, Lillestol, R, Ulens, C, Lummis, S.C. | 登録日 | 2015-02-16 | 公開日 | 2015-03-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Varenicline Interactions at the 5-Ht3 Receptor Ligand Binding Site are Revealed by 5-Htbp. Acs Chem Neurosci, 6, 2015
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2N99
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![BU of 2n99 by Molmil](/molmil-images/mine/2n99) | Solution structure of the SLURP-2, a secreted isoform of Lynx1 | 分子名称: | Ly-6/neurotoxin-like protein 1 | 著者 | Paramonov, A.S, Shenkarev, Z.O, Lyukmanova, E.N, Arseniev, A.S. | 登録日 | 2015-11-11 | 公開日 | 2016-09-21 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors. Sci Rep, 6, 2016
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1IMI
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![BU of 1imi by Molmil](/molmil-images/mine/1imi) | SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 | 分子名称: | PROTEIN (ALPHA-CONOTOXIN IMI) | 著者 | Maslennikov, I.V, Shenkarev, Z.O, Zhmak, M.N, Tsetlin, V.I, Ivanov, V.T, Arseniev, A.S. | 登録日 | 1998-11-27 | 公開日 | 1999-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR spatial structure of alpha-conotoxin ImI reveals a common scaffold in snail and snake toxins recognizing neuronal nicotinic acetylcholine receptors. FEBS Lett., 444, 1999
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6UR8
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![BU of 6ur8 by Molmil](/molmil-images/mine/6ur8) | CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimera of soluble cytochrome b562 (BRIL) and neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, ... | 著者 | Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A. | 登録日 | 2019-10-22 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nat Commun, 11, 2020
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6KN2
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1E74
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![BU of 1e74 by Molmil](/molmil-images/mine/1e74) | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E | 分子名称: | ALPHA-CONOTOXIN IM1(R11E) | 著者 | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | 登録日 | 2000-08-24 | 公開日 | 2000-12-27 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist J.Mol.Biol., 304, 2000
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1E76
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![BU of 1e76 by Molmil](/molmil-images/mine/1e76) | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N | 分子名称: | ALPHA-CONOTOXIN IM1(D5N) | 著者 | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | 登録日 | 2000-08-24 | 公開日 | 2000-12-27 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist J.Mol.Biol., 304, 2000
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1E75
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![BU of 1e75 by Molmil](/molmil-images/mine/1e75) | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R7L | 分子名称: | ALPHA-CONOTOXIN IM1(R7L) | 著者 | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | 登録日 | 2000-08-24 | 公開日 | 2000-12-27 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist J.Mol.Biol., 304, 2000
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4X9Z
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![BU of 4x9z by Molmil](/molmil-images/mine/4x9z) | Dimeric conotoxin alphaD-GeXXA | 分子名称: | alphaD-conotoxin GeXXA from the venom of Conus generalis | 著者 | Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C. | 登録日 | 2014-12-12 | 公開日 | 2015-12-02 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors Sci Rep, 5, 2015
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6IB6
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![BU of 6ib6 by Molmil](/molmil-images/mine/6ib6) | Solution structure of the water-soluble LU-domain of human Lypd6 protein | 分子名称: | Ly6/PLAUR domain-containing protein 6 | 著者 | Tsarev, A.V, Kulbatskii, D.S, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O. | 登録日 | 2018-11-29 | 公開日 | 2019-12-18 | 最終更新日 | 2021-01-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors. Int J Mol Sci, 21, 2020
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1M2C
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![BU of 1m2c by Molmil](/molmil-images/mine/1m2c) | THREE-DIMENSIONAL STRUCTURE OF ALPHA-CONOTOXIN MII, NMR, 14 STRUCTURES | 分子名称: | ALPHA-CONOTOXIN MII | 著者 | Shon, K.J, Koerber, S.C, Rivier, J.E, Olivera, B.M, Mcintosh, J.M. | 登録日 | 1997-09-15 | 公開日 | 1998-12-09 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors. J.Biol.Chem., 271, 1996
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6KNO
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![BU of 6kno by Molmil](/molmil-images/mine/6kno) | |
6KMY
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![BU of 6kmy by Molmil](/molmil-images/mine/6kmy) | |
6KNP
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6KN3
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7N1Z
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![BU of 7n1z by Molmil](/molmil-images/mine/7n1z) | NMR structure of native PnIA | 分子名称: | Alpha-conotoxin PnIA | 著者 | Conibear, A.C, Rosengren, K.J, Lee, H.S. | 登録日 | 2021-05-28 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Posttranslational modifications of alpha-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. Rsc Med Chem, 12, 2021
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7N21
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![BU of 7n21 by Molmil](/molmil-images/mine/7n21) | NMR structure of AnIB-OH | 分子名称: | Alpha-conotoxin AnIB | 著者 | Conibear, A.C, Rosengren, K.J, Lee, H.S. | 登録日 | 2021-05-28 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Posttranslational modifications of alpha-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. Rsc Med Chem, 12, 2021
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7N23
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![BU of 7n23 by Molmil](/molmil-images/mine/7n23) | |