PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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1ZQE	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CRCL3 (SATURATED SOLUTION) 分子名称: CHROMIUM ION, DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-12 公開日 1996-04-12 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
1ZQQ	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (15 MILLIMOLAR) AND NACL (15 MILLIMOLAR) 分子名称: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), MANGANESE (II) ION, ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-12 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
8AT0	PotF with mutation D247K 分子名称: (2R)-1-methoxypropan-2-amine, (2~{S})-1-(2-methoxyethoxy)propan-2-amine, 1,2-ETHANEDIOL, ... 著者 Kroeger, P, Shanmugaratnam, S, Hocker, B. 登録日 2022-08-22 公開日 2024-03-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A fluorescent biosensor for the visualization of Agmatine To Be Published
8AXD	Human serotonin 5-HT3A receptor (apo, resting conformation) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A 著者 Lopez-Sanchez, U, Nury, H. 登録日 2022-08-31 公開日 2024-03-06 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors. Nat.Struct.Mol.Biol., 31, 2024
8ADD	Viral tegument-like DUBs 分子名称: ATP-dependent DNA helicase 著者 Erven, I, Abraham, E.T, Hermanns, T, Hofmann, K, Baumann, U. 登録日 2022-07-08 公開日 2023-02-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
6YBS	Structure of a human 48S translational initiation complex - head 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... 著者 Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. 登録日 2020-03-17 公開日 2020-09-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of a human 48Stranslational initiation complex. Science, 369, 2020
8BPW	Crystal structure of JAK2 JH1 in complex with lestaurtinib 分子名称: Lestaurtinib, Tyrosine-protein kinase JAK2 著者 Miao, Y, Haikarainen, T. 登録日 2022-11-18 公開日 2023-11-29 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity. J.Med.Chem., 67, 2024
8BOT	Cryo-EM structure of NHEJ supercomplex(trimer) 分子名称: DNA (24-MER), DNA (27-MER), DNA (28-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-11-15 公開日 2023-06-28 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (7.76 Å) 主引用文献 Cryo-EM structure of a DNA-PK trimer: higher order oligomerisation in NHEJ. Structure, 31, 2023
6MBV	Carbonic Anhydrase II in complex with Nicotinic Acid 分子名称: Carbonic anhydrase 2, GLYCEROL, NICOTINIC ACID, ... 著者 Lomelino, C.L, McKenna, R. 登録日 2018-08-30 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.695 Å) 主引用文献 Carbonic anhydrase II in complex with carboxylic acid-based inhibitors. Acta Crystallogr F Struct Biol Commun, 75, 2019
3SSU	Crystal structure of vimentin coil1A/1B fragment 分子名称: Vimentin 著者 Nicolet, S, Chernyatina, A.A, Strelkov, S.V. 登録日 2011-07-08 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly. Proc.Natl.Acad.Sci.USA, 109, 2012
3DVD	X-ray crystal structure of mutant N62D of human Carbonic Anhydrase II 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Avvaru, B.S. 登録日 2008-07-18 公開日 2008-11-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II. Biochemistry, 47, 2008
1ZWD	STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 3-37, NMR, 10 STRUCTURES 分子名称: PARATHYROID HORMONE 著者 Roesch, P, Marx, U.C. 登録日 1996-06-17 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure-activity relation of NH2-terminal human parathyroid hormone fragments. J.Biol.Chem., 273, 1998
6YKK	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 15 分子名称: 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, Strelkov, S.V, Weeks, S.D. 登録日 2020-04-06 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.236 Å) 主引用文献 Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
6B4D	Crystal structure of human carbonic anhydrase II in complex with a heteroaryl-pyrazole carboxylic acid derivative. 分子名称: 3-(1-ethyl-1H-indol-3-yl)-1-methyl-1H-pyrazole-5-carboxylic acid, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Lomelino, C.L, Mahon, B.P, McKenna, R. 登録日 2017-09-26 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.196 Å) 主引用文献 Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors. ACS Med Chem Lett, 8, 2017
6YKV	Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11g 分子名称: 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... 著者 Pang, L, Strelkov, S.V, Weeks, S.D. 登録日 2020-04-06 公開日 2020-12-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors. Eur.J.Med.Chem., 211, 2021
8B55	Human ADGRG4 PTX-like domain 分子名称: Adhesion G-protein coupled receptor G4, MAGNESIUM ION 著者 Kieslich, B, Straeter, N. 登録日 2022-09-21 公開日 2022-10-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces. J.Biol.Chem., 299, 2023
8B1N	Crystal structure of TrmD-Tm1570 from Calditerrivibrio nitroreducens in complex with S-adenosyl-L-methionine 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Kluza, A, Lewandowska, I, Augustyniak, R, Sulkowska, J. 登録日 2022-09-10 公開日 2022-09-28 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Are there double knots in proteins? Prediction and in vitro verification based on TrmD-Tm1570 fusion from C. nitroreducens. Front Mol Biosci, 10, 2023
6B4O	1.73 Angstrom Resolution Crystal Structure of Glutathione Reductase from Enterococcus faecalis in Complex with FAD 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, ... 著者 Minasov, G, Warwzak, Z, Shuvalova, L, Dubrovska, I, Cardona-Correa, A, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-09-27 公開日 2017-10-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 1.73 Angstrom Resolution Crystal Structure of Glutathione Reductase from Enterococcus faecalis in Complex with FAD. To Be Published
3DH9	Crystal Structure of Drosophila Thioredoxin Reductase, wild-type 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase 1 著者 Eckenroth, B.E, Hondal, R.J, Everse, S.J. 登録日 2008-06-17 公開日 2009-06-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Drosophila Thioredoxin Reductase, wild-type To be Published
6YMA	MicroED structure of acetazolamide-bound human carbonic anhydrase II 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, DIMETHYL SULFOXIDE, ZINC ION, ... 著者 Clabbers, M.T.B, Fisher, S.Z, Coincon, M, Zou, X, Xu, H. 登録日 2020-04-08 公開日 2020-08-12 最終更新日 2024-01-24 実験手法 ELECTRON CRYSTALLOGRAPHY (2.5 Å) 主引用文献 Visualizing drug binding interactions using microcrystal electron diffraction. Commun Biol, 3, 2020
8B1V	Dihydroprecondylocarpine acetate synthase 2 from Tabernanthe iboga 分子名称: Dihydroprecondylocarpine acetate synthase 2, ZINC ION, precondylocarpine acetate 著者 Langley, C, Basquin, J, Caputi, L, O'Connor, S.E. 登録日 2022-09-12 公開日 2022-10-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.882 Å) 主引用文献 Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism. Angew.Chem.Int.Ed.Engl., 61, 2022
8B25	Dihydroprecondylocarpine acetate synthase 2 from Tabernanthe iboga - stemmadenine acetate bound structure 分子名称: 1,2-ETHANEDIOL, Dihydroprecondylocarpine acetate synthase 2, SULFATE ION, ... 著者 Langley, C, Basquin, J, Caputi, L, O'Connor, S.E. 登録日 2022-09-13 公開日 2022-10-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Expansion of the Catalytic Repertoire of Alcohol Dehydrogenases in Plant Metabolism. Angew.Chem.Int.Ed.Engl., 61, 2022
3SZ7	Crystal structure of the Sgt2 TPR domain from Aspergillus fumigatus 分子名称: Hsc70 cochaperone (SGT) 著者 Chartron, J.W, Gonzalez, G.M, Clemons Jr, W.M. 登録日 2011-07-18 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 A structural model of the Sgt2 protein and its interactions with chaperones and the Get4/Get5 complex. J.Biol.Chem., 286, 2011
6YO2	Meta-Carborane propyl-sulfonamide in complex with CA IX mimic 分子名称: Carbonic anhydrase 2, Meta-Carborane propyl-sulfonamide, ZINC ION 著者 Kugler, M, Brynda, J, Pospisilova, K, Rezacova, P. 登録日 2020-04-14 公開日 2020-08-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme. Chemistry, 26, 2020
4AGE	MTSSL spin labeled D67C mutant of MscS in the open form 分子名称: SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL 著者 Pliotas, C, Brannigan, E, Naismith, J.H. 登録日 2012-01-26 公開日 2012-08-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.84 Å) 主引用文献 Conformational State of the Mscs Mechanosensitive Channel in Solution Revealed by Pulsed Electron-Electron Double Resonance (Peldor) Spectroscopy. Proc.Natl.Acad.Sci.USA, 109, 2012

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