8BPW

Crystal structure of JAK2 JH1 in complex with lestaurtinib

Summary for 8BPW

• Entry DOI: 10.2210/pdb8bpw/pdb
• Descriptor: Tyrosine-protein kinase JAK2, Lestaurtinib (3 entities in total)
• Functional Keywords: janus kinase, inhibitor complex, jak2, jh1, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 75529.60

Authors

Miao, Y.,Haikarainen, T. (deposition date: 2022-11-18, release date: 2023-11-29)

• Primary citation: Miao, Y.,Silvennoinen, O.,Haikarainen, T.; Structural basis for JAK2 inhibition by clinical stage inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)