PDB: 47038 件ウェブページステータス検索Chemie searchBIRD

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1J1U	Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine 分子名称: MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ... 著者 Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-12-17 公開日 2003-06-03 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion NAT.STRUCT.BIOL., 10, 2003
7SP0	Crystal structure of human SFPQ L534I mutant in complex with zinc 分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION 著者 Lee, M. 登録日 2021-11-01 公開日 2022-10-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons. Open Biology, 12, 2022
7R3J	Nativ complex of PqsE and RhlR with the synthetic antagonist mBTL 分子名称: 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION, ... 著者 Borgert, S.R, Schmelz, S, Blankenfeldt, W. 登録日 2022-02-07 公開日 2022-12-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
7R3H	PROSS optimitzed variant of RhlR (75 mutations) in complex with native autoinducer C4-HSL 分子名称: N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, PROSS optimized variant of RhlR with 75 mutations 著者 Henke, S, Blankenfeldt, W. 登録日 2022-02-07 公開日 2022-12-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.49 Å) 主引用文献 Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
7R3E	Fusion construct of PqsE and RhlR in complex with the synthetic antagonist mBTL 分子名称: 2-aminobenzoylacetyl-CoA thioesterase,Regulatory protein RhlR, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION 著者 Borgert, S.R, Schmelz, S, Blankenfeldt, W. 登録日 2022-02-07 公開日 2022-12-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
7R3G	PROSS optimitzed variant of RhlR (75 mutations) in complex with the synthetic antagonist mBTL 分子名称: 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, Regulatory protein RhlR 著者 Henke, S, Blankenfeldt, W. 登録日 2022-02-07 公開日 2022-12-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
7R3I	PROSS optimitzed variant of RhlR (61 mutations) in complex with the synthetic antagonist mBTL 分子名称: 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, PROSS optimized variant of RhlR with 61 mutations 著者 Henke, S, Blankenfeldt, W. 登録日 2022-02-07 公開日 2022-12-14 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
8XSX	Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
1Q05	Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator 分子名称: COPPER (I) ION, Transcriptional regulator cueR 著者 Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. 登録日 2003-07-15 公開日 2003-09-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR Science, 301, 2003
1Q06	Crystal structure of the Ag(I) form of E. coli CueR, a copper efflux regulator 分子名称: SILVER ION, Transcriptional regulator cueR 著者 Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. 登録日 2003-07-15 公開日 2003-09-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR Science, 301, 2003
7AZS	70S thermus thermophilus ribosome with bound antibiotic lead SEQ-569 分子名称: (2R,3S,4R,5R,7S,9S,10S,11R,12S,13R)-12-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2-((S)-1-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-10-(((2S,3R,6R,E)-3-hydroxy-4-(methoxyimino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-7-(((2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl)carbamoyl)oxy)-6,14-dioxooxacyclotetradecan-4-yl 3-methylbutanoate, 16S rRNA, 23S rRNA, ... 著者 Jenner, L.B, Yusupov, M, Yusupova, G, Rak, A. 登録日 2020-11-17 公開日 2022-06-08 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
3UM3	Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP4B 分子名称: BRO1 domain-containing protein BROX, Charged multivesicular body protein 4b 著者 Jiang, J.S, Mu, R.L, Xiao, T. 登録日 2011-11-12 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B. Structure, 20, 2012
7AZO	70S thermus thermophilus ribosome with bound antibiotic lead SEQ-977 分子名称: (2R,3S,4R,5R,7S,9S,10S,11R,12S,13R)-12-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2-((S)-1-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-10-(((2S,3R,4R,6R)-3-hydroxy-4-(methoxyamino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-7-(((2-((2-nitrophenyl)sulfonamido)ethyl)carbamoyl)oxy)-6,14-dioxooxacyclotetradecan-4-yl 3-methylbutanoate, 16S rRNA, 23S rRNA, ... 著者 Jenner, L.B, Yusupov, M, Yusupova, G. 登録日 2020-11-17 公開日 2022-06-01 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 186, 2023
3UR1	The structure of a ternary complex between CheA domains P4 and P5 with CheW and with a truncated fragment of TM14, a chemoreceptor analog from Thermotoga maritima. 分子名称: Chemotaxis protein CheA, Chemotaxis protein CheW, Methyl-accepting chemotaxis protein 著者 Li, X, Crane, B.R, Bilwes, A.M. 登録日 2011-11-21 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 The structure of native bacterial chemoreceptor arrays Proc.Natl.Acad.Sci.USA, 2012
6CZ2	Structure of the PTK6 kinase domain 分子名称: Protein-tyrosine kinase 6 著者 Gajiwala, K.S, Johnson, E, Cronin, C.N. 登録日 2018-04-07 公開日 2018-06-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers. PLoS ONE, 13, 2018
3UR2	Crystal Structure of PTE mutant H254G/H257W/L303T/K185R/I274N/A80V 分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, IMIDAZOLE, ... 著者 Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. 登録日 2011-11-21 公開日 2012-08-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012
3UVN	Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1A 分子名称: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5 著者 Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F. 登録日 2011-11-30 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.792 Å) 主引用文献 The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases. Nucleic Acids Res., 40, 2012
6CKX	Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide 分子名称: Cyclin-K, Cyclin-dependent kinase 12, MAGNESIUM ION, ... 著者 Klein, M.G. 登録日 2018-03-01 公開日 2018-08-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors. J. Med. Chem., 61, 2018
8RKO	Bacteriophage JBD30 empty particle capsid 分子名称: Bacteriophage Mu GpT domain-containing protein 著者 Valentova, L, Fuzik, T, Plevka, P. 登録日 2023-12-27 公開日 2024-08-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Structure and replication of Pseudomonas aeruginosa phage JBD30. Embo J., 43, 2024
3UKM	Crystal structure of the human two pore domain potassium ion channel K2P1 (TWIK-1) 分子名称: POTASSIUM ION, Potassium channel subfamily K member 1, UNDECANE 著者 Long, S.B, Miller, A.N. 登録日 2011-11-09 公開日 2012-02-08 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal structure of the human two-pore domain potassium channel K2P1. Science, 335, 2012
8RKA	Connector complex of empty bacteriophage JBD30 particle computed in C12 symmetry 分子名称: DUF1320 domain-containing protein, Portal protein 著者 Valentova, L, Fuzik, T, Plevka, P. 登録日 2023-12-23 公開日 2024-08-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structure and replication of Pseudomonas aeruginosa phage JBD30. Embo J., 43, 2024
8RKN	Bacteriophage JBD30 capsid 分子名称: Bacteriophage Mu GpT domain-containing protein 著者 Valentova, L, Fuzik, T, Plevka, P. 登録日 2023-12-27 公開日 2024-08-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.57 Å) 主引用文献 Structure and replication of Pseudomonas aeruginosa phage JBD30. Embo J., 43, 2024
8RK8	Tail of bacteriophage JBD30 computed in C6 symmetry 分子名称: Major tail protein 著者 Valentova, L, Fuzik, T, Plevka, P. 登録日 2023-12-23 公開日 2024-08-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Structure and replication of Pseudomonas aeruginosa phage JBD30. Embo J., 43, 2024
8RK9	Stopper protein of bacteriophage JBD30 computed in C6 symmetry 分子名称: Stopper protein 著者 Valentova, L, Fuzik, T, Plevka, P. 登録日 2023-12-23 公開日 2024-08-14 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.95 Å) 主引用文献 Structure and replication of Pseudomonas aeruginosa phage JBD30. Embo J., 43, 2024
3UR5	Crystal Structure of PTE mutant K185R/I274N 分子名称: COBALT (II) ION, DIETHYL HYDROGEN PHOSPHATE, Parathion hydrolase 著者 Tsai, P, Fox, N.G, Li, Y, Barondeau, D.P, Raushel, F.M. 登録日 2011-11-21 公開日 2012-08-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Enzymes for the homeland defense: optimizing phosphotriesterase for the hydrolysis of organophosphate nerve agents. Biochemistry, 51, 2012

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