PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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8AK6	Human Sirt6 in complex with ADP-ribose and fragment sulfamethoxazole 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AK9	Human Sirt6 in complex with ADP-ribose and fragment Isatin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
1YNP	aldo-keto reductase AKR11C1 from Bacillus halodurans (apo form) 分子名称: GLYCEROL, SODIUM ION, SULFATE ION, ... 著者 Marquardt, T, Kostrewa, D, Winkler, F.K, Li, X.D. 登録日 2005-01-25 公開日 2005-12-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase J.Mol.Biol., 354, 2005
8AK7	Human Sirt6 in complex with ADP-ribose and fragment 6-O-methylguanine 分子名称: 1,2-ETHANEDIOL, 6-O-methylguanine, CHLORIDE ION, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AKA	Human Sirt6 in complex with ADP-ribose and fragment cis-resveratrol 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AKE	Human Sirt6 in complex with ADP-ribose and fragment nicotinamide 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AK8	Human Sirt6 in complex with ADP-ribose and fragment 4-hydroxybenzamide 分子名称: 4-HYDROXYBENZAMIDE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AKG	Human Sirt6 in complex with ADP-ribose and fragment 4-amino-6-chlorobenzene-1,3-disulfonamide 分子名称: 1,2-ETHANEDIOL, 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, CHLORIDE ION, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
6VM4	Chloroplast ATP synthase (C2, CF1FO) 分子名称: ATP synthase delta chain, chloroplastic, ATP synthase epsilon chain, ... 著者 Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. 登録日 2020-01-27 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (7.08 Å) 主引用文献 Structural basis of redox modulation on chloroplast ATP synthase. Commun Biol, 3, 2020
1XIO	Anabaena sensory rhodopsin 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ANABAENA SENSORY RHODOPSIN, RETINAL 著者 Vogeley, L, Luecke, H. 登録日 2004-09-21 公開日 2004-10-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A. Science, 306, 2004
8EV1	Dual Modulators 分子名称: (3aR,4S,9bS)-4-(4-hydroxyphenyl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[c]quinoline-8-sulfonamide, (3aS,4R,9bR)-4-(4-hydroxyphenyl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[c]quinoline-8-sulfonamide, Estrogen Receptor, ... 著者 Tinivella, A, Nwachukwu, J.C, Angeli, A, Foschi, F, Benatti, A.L, Pinzi, L, Izard, T, Ferraroni, M, Rangarajan, E.S, Christodoulou, M, Passarella, D, Supuran, C, Nettles, K.W, Rastelli, G. 登録日 2022-10-19 公開日 2022-12-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors. Eur.J.Med.Chem., 246, 2022
8B5T	Crystal structure of Quinonoid dihydropteridine reductase from Leishmania major 分子名称: Quinonoid dihydropteridine reductase 著者 Robinson, D.A, Fairlamb, A.H. 登録日 2022-09-24 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Quinonoid dihydropteridine reductase from Leishmania major To Be Published
8A71	Crystal structure of right-handed Z-DNA containing 2'-deoxy-L-ribose in complex with the polyamine cadaverine and potassium cations at ultrahigh resolution 分子名称: 5-azaniumylpentylazanium, POTASSIUM ION, Right-handed Z-DNA 著者 Drozdzal, P, Manszewski, T, Gilski, M, Brzezinski, K, Jaskolski, M. 登録日 2022-06-20 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (0.69 Å) 主引用文献 Right-handed Z-DNA at ultrahigh resolution: a tale of two hands and the power of the crystallographic method. Acta Crystallogr D Struct Biol, 79, 2023
8FC1	Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.50A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
8B8A	Multimerization domain of borna disease virus 1 phosphoprotein 分子名称: Phosphoprotein 著者 Tarbouriech, N, Legrand, P, Bourhis, J.M, Chenavier, F, Freslon, L, Kawasaki, J, Horie, M, Tomonaga, K, Bachiri, K, Coyaud, E, Gonzalez-Dunia, D, Ruigrok, R.W.H, Crepin, T. 登録日 2022-10-04 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing. Viruses, 14, 2022
8BGC	Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with compound 2 (AA-CS-9-003) 分子名称: 5-[(phenylmethyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION 著者 Kraemer, A, Axtman, A.D, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2022-10-27 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2. Acs Med.Chem.Lett., 14, 2023
8BAD	Tpp80Aa1 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Binary toxin A-like protein, CALCIUM ION, ... 著者 Best, H.L, Williamson, L.J, Rizkallah, P.J, Berry, C, Lloyd-Evans, E. 登録日 2022-10-11 公開日 2022-12-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 The Crystal Structure of Bacillus thuringiensis Tpp80Aa1 and Its Interaction with Galactose-Containing Glycolipids. Toxins, 14, 2022
2ZEB	Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase 分子名称: 1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine, Tryptase beta 2 著者 Spurlino, J.C, Lewandowski, F, Milligan, C. 登録日 2007-12-08 公開日 2008-12-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives Bioorg.Med.Chem.Lett., 18, 2008
1XPL	Crystal Structure of Staphylococcus aureus HMG-COA Synthase with Acetoacetyl-COA and Acetylated Cysteine 分子名称: 3-hydroxy-3-methylglutaryl CoA synthase, ACETOACETYL-COENZYME A, SULFATE ION 著者 Theisen, M.J, Misra, I, Saadat, D, Campobasso, N, Miziorko, H.M, Harrison, D.H.T. 登録日 2004-10-08 公開日 2004-11-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 3-hydroxy-3-methylglutaryl-CoA synthase intermediate complex observed in "real-time" Proc.Natl.Acad.Sci.USA, 47, 2004
8AHQ	VirD/holo-ACP5b of Streptomyces virginiae complex 分子名称: 1,2-ETHANEDIOL, 4'-PHOSPHOPANTETHEINE, CHLORIDE ION, ... 著者 Collin, S, Gruez, A. 登録日 2022-07-22 公開日 2023-03-15 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Decrypting the programming of beta-methylation in virginiamycin M biosynthesis. Nat Commun, 14, 2023
2Z8Y	Xenon-bound structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase(CODH/ACS) from Moorella thermoacetica 分子名称: COPPER (I) ION, Carbon monoxide dehydrogenase/acetyl CoA synthase subunit alpha, Carbon monoxide dehydrogenase/acetyl CoA synthase subunit beta, ... 著者 Doukov, T.I, Blasiak, L.C, Drennan, C.L. 登録日 2007-09-12 公開日 2008-03-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Xenon in and at the End of the Tunnel of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Biochemistry, 47, 2008
1ZAH	Fructose-1,6-bisphosphate aldolase from rabbit muscle 分子名称: Fructose-bisphosphate aldolase A 著者 St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. 登録日 2005-04-06 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit. J.Biol.Chem., 280, 2005
1ZF3	ATC Four-stranded DNA Holliday Junction 分子名称: 5'-D(*CP*CP*GP*AP*TP*AP*TP*CP*GP*G)-3', CALCIUM ION 著者 Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. 登録日 2005-04-19 公開日 2005-05-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZFH	TTA Duplex B-DNA 分子名称: 5'-D(*CP*CP*TP*AP*AP*TP*TP*AP*GP*G)-3' 著者 Hays, F.A, Teegarden, A.T, Jones, Z.J.R, Harms, M, Raup, D, Watson, J, Cavaliere, E, Ho, P.S. 登録日 2005-04-20 公開日 2005-05-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 How sequence defines structure: a crystallographic map of DNA structure and conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZG5	NarL complexed to narG-89 promoter palindromic tail-to-tail DNA site 分子名称: 5'-D(*CP*GP*TP*AP*CP*CP*CP*CP*TP*AP*TP*AP*GP*GP*GP*GP*TP*AP*CP*G)-3', Nitrate/nitrite response regulator protein narL, SULFATE ION 著者 Maris, A.E, Kaczor-Grzeskowiak, M, Ma, Z, Kopka, M.L, Gunsalus, R.P, Dickerson, R.E. 登録日 2005-04-20 公開日 2005-11-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Primary and Secondary Modes of DNA Recognition by the NarL Two-Component Response Regulator. Biochemistry, 44, 2005

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